Vaccine equity in Africa: a rapid review of policy, legal and governance frameworks to improve research and development
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John E. Ataguba, Grace Njeri Muriithi, Daniel Malik Achala
Background: Vaccines are instrumental in promoting preventive health and improving health outcomes globally. However, stark inequities in vaccine production, distribution, and access disproportionately burden low …
Green city development principles (GCDP) implementation level and its effects on lagos megacity residents’ well-being, Nigeria: A qualitative study
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Eghosa Noel Ekhaese, Kingsley Okechukwu Dimuna, Aniefon Essien
Cities are subject to rapid urbanisation, climate change and environmental challenges. Lagos, being the 4th most populous city in the world and Africa, is also …
Heavy metal and pesticide toxicity in agricultural soils across a farming intensity gradient in Central Zambia
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Aaron Chimbelya Siyunda, Davies Malekani Lungu, Natasha M. Mwila
Routine pesticide applications are an under‑recognized pathway for heavy metal accumulation in agricultural soils, particularly in sub‑Saharan Africa where synthetic pesticide use is expanding rapidly …
Indigenous knowledge systems and pandemic health resilience
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Wilfred Lunga, Charles Musarurwa, Mkhokheli Sithole
Introduction: Indigenous Knowledge Systems (IKS) have played important roles in community-based health responses across the Global South, yet they remain marginalized in formal health policy …
An integrated approach applied to anticancer drugs across aquatic compartments
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Aouatif Azaal, Bouchra Elguerrouj, Abdelali Ouasrhir
Anticancer drugs represent emerging contaminants in the water cycle, raising concerns due to their intrinsic biological activity, low concentrations, persistence, and potential toxicological effects.Despite growing …
Burnout, Workplace Factors, and Retention Indicators Among Nurses in a Rural District Hospital in the Eastern Cape, South Africa
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Ezile Ndamase, Nomfuneko Sithole, Eric Maimela
Background Burnout-related symptoms among nurses are a growing concern globally and may affect workforce well-being, patient care, and health system performance. In resource-constrained rural stableettings, …
Evaluation of thermocycling, color stability, surface roughness and hardness of nanocarbon HPP, BioHPP and PEEK used for fabrication of prosthetic restorations ( in vitro study)
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Mohamed Zaki Basiony, Rim Adel Selima, Nermeen Abdelsalam Rady
STATEMENT OF PROBLEM: The selection of appropriate dental materials plays a crucial role in the success of prosthetic restorations. With the limitations of metallic alloys, …
A single dose of azithromycin versus placebo for malaria in infants: A cluster-randomized trial
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Rikhard Ihamuotila, Jane Juma, Fadima Haidara
Azithromycin mass drug administration (MDA) has been shown to promote child survival in high mortality settings. Azithromycin has antimalarial effects, and one possible mechanism behind …
Lake Victoria to the Sudd Wetland: flood wave timing, connectivity and wetland buffering across the White Nile
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Douglas Mulangwa, Evet Naturinda, Charles Koboji
Abstract. The White Nile from Lake Victoria through Lakes Kyoga and Albert to the Sudd forms a complex lake-river-wetland corridor where flood propagation, storage, and …
An XGBoost-based predictive framework for diabetes mellitus multi-classification
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Moataz M. El Sherbiny, Mohamed G. Abdelfattah, Ali E. Takieldeen
Diabetes mellitus is a persistent metabolic condition that requires accurate and early diagnosis to prevent severe complications. This paper proposes an Extreme Gradient Boosting (XGBoost)-based …
Emerging risk factors affecting real estate development delivery in Accra, Ghana
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Kingsley Ofori, Simon Ofori Ametepey, Clinton Aigbavboa
Introduction This study examined emerging risk factors affecting real estate development delivery in Accra, Ghana, focusing on economic, institutional, market, and environmental risks. The study …
Neurogenesis and neuroplasticity activities of natural products: therapeutic potential in Alzheimer’s disease
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Abeer M. Shaheen, Mai H. A. Mousa, Merhan O. Hindam
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral disturbance, largely associated with amyloid-β accumulation, tau protein pathology, …
plsMD: a plasmid reconstruction tool from short-read assemblies
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Maryam Lotfi, Deena Jalal, Ahmed A. Sayed
Abstract Background While whole genome sequencing has become a cornerstone of antimicrobial resistance surveillance, the reconstruction of plasmid sequences from short-read data remains a challenge …
Impact of Digital Transformation on Student Development and Academic Performance among Students of the School of Business and Management Studies, Ogun State Institute of Technology, Igbesa
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Sabitu Olalekan Owotutu, Akinde Ibukunoluwa Elizabeth
Digital transformation has moved from an optional innovation to a structural feature of higher education, yet its effects on students in Nigerian polytechnics remain thinly …
The Smart Partnerships Approach in reducing poverty in Lesotho: A historical review
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Mankopane Violet Makhetha, Nomazulu Ngozwana
This study examines the contribution of the Smart Partnerships Approach to poverty reduction in Lesotho through a historical review of collective action practices and development …
Case Report: Diagnosis and Surgical Management of a Giant Ovarian Tumor: A Case Report
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Mejri Oumayma, Mehdi Binous, zeineb ben dhiaf
Introduction Giant ovarian cysts are now rare in contemporary practice due to widespread access to imaging and earlier diagnosis. However, they may still present as …
Extracellular Markers Staining Protocol for Flow Cytometry v1
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Moustafa Nouh Elemeery, Nathalie Labrecque
This protocol describes the standard procedure for staining cell surface antigens on single-cell suspensions from mouse spleen, lymph nodes, and/or thymus for flow cytometric analysis.
Intracellular Cytokine Staining (ICS) Protocol for FACS Analysis v1
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Moustafa Nouh Elemeery, Nathalie Labrecque
This protocol provides a comprehensive method for the intracellular staining of lymphocytic cells for Fluorescence-Activated Cell Sorting (FACS) analysis. The procedure outlines the steps for …
Adoptive Activated T cell Transfer Protocol v1
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Moustafa Nouh Elemeery, Nathalie Labrecque
This protocol covers isolation, in vitro activation, and intraperitoneal (i.p.) delivery of TCR-transgenic CD8+ T cells. Steps were performed and validated at cr-HMR (Universite de …
EXPLORED STUDY ON HUMAN GENDER IN THE QUR'AN: STATISTICAL APPROACH AND COMPARISON TO OTHER DIVINE BOOKS
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Mohammed; Mohammed V University of Rabat Houmine
The gender in Islam generally and in the Qur'an particularly has interested many authors, both muslims and non-muslims. Among them, certain Western authors have concluded …