Closing the gap between implementation science and policy in Nigeria: lessons from the Nigeria implementation science alliance using a nominal group technique
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Tonia C. Onyeka, Babayemi O. Olakunde, Otoyo Toyo
Introduction: Knowledge translation in healthcare has been of keen interest to researchers, practitioners, policymakers and administrators as it seeks to confront complex health issues within …
Assessment of compliance with good review practices by medicine assessors within the Zambia medicines regulatory authority
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Constance Sakala Chisha, S. Rebecca Leigh, Makomani Siyanga
Introduction: The implementation of Good Review Practices (GRevPs) ensures the timely, high-quality review and enhanced availability to safe, quality, and efficacious medicines. It is important, …
Recent advances in host models in studying virulence factors and pathogenesis of Acinetobacter baumannii
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Tadesse Lejisa Garomsa, Abebe Mekuria Shenkutie, Polly H. M. Leung
Acinetobacter baumannii is a major global healthcare-associated pathogen with increased antibiotic resistance, underscoring the urgent need to develop novel antibiotics, immunotherapies, and vaccines. However, a …
Implementing oral (event-driven and daily) and long-acting pre-exposure prophylaxis in mobile men in sub-Saharan Africa: a phase 3b, open-label, hybrid type 2 implementation and effectiveness trial (MOBILE MEN)
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Sylvia Kusemererwa, Bernadette Nayiga, Limakatso Lebina
BACKGROUND: Men who are mobile for work are a key population at high risk of acquiring HIV. Flexible pre-exposure prophylaxis (PrEP) options, including event-driven (ED) …
Evaluating the antimicrobial effect, compressive strength and fluoride release of glass ionomer cement modified with Triphala
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Yasmine Mohamed Afify, Gehan Allam, Ola Abd El-Geleel
The enhancement of the antibacterial properties of glass ionomer cement has gained substantial importance in contemporary restorative dentistry, as microbial biofilms are the primary cause …
Impact of malaria vector control interventions implemented in Luangwa District southeastern of Zambia: A 13-year observational time series analysis of malaria trends
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Dingani Chinula, Busiku Hamainza, Japhet Chiwaula
INTRODUCTION: Luangwa District has one of the longest running legacy datasets in Zambia regarding reliable monitoring of confirmed malaria cases through the national Health Management …
Gender disparities in post-war food insecurity among urban households in Tigray, Ethiopia
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Hafte Gebreselassie Gebrihet, Yibrah Hagos Gebresilassie
Abstract The conflict from 2020 to 2022 in Tigray, Ethiopia, has deepened food insecurity, particularly for female-headed urban households, which are 24.33% more likely to …
Epidemiological modeling of criminal gangs with multidelays persistence and intervention instability
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Oluwasegun Micheal Ibrahim, D. Okuonghae, M. N. O. Ikhile
Abstract Delay differential equation (DDE) model for the study of gang dynamics using insight from mathematical epidemiology. The criminal gang models possess multiple periodic time …
Developing a framework to guide intervention planning to reduce heat exposure and poor air quality in school classrooms: a scoping review protocol
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Natasha Naidoo, Thandi Kapwata, Muthise Bulani
INTRODUCTION: Poor indoor air quality and heat, individually and together, cause serious health impacts on children. Thus, there is a growing interest in creating school …
Exploring healthcare staff experiences with a hybrid paper/digital health management information system and their perspectives on digitalization as an alternative – A Tanzanian qualitative case study on perinatal data
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Mary E. Cronin, Lucy Munishi, Gaudensia Olomi
Quality health data is essential to improve delivery and outcomes of healthcare. This study explores the experiences of healthcare staff in Kilimanjaro, Tanzania, using a …
Joint predictors of antenatal care contacts and timing of antenatal care initiation among women of reproductive age in Ethiopia
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Abebew Aklog Asmare, Awoke Seyoum Tegegne, Denekew Bitew Belay
BACKGROUND: Maternal and neonatal mortality remain major public health challenges, particularly in low-income countries like Ethiopia. Antenatal care (ANC) plays a vital role in improving …
Geo-epidemiological risk stratification to select malaria interventions, case of Mali
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Mady Cissoko, Mahamadou Magassa, Ibrahim A. Cissé
Malaria is a public health threat in Mali, with high morbidity (37%) and mortality (25%) rates. Malaria risk stratification is needed to identify different risk …
Point prevalence and incidence of depressive and generalized anxiety symptoms among women attending antenatal clinics, a longitudinal study among adolescent mothers in Mwanza Tanzania
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Matiko Mwita, Scott Burton Patten, Deborah Dewey
BACKGROUND: Few studies have examined the point prevalence and incidence of perinatal mental disorders among the general population of pregnant women and no prior studies …
Microplastic mediated bacterial contamination in water distribution systems as an emerging public health threat
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Jibrin Ndejiko Mohammed, Feroz Mahomed Swalaha
Abstract The growing intrusion of microplastics (MPs) into water supply networks, exacerbated by their physicochemical features that facilitate their movement in water and enable microbial …
Support for tobacco endgame approaches: Results from a web-based survey of stakeholders from 28 African countries
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Catherine O. Egbe, Mukhethwa Londani, Siphesihle Gwambe
INTRODUCTION: The tobacco 'endgame' concept proposes moving beyond traditional tobacco control measures towards a tobacco-free future. The aim of this study is to investigate the …
Edge-Enabled Mobile App for Smart Agriculture Using Multi-Sensor Inputs and a Hybrid CNN–Vision Transformer Model
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Thomas Kinyanjui Njoroge, Rachael Njeri Kibuku, Kelvin Mugoye Sindu
Crop diseases significantly threaten food security, particularly in resource-limited regions. Existing mobile diagnostic tools often lack robustness and fail to integrate environmental context. To address …
Deep reinforcement learning framework for joint optimization of multi-RAT UAV location and user association in heterogeneous networks
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Mohamed G. Anany, Mahmoud M. Elmesalawy, Ahmed M. Abd El‐Haleem
The explosive growth of multimedia and Internet of Thing (IoT) devices has led to a huge increase in data traffic requirements with a reduced power …
In vitro and in silico analysis of the anti-proliferative effects of Spirulina platensis on A549 lung cancer cells
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Fatma I. Abo El‐Ela, Marwa A. Ibrahim, Salma I. El‐Samannoudy
Spirulina platensis (S. platensis) is a natural microalgae extract that exerts significant cytotoxic effects against different serious cancerous diseases. Lung cancer is one of the …
Bayesian and non-Bayesian estimation of the bivariate inverse Weibull distribution parameters using ranked set sampling with concomitant variable
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Hiba Zeyada Muhammed, Mostafa Shaaban
Estimating the bivariate distribution parameter is crucial for modeling paired variable dependencies, but highly variable or resource-intensive data may not respond well to traditional simple …
Nanoparticle delivery of combined plant extracts enhances immune response in immunocompromised rats
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Selvia S. Milad, Hisham A. Elshoky, Sara E. Ali
Recently, the world has been dealing with diseases that spread easily and weaken the body's natural defenses. Boosting natural immunity can help prevent these diseases. …