Prevalence of primary HIV-1 drug resistance among antiretroviral-naïve individuals in Togo in 2023: a national study
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Alassane Ouro‐médéli, Roméo Mèdéssè Togan, Laetitia Serrano
Monitoring pre-treatment drug resistance is a priority to assess the emergence of HIV resistance to antiretrovirals, especially in countries where the transition from dolutegravir-based regimens …
Time to phlebitis onsite and its predictors among admitted patients with peripheral intravenous cannulas at Debre Markos Comprehensive Specialized Hospital, Northwest Ethiopia, 2024/ 2025: A prospective follow-up study
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Zinaw Beyene, Haymanot Zeleke, Tesfahun Ayenew
INTRODUCTION: Phlebitis due to peripheral intravenous cannulation is a common issue in hospitalized patients which leading to serious complications such as deep vein and pulmonary …
Prevalence and determinants of anemia among HIV-positive children in central Uganda: A cross sectional study
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Abdirashid Dahir Herow, Grace Ndeezi, Joel Kimera
BACKGROUND: Anemia remains a critical public health issue, especially in low-resource settings like Uganda, with severe consequences especially in HIV-positive children. Limited research has been …
Socioeconomic and demographic determinants of tobacco use in Kenya: A secondary data analysis of findings from the Kenya Demographic and Health Survey 2022
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Peter Magati, Jeffrey M. Drope, Raphael Lencucha
INTRODUCTION: Tobacco use is a major public health crisis in Kenya, leading to over 6000 deaths annually. With a significant number of young people and …
Comparative safety of cholinesterase inhibitors and memantine for dementia: a protocol for a network meta-analysis of randomized controlled trials
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Moaz Elsayed Abouelmagd, Nereen A. Almosilhy, Hamdy A. Makhlouf
Abstract Background Dementia is a growing public health concern, affecting over 55 million people worldwide, with Alzheimer’s disease (AD) being the most prevalent cause. Cholinesterase …
The low genetic diversity of the Jingmen tick virus in Guinea sheds light on the recent introduction of the virus to West Africa
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Marat T. Makenov, Sanaba Boumbaly, Tatiana A Bondarenko
BACKGROUND: Jingmen tick virus (JMTV), a segmented orthoflavi-like virus, has been recognized in recent years as a potential human and animal pathogen, with confirmed detections …
Determinants of loss to follow-up in HIV care among adults on ART at Adama Hospital Medical College, Ethiopia: a case-control study
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Temesgen Oljira, Abebe Megerso, Alem Deksisa
BACKGROUND: In recent decades, the availability of antiretroviral therapy services has grown significantly, resulting in a reduction in both morbidity and mortality rates among patients …
Factors associated with mental health stigma among teachers and caregivers of primary school children in Uganda
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Nora Braathu, Mukisa Marjorie Kabatooro, Juliet N. Babirye
BACKGROUND: Uganda has one of the youngest populations in the world, with around 55% aged below 18 years. Approximately 23% of Ugandan youths are struggling …
Genetic polymorphism of Plasmodium falciparum circumsporozoite protein in Kigali, Rwanda
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Sandra Noukimi Fankem, Jean-Bosco Mbonimpa, Edgar Kalimba
Introduction: Malaria remains a major public health challenge across sub-Saharan Africa, with Plasmodium falciparum responsible for the vast majority of cases and deaths. In Rwanda, …
Beijing +30: a global and Zambian review of women’s political participation and their impact on development outcomes
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Patricia Ndhlovu
This study examines global and Zambian progress on women’s parliamentary participation from 1995 to 2025, in line with Section G of the Beijing Declaration and …
Targeting asparagine and cysteine in SARS-CoV-2 variants and human pro-inflammatory mediators to alleviate COVID-19 severity; a cross-section and in-silico study
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Hewida H. Fadel, Hadeer Adel EL-Esseily, Mohamed Abdel-Rahman
To date, COVID-19 continues to pose a global health challenge, with substantial morbidity, mortality, and long-term post-COVID-19 complications threatening public health resilience. During the early …
Gendered mediating role of substance use in the path from internet addiction or gambling to active violence in youth in the region of Mahdia, Tunisia
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Imen Mlouki, Safa Hssan, Emna Hariz
Introduction: The literature shows a gap regarding mechanisms and mediators explaining the path from IA and gambling to violence. Our study aimed to investigate the …
Knowledge, attitude, and practices regarding TB among senior management officials of companies with increased silica dust exposure in Lusaka and Southern provinces of Zambia
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Luciano Mutti, Mary Kagujje, Daniel Siameka
Introduction A high burden of tuberculosis (TB) complicated by occupational risk factors implies a need for the workplace to develop strategies to reduce workplace incidence …
Characterization of Androctonus mauritanicus venom and in vitro screening of SARS-CoV-2 entry inhibitors candidates
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Reda Chahir, Jacob Anthony Galan, Hicham Hboub
Animal venom, known for its complex biochemical composition, presents a valuable source of therapeutic molecules, particularly for antiviral applications. Despite this potential, the industrial use …
Surgical management and outcome of medulloblastoma patients at Addis Ababa between 2010 and 2018
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Yemisirach Bizuneh Akililu, Éric Bouffet, Mersha Abebe
Background: Medulloblastoma is the most common malignant central nervous system tumor in pediatric patients and is relatively rare in adults. Despite remarkable improvement in survival …
The influence of incorporation of hydroxyapatite/collagen nanocomposite into glass ionomer cement on surface roughness, microhardness, and fluoride-ion release potential
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Mostafa Ahmed Abdelshafi, Ahmed Elsebaai, Kareem Hamdi
OBJECTIVE: To investigate the effect of incorporation of 5 and 10 weight% of hydroxyapatite /collagen (HA/Col) nanocomposite with different ratios (50:50) and (70:30) to conventional …
A qualitative study of peer education experiences and oral pre-exposure prophylaxis use among adolescent girls and young women at high risk of HIV acquisition in Kampala, Uganda
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Yunia Mayanja, Ivy Kayesu, Zam Nabalwanyi
Introduction: Oral pre-exposure prophylaxis (PrEP) use remains low among adolescent girls and young women (AGYW) at high HIV risk in Eastern and Southern Africa. Most …
Ultrasound assisted extraction enhances phytochemical profile and functional properties of moringa leaf extract with protection against gentamicin induced nephrotoxicity
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Asmaa M. Shehata, Sanaa M. Abdel-Hameed, Aliaa Anter
Abstract Moringa oleifera is a rich source of therapeutic bioactive compounds, which may protect renal function against gentamicin (GN) induced toxicity. This study applied green …
Modulation of experimental Alzheimer’s disease in rats through donepezil-loaded CSF implant
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Lamyaa Osama, Shaimaa ElShebiney, Hanan H. Beherei
Alzheimer's disease (AD) is a growing challenge worldwide, with current treatments largely symptomatic and limited. The current study aimed to introduce coated nanoporous membranes for …
WatchListR: a tool for developing watch-lists of invasive species to inform biosecurity decision-making
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Philip Ivey, Katelyn T. Faulkner, Justin Miller
The Global Biodiversity Framework calls for member countries to reduce the rate of introduction of known or potential invasive alien species by at least 50 …