Synthesis, antimicrobial evaluation, and computational investigation of new triazine-based compounds via DFT and molecular docking
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Aisha O. Hussain, Aisha Y. Hassan, Anhar Abdel‐Aziem
A green synthesis protocol produced triazine derivatives such as imidazo-triazine, pyrimido-triazine, pyrazolotriazine, and triazolotriazine, which were subsequently evaluated for their antimicrobial activity.
Purification of vegetable oils from acrylamide pollutants using metal-organic frameworks
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Reda M. Abdelhameed, Randa S. Hasan, Hassan Abdel‐Gawad
Acrylamide is a chemical compound that can form in certain foods during high-temperature cooking processes like frying, roasting, and baking. The presence of acrylamide in …
Plasma lipopolysaccharide levels predict mortality in acutely ill children in Low- and Middle-Income Countries
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Christopher Allen, Arya Ghate, James M. Njunge
Childhood mortality remains high in low-resource settings, where environmental enteric dysfunction (EED) is prevalent. Peripheral blood bacterial lipopolysaccharides (LPS) are potential biomarkers of intestinal microbial …
Inflammation impairs post-hospital discharge growth among children hospitalised with acute illness in sub-Saharan Africa and south Asia
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James M. Njunge, Evans O. Mudibo, Jasper Bogaert
In resource-limited settings, children often experience poor growth following illness, but the mechanisms are poorly understood. This cohort study in six countries in sub-Saharan Africa …
Assessment of cytotoxicity of some synthetic compounds against breast carcinoma spheroids with subsequent analysis of pro-apoptotic and gene expression
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Khaled Mahmoud, Elham Mohamed Youssef, Farid M. Sroor
Abstract The current study examined the anticancer potential of 80 synthetic organic compounds at 50µM using in vitro two-dimensional (2D) and three-dimensional (3D) spheroids model …
Effect of drying methods and pretreatments on the physical and antioxidant properties of prickly pear (Opuntia stricta and Opuntia ficus-indica)
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Ruth Nyamgero, Peter Kahenya Kinyanjui, Willis Owino
The invasive proliferation of prickly pear ( Opuntia stricta [OS] and Opuntia ficus - indica [OFI]) in arid regions offers an opportunity to source a …
Prevalence of sexual coercion and associated factors among adolescents and young adults in Africa: a systematic review and meta-analysis
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Posi Emmanuel Aduroja, Adebukunola Olajumoke Afolabi, Ayobami A. Bakare
Introduction: Sexual coercion is a major public health and human rights concern, yet its burden among African adolescents and young adults remains poorly synthesized. This …
A patient-centred comparison of the public and private healthcare service quality: insights from the SERVQUAL model
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Awinaba Amoah Adongo, Robert Kuchengye Mokulogo, Dominic Nabil Bodpii
Abstract Background The quality of healthcare services is a critical factor influencing patient satisfaction, trust, and overall health outcomes. In many countries, both public and …
Assessment of climate change impacts on crop and irrigation water demand in the Awash River basin of Ethiopia using CMIP6 models
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Elias Meskelu, Mekonen Ayana, Dereje Birhanu
Abstract Irrigation water is crucial for global food security, but it is increasingly vulnerable to climate change. Accurate projections of irrigation water demand under climate …
Within reach? Sustainable energy infrastructure financing for “hardest to reach” communities
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Whitney Pailman, Federico Caprotti, Penlope Yaguma
Providing energy access in “hard to reach” under- or unelectrified contexts like informal settlements or remote rural regions requires rethinking how we develop and finance …
High awareness, low compliance: rabies knowledge and dog ownership practices among pastoralists, Marsabit County, Kenya
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Pauline Gitonga, Brian Ogoti, Teresa Lopuwa Etapar
Introduction Rabies is a fatal yet preventable zoonotic disease that disproportionately affects underserved communities in endemic regions. Understanding community-level Knowledge, Attitudes, and Practices (KAP) is …
“It isn't because they don't love their children”: social norms shaping young fathers' caregiving in Uganda
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Aloysious Nnyombi, Ramadhan Kirunda, Anslem Wandega
This study investigates the influence of social norms on male caregiving in Uganda and considers the implications for tailoring and scaling the REAL Fathers mentoring …
Dual proton transport in Schiff base-modified chitosan functionalized with AMPS for fuel cell applications
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Sonia Jebri, Walid A. Mabrouk, Ridha Elleuch
Abstract Proton exchange membranes (PEMs) require high proton conductivity, stability, and durability for fuel cell applications. This study reports the synthesis of N-(2-acrylamido-2-methylpropane sulfonyl) chitosan …
Exploring perceived social support, self-compassion, and life satisfaction as pathways to psychological well-being of older adults in rural Nigeria
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Wisdom Chidiebere Obioha, Nkechi Angela Chukwuemeka, Ikenna Donatus Okechi
Abstract Background Perceived social support has been identified as both protective and promotive factor for the psychological well-being of older adults in various contexts and …
Mitigating cathode biofouling in membrane-less MFCs using CuO-doped activated carbon: a comparative study of batch and continuous modes
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Nasser A.M. Barakat, Hazem Gamal, Rania Osama
Abstract A membrane-less microbial fuel cell system was developed and evaluated using CuO-incorporated activated carbon (CuO/AC) cathodes designed for dual functionality: enhanced oxygen reduction reaction …
Gendered risk perceptions and structural barriers to sustainable pest management: evidence from Uganda’s tomato value chain
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Alex Mayamba, Benson Mutuku, Oscar Ingasia Ayuya
Sustainable pest management amid the intensifying adverse effects of climate change is critical to the resilience of agrifood systems. Yet the transition to low-risk and …
Sustainable gelatine–alginate biopolymer binder enhancing pigment printing and functional performance of textiles
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Nermin Atef Ibrahim, Heba M. El-Hennawi, Safia A. Mahmoud
This study investigates gelatine and sodium alginate as novel thickening agents for pigment textile printing using natural eco-friendly binders. As a thickener and binder, gelatine …
Exploring the role of chitosan and curcumin-loaded chitosan nanoparticles against chronic toxoplasma infection in experimental mice
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Abeer A. Khedr, Nashwa Hamad, Salwa Mahmoud Abd-Elrahman
Toxoplasma gondii infection remains a significant global health concern, promoting the urgent need for effective therapeutic strategies. This study aimed to evaluate the therapeutic potential …
Supporting One Health policies to manage antibiotic resistance in Senegal: a systems analysis using group model building
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Mouhamadou Moustapha Sow, Mamadou Ciss, Nicolas D. Diouf
Introduction: Antibiotic resistance (ABR) is a growing public health issue in Senegal, driven by interconnected factors across human, animal, and ecosystem health. This study applied …
Uptake and factors associated with cervical cancer screening among women aged 18–49 years at a public hospital in Coastal Kenya
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Dennis Mose, Geoffrey G. Katana, Stevenson K. Chea
Cervical cancer remains a public health concern in sub-Saharan Africa. In Kenya, data on cervical cancer screening is limited therefore hindering planning of targeted interventions. …