Diversity of Salmonella enterica isolates from urban river and sewage water in Blantyre, Malawi
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Jonathan Rigby, Catherine N. Wilson, Allan Zuza
BACKGROUND: Salmonella enterica encompasses over 2,600 serovars, including several commonly associated with severe infection in humans. Salmonella is a major cause of sepsis in Africa; …
People-centered strategies to mobilize people living with disabilities due to Neglected Tropical Diseases (PD-NTDs) to influence policy and programs: A mixed-methods study in Côte d’Ivoire
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Julien Aké, Eunheh Koh, Tiembré Issiaka
INTRODUCTION: Neglected tropical diseases (NTDs) are a priority in the public health agenda for Côte d'Ivoire, with persons living with disabilities due to NTDs (PD-NTDs) …
Mathematical modeling of the effect of early detection in breast cancer treatment
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Farouk Tijjani Saad, Yusuf Y. Gambo, Phollakrit Wongsantisuk
Introduction: Early detection is a cornerstone of cancer control, yet its quantitative influence on tumor-immune interactions remains underexplored in mathematical oncology. Methods: We formulated a …
Reducing emergency department length of stay for hematology patients of tikur anbessa specialized hospital: An improvement initiative
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Merahi Kefyalew Merahi, Rahel Argaw, Aschalew Worku
INTRODUCTION: Prolonged Emergency Department (ED) stays, a global issue driving overcrowding, were exacerbated at our hospital by lab delays and extended waits, increasing patient stress. …
Territorial and gender-linked risk factors for Buruli ulcer in Southern Benin: A case-control study using geographic and behavioral surveying
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Harvey Johnson, Alexandra Boccarossa, Sèdjro Gimatal Esaï Anagonou
OBJECTIVES: The manuscript examines the risk factors associated with Buruli ulcer in endemic regions of Benin, focusing on community practices, agricultural activities, and age and …
Community-directed treatment with ivermectin in Maridi, South Sudan: Impact of an onchocerciasis awareness campaign and bi-annual treatment on therapeutic coverage
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Joseph Nelson Siewe Fodjo, Moses Okwii, Stephen Raimon Jada
BACKGROUND: A high onchocerciasis disease burden and a low coverage of community-directed treatment with ivermectin (CDTI) have been observed in many parts of South Sudan. …
Enhanced hydrological modeling with the WRF-Hydro lake–reservoir module at a convection-permitting scale: a case study of the Tana River basin in East Africa
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Ling Zhang, Lu Li, Zhongshi Zhang
East Africa frequently experiences extreme hydrological events, such as droughts and floods, underscoring the urgent need for improved hydrological simulations to enhance prediction accuracy and …
COVID-19 vaccine hesitancy in Ethiopia: a scoping review for equitable vaccine access
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Senait Alemayehu Beshah, Jibril Bashir Adem, Mosisa Bekele Degefa
Introduction: COVID-19 vaccines are crucial for preventing severe illness from the virus. Despite their effectiveness; vaccine hesitancy, unequal access, and economic disparities hinder vaccination programs …
Burden of tuberculosis in Eastern Africa region from 1990–2021: A systematic analysis for the Global Burden of Disease 2021 Study
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Leltework Yismaw, Temesgen Zewotir, Essey Kebede Muluneh
BACKGROUND: Tuberculosis (TB), despite being a preventable and curable disease, remains a leading infectious cause of death. In Eastern Africa, TB poses a significant public …
Coagulation markers as independent predictors of colorectal cancer aggressiveness
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Hanaa Ali EL-Sayed, Doaa H. Sakr, Mohamed K. Abdelhakiem
BACKGROUND: Colorectal cancer (CRC) is frequently associated with thrombosis with thrombotic events, such as deep vein thrombosis or pulmonary embolism, often correlate with poor clinical …
Improving the specimen referral system in Ghana: findings from a landscape assessment
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Christopher Nkrumah, Paa Kobina Forson, Bernard Nkrumah
Introduction: Ghana's specimen referral system (SRS) is driven by vertical surveillance programs and outbreak response events; the lack of integration limits public health disease surveillance …
Repeated introductions and widespread transmission of human metapneumovirus in Côte d’Ivoire
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Hervé Kadjo, Sairah M. Khan, Sana Tamim
In Cote d'Ivoire, the incidence rate of acute respiratory infections (ARIs) rose from 165 cases per 1000 children in 2014 to more than 200 cases …
Combining mental health and climate-smart agricultural interventions to improve food security in humanitarian settings: study protocol for the THRIVE cluster-randomized controlled trial with mothers in Nakivale refugee settlement, Uganda
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Jonathan Hall, Herbert Ainamani, Phaidon Vassiliou
BACKGROUND: Climate extremes in Africa threaten the food security of war-affected refugees, who often experience mental health challenges that hinder their capacity for agricultural adaptation. …
Valorization of novel bifunctional waterborne coatings with UV irradiation resistance and antimicrobial activity
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Walaa M. Abd El‐Gawad, Hossam M. El‐Masry, T. A. Zidan
This research aimed to create bifunctional acrylic waterborne coatings capable of absorbing UV radiation and resisting microbial growth. The compound 4-[2(3-acetylphenyl) diazenyl]-3,5-dimethylphenol (ADD) was incorporated …
Community literacy club and family language policymaking initiatives for biliteracy development
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Xolisa Guzula, Babalwayashe Molate
Background: Our article analyses two case studies that show an urban South African family and members of a community literacy club engaging in grassroots initiatives …
Mapping human fatalities from megafauna to inform coexistence strategies
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Blessing Kavhu, Courage Mutema, Kudzai Shaun Mpakairi
Human fatalities from human-wildlife conflict (HWC) represent a critical dimension of conservation, often triggering retaliatory actions and post-traumatic stress in affected communities. However, most studies …
A Later Stone Age quartz knapping workshop and fireplace dated to the Early Holocene in Senegal: The Ravin Blanc X site (RBX)
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Charlotte Pruvost, Éric Huysecom, Aline Garnier
Well-dated and well-preserved Later Stone Age sites are unfortunately scarce in West Africa. The few known ones exhibit significant typo-technical variability, reflecting diverse socio-cultural behaviors …
Architectural Memory: Créole Houses as Living Monuments in Port Louis, Mauritius
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Kawthar Rashid Jeewa, Magda Minguzzi
This study examines the vernacular architecture of Port Louis in Mauritius island through Créole houses. These houses development because the early architecture of the French …
Plant-based management of Iron Deficiency Anemia (IDA) in East Africa community: a systematic review
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Robert Siida, Ilemobayo Victor Fasogbon, Angela Mumbua Musyoka
Background Iron Deficiency Anaemia (IDA) is a major public health challenge in East Africa, particularly affecting children and women. Conventional therapies are often limited by …
Characterization of Klebsiella pneumoniae Virulence and Biofilm Formation Patterns in Southwestern Nigeria
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Gbolabo Odewale, Olufunmilola Bamidele Makanjuola, Richard Olulowo Ojedele
Background: Klebsiella pneumoniae possesses a range of virulence factors that enable this bacterium to colonize, persist, adhere to host tissues, invade, and cause disease. The …