Internal quality assessment of blood components at Mansoura university blood transfusion center
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Doaa Shahin, Amira M. Tawfeek, Omnia Khaled
In modern blood banking, quality control of blood products ensures the timely availability of a blood component of high-quality yield with maximum efficacy and minimal …
Metabolic identification of bioactive compounds of Citrus reticulata cultivars extracts for a novel approach to polycystic ovary syndrome
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Shaimaa A. El Zanaty, Salwa A. Abu El Wafa, Mohammed A. Hussein
Polycystic ovary syndrome; is a prevalent endocrine disorder, characterized by hormonal imbalances, inflammation, and oxidative stress. Natural remedies, including Murcott and Merav (Citrus reticulata varieties, …
Impact of genotyping (PTPN2, rs2542151) and (MBOAT7, rs641738) in prediction of fibrosis in Metabolic dysfunction- associated steatotic liver disease’ patients
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Shimaa Abdelsattar, Hiba S. Al-Amodi, Hala F. M. Kamel
Introduction Numerous risk loci have been identified to have an essential role in Metabolic associated steatotic liver disease (MASLD) susceptibility and progression. The role of …
Adaptive foraging strategies of indigenous and exotic cattle breeds in semi-arid communal rangelands: implications for bush encroachment and climate resilience
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Mhlangabezi Slayi, Monde Rapiya
This study investigated diurnal and seasonal variations in forage selection, grazing behaviour, nutrient intake, and physiological responses of Nguni (indigenous) and Bonsmara (exotic) cattle in …
Concordance of coverage estimates from routine and survey data of measles second dose vaccine in Western Kenya
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Angela K. Moturi, Moses M. Musau, Samuel K. Muchiri
Background Missed opportunities for key vaccinations continue to exacerbate disease outbreaks. Accurately monitoring immunisation coverage is fundamental to identifying gaps in vaccine delivery and informing …
Seroprevalence of antibodies to Plasmodium falciparum transmission-blocking target proteins Pfs230D1M and Pfs48/45 in Tanzanian populations of diverse malaria transmission intensity
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Charles Mulamba, Wilmina F. Kalinga, Ivanny M. Mtaka
Transmission-blocking vaccines are among the novel tools under development for malaria control and elimination. Understanding the human immune response to the sexual stages of Plasmodium …
Trends in maternal mortality and stillbirths by county in health facility data, Kenya, 2011-2022
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Rose Muthee, Martin Kavao Mutua, Helen Kiarie
BACKGROUND: Reports on maternal deaths and stillbirths in health facilities are a critical but underutilized source of information to monitor the quality of care. In …
Induction of an early IFN-γ cellular response and high plasma levels of SDF-1α are inversely associated with COVID-19 severity and residence in rural areas in Kenyan patients
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Perpetual Wanjiku, Benedict Orindi, John Kimotho
INTRODUCTION: COVID-19 was less severe in Sub-Saharan Africa (SSA) compared with Europe and North America. It is unclear whether these differences could be explained immunologically. …
Minimum dietary diversity and its associated factors among children aged 6–23 months in Senegal: Evidence from the demographic and health survey, 2023
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Enyew Getaneh Mekonen
BACKGROUND: Children between the ages of 6 and 23 months should be provided a variety of foods to ensure that their nutrient needs are satisfied, …
Barriers and enablers of community-based health insurance enrollment in the Sidama national regional state, Southern Ethiopia, 2024: A qualitative study
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Kare Chawicha Debessa, Keneni Gutema Negeri, Mesay Hailu Dangisso
The universal health coverage (UHC) efforts in low- and middle-income countries such as Ethiopia encounter significant challenges in the implementation of community-based health insurance (CBHI) …
Quantitative Evidence of Perceived Organizational Support and Employee Job Satisfaction of Teachers in Government-Aided Primary Schools in Bushenyi District, Uganda
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Donozio Kiiza, Lucy Aja, Tukur Muhammad
This study explores the relationship between perceived organizational support and employee job satisfaction, focusing on how rewards, recognition, and training influence teachers’ experiences in their …
Determinants of sexually transmitted infection-related care-seeking behavior among reproductive-age women in sub-Saharan Africa: A multilevel analysis
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Agazhe Aemro, Mohammed Seid Ali, Alebachew Ferede Zegeye
BACKGROUND: Sexually transmitted infections (STIs) remain a major public health threats in sub-Saharan Africa (SSA). Delay in seeking care is a significant barrier for the …
Insights into impact of polar protic and aprotic solvents on bioactive features of 3-(Dimethylaminomethyl)-5-nitroindole: A DFT study and molecular dynamics simulations
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Stève–Jonathan Koyambo-Konzapa, Berthelot Saïd Duvalier Ramlina Vamhindi, Bekzod Khudaykulov
Polar protic and aprotic solvents can effectively simulate the maturation of breast carcinoma cells. Herein, the influence of polar protic solvents (water and ethanol) and …
Coping and social cohesion mechanisms in addressing climate change and land degradation in Ghana
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Harry Quaye Amankwah, Hycenth Tim Ndah, Johannes Schuler
The West Africa sub-region is faced with major interlinked challenges in ensuring sustainable livelihoods in the context of climate change and land degradation. To ensure …
A diffusion-based HIV model with inflammatory cytokines and adaptive immune impairment
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Noura H. AlShamrani
HIV continues to pose a critical threat to global public health, contributing to a high number of deaths worldwide. The virus predominantly attacks CD4+T lymphocytes, …
Plasmodium telomere maintenance: uncovering the Achilles’ heel for novel antimalarials
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Theophilus Nang Wakai, Dorathy Olo Anzaku, Israel Sunmola Afolabi
This review examines the potential of disrupting telomere maintenance in Plasmodium as a novel antimalarial strategy. Telomeres are repetitive DNA–protein structures located at chromosome termini, …
Quantitative MRI Dixon signal drop and fat fraction for differentiating bone marrow lesions: a two-center prospective analysis
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Maha Ibrahim Metwally, Yassir Edrees Almalki, Marwa Fathy Khalil
BACKGROUND: Bone marrow (BM) lesion differentiation remains challenging, and quantitative magnetic resonance imaging (MRI) may enhance accuracy over conventional methods. We evaluated the diagnostic value …
Harnessing community-based one health interventions implementation beyond Mpox outbreak management in Africa: insights and benefits
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Ernest Tambo, Brice G Djopmo, Joelle N Djamfa
BACKGROUND: Little is documented on key community-based One Health (OH) approach implementation, pro-activeness and effectiveness of interactions and strategies against Mpox outbreak public health emergency …
Preduodenal portal vein: a case series of variable clinical presentations and surgical implications
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Ahmed Arafa, Abdelhafeez Mohamed Abdelhafez, Ahmed Shaker Ragab
AIM OF THE STUDY: To present a case series of four pediatric patients with PDPV, each with a different clinical presentation and surgical management. METHODS: …
Production, optimization and characterization of esterase isolated from a new endophytic Trichoderma afroharzianum strain AUMC 16,433 and its applications in dye decolorization
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Yehia A.‐G. Mahmoud, Nisrin S Alamin, Tarek M. Mohamed
BACKGROUND AND AIM: Synthetic dyes in the textile industry pose risks to human health and environmental safety. The current study aims to examine the efficacy …