Challenges and opportunities in the okra (Abelmoschus spp.) seed system in Benin
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Jelila S. Blalogoe, Mathieu Anatole Tele Ayenan, Lys Amavi Aglinglo
Introduction Well-functioning seed systems are essential for disseminating improved crop varieties and boosting agricultural production. Understanding their functioning is key to designing tailored interventions. This …
Cranberry improves metabolic syndrome-related organ dysfunction in rats by modulating AMPK/SREBP1, ROCK1 and TGF-β1
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Sahar M. Elashmony, Yosra Zakariyya Alhindi, Dina H. Merzeban
Metabolic syndrome (MetS) is a widespread, complex health issue that poses a substantial global health burden with increased healthcare costs and reduced quality of life, …
The potential protective effects of fermented extra virgin olive oil on high-fructose diet-induced non-alcoholic steatohepatitis in rats
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Hend A. Essa, Abeer E. El‐Metwally, Nadia A. Elkady
Abstract Non-alcoholic steatohepatitis (NASH), a progressive form of NAFLD, is strongly associated with high-fructose diets. We investigated whether microbial fermentation could enhance the known hepatoprotective …
Characterization and optimization of biogenic copper nanoparticles synthesized by Pseudomonas putida with cytocompatibility investigation
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Osama M. El-Sayed, Basma T. Abd-Elhalim, Mohamed A. Mohamed
One area of science that is experiencing rapid growth is nanotechnology. The goal of nanotechnology research is to develop novel, economical, safe, and effective methods …
Marine-derived peptides from Rapana venosa inhibit breast cancer cell growth through synergistic mechanisms with doxorubicin
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Mai A. Saleh, Hassan M.M. Masoud, Mohamed R. Habib
Abstract Marine natural products are a promising source of novel anticancer agents. This study evaluated the antitumor activity of peptide fractions derived from the marine …
Multivariate stability statistics of genotype by environment interaction on fresh yield of cowpea
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Mona M. F. Ghazy, W. M. B. Yehia, Essam Fathy El‐Hashash
The current study aims to assess the ten cowpea genotypes that are stable and adaptive under three locations during the growth seasons of 2021, 2022, …
Diagnostic and prognostic utility of salivary and serum procalcitonin, interleukin-6, and interleukin-10 in pediatric pneumonia: a prospective case-control study
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Ahmed R. Rezk, Nehad Ahmed Bakry, Samar M. Elfiky
Objectives: Effective biomarkers are essential for improving the diagnosis and risk stratification of pediatric pneumonia. This study aimed to evaluate the diagnostic and prognostic utility …
Advancing economic growth through human capital development in the era of the Fourth Industrial Revolution
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Calvin Mabaso, Angie Ontong
Orientation: Economic growth is a national priority for South Africa, yet poverty, inequality, and unemployment persist. This study examines human capital development (HCD) as a …
Climatic and endothermic thermal stress adaptation may be a major driver of emerging and emergent multidrug resistant fungi
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Chibuike Ibe, Carolina H. Pohl
Background: The impact of climate change and increasing global temperature is contributing to the emergence of unknown and the reemergence of known fungal pathogens. Main …
Coupling human development and adaptation through enhancing adaptive capacity and equity in climate change adaptation projects: Insights from practitioners in Ghana, Kenya, and South Africa
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Sheona Shackleton, Nadine Methner, Darlington Sibanda
The impacts of and the ability to respond to climate change are closely intertwined with poverty, inequality and inequity. Addressing the underlying development and structural …
Postharvest handling of indigenous vegetables in Ghana: implications for reducing food loss and enhancing nutrition
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Gloria Ladjeh Essilfie, Rosalyne Naa Norkor Baddoo, S. Ayibor
Postharvest deterioration of horticultural crops, including indigenous, traditional, neglected and underutilized vegetables continues to present significant challenges across Ghana’s agricultural value chains. These crops are …
Lessons from Ethiopian pharmaceutical regulation: a risk-based approach to overcome challenges and unlock opportunities
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Hassen Kebede Hassen, Yesuneh Tefera Mekasha, Addisu Afrassa Tegegne
Background: Pharmaceutical products are essential for disease prevention, treatment, and public health promotion. With the rapid growth of the global pharmaceutical industry in terms of …
A System Stretched Beyond Its Elastic Limits: The South African Foster Care Grant System
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Sipho Sibanda
Foster care placements are temporary care arrangements for children removed from their biological families due to a plethora of reasons. The social worker investigates the …
Identifying care gaps along the HIV treatment failure cascade: A multistate analysis of viral load monitoring, re-suppression, and regimen switches in Zambia
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Kombatende Sikombe, Noelle Le Tourneau, Brian Rice
BACKGROUND: Timely response to treatment failure is critical for improved outcomes and viral re-suppression among people living with HIV, but care gaps along the treatment …
Antiarthritic activities of berberine in a rat model of gouty arthritis
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Ghadha Ibrahim Fouad, Hanan F. Aly, Mohamed B. Shalaby
Gouty arthritis (GA) is an inflammatory arthritic disorder that is characterized by intense, acute inflammatory responses, such as synovitis and arthritis that occur due to …
Impact of tailored diabetes education on adherence and glycemic control in children and adolescents on continuous subcutaneous insulin infusion, prospective interventional study in a tertiary center
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Mona M. Hassan, Mahmoud ElHelaly, Nora Badawi
BACKGROUND: Structured diabetes education plays a crucial role in the management of Type 1 Diabetes (T1D), especially with advanced technologies such as continuous subcutaneous insulin …
Optimized biosynthesis of bioactive silver nanoparticle-kombucha cellulose nanocomposites for enhanced antimicrobial applications
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M. Bassam Aboul-Nasr, Alaa A. Yasien, Sabah S. Mohamed
Abstract Sustainable biosynthesis of monodisperse, bioactive silver nanoparticles (AgNPs) integrated with nanofabricated kombucha SCOBY cellulose membrane (KC) was achieved using the endophytic fungus A . …
The duplicated cytochrome P450 CYP6P9a/b confers cross-resistance to a mitochondrial complex I inhibitor in the African malaria vector Anopheles funestus
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Theofelix A. Tekoh, Leon M. J. Mugenzi, Benjamin D. Menze
Metabolic resistance to pyrethroids driven by cytochrome P450s is threatening malaria control interventions and may provide cross-resistance to insecticides with unrelated modes of action. Here, …
A low-cost IoT-based smart home automation system for urban sustainability in Mogadishu, Somalia
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Mohamed Abdirahman Addow, Abdukadir Dahir Jimale, Abdulaziz Yasin Nageye
Abstract As Mogadishu undergoes rapid urbanization, the demand for efficient, secure, and sustainable living environments has grown significantly. This paper presents the development and implementation …
Acceptability and feasibility of a multicomponent intervention to improve acute myocardial infarction care in Northern Tanzania: The MIMIC pilot trial
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Julian T. Hertz, Francis Sakita, Kelvin F. Haukila
BACKGROUND: The Multicomponent Intervention to Improve Acute Myocardial Infarction Care (MIMIC) was developed to increase the uptake of evidence-based care for acute myocardial infarction in …