Keratin/alginate microspheres as a novel pH-dependent polymer for colon-targeted delivery of dexamethasone for the management of inflammatory bowel disease
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Ogochukwu A. Meko, Sylvester Okhuelegbe Eraga, Matthew Ikhuoria Arhewoh
Purpose: To develop keratin/alginate microspheres loaded with dexamethasone for managing inflammatory bowel disease (IBD), enabling targeted delivery to the colon and minimizing systemic side effects …
Histopathological evaluation of D’General Bitters on renal health in adult male Wistar rats
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Darlington Nnamdi Onyejike, Darlington Cyprain Akukwu, Fortune Oghenekaro Abrukwe
Purpose: To evaluate the potential nephrotoxic effects of D’General Bitters through histopathological analysis.Methods: A total of 32 male Wistar rats weighing between 195 and 230 …
Analysis of chitosan nanoparticles synthesized from cowry and oyster shell byproducts using Cymbopogon citratus and silver nitrate
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Ejiro Prosper Awhin, Iruoghene Onosakponome, Alfred I. Ajoh
Purpose: To determine the properties of chitosan nanoparticles synthesized from Cymbopogon citratus and silver nitrate (AgNO3).Methods: Chitosan nanoparticles (CNPs) were synthesized using Cymbopogon citratus (Poaceae …
Encapsulation of aceclofenac hydrogel-based solid dispersion for sustained delivery
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Calister E. Ugwu, Kingsley Eze
Purpose: To develop aceclofenac hydrogel-based solid dispersions (AC-HSDs) encapsulated in two modified gelatin capsules (MGCs as MGX1 and MGX2) for sustained drug delivery.Methods: The AC-HSDs …
Behavioural alterations and cerebellar toxicity induced by Datura metel exposure in mice
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Vincent-Junior Onoriode Igben, Enaohwo Taniyohwo Mamerhi, Emmanuel Agbamu
Purpose: To investigate the neurotoxic effects of methanolic crude extract of leaves of Datura metel L. Solanaceae on the cerebellum and motor coordination.Methods: A total …
A Historical Analysis of Gender Discrimination in the Johane Marange Apostolic Church
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Ezekiel Baloyi, Chiratidzo Zvashura
This paper presents a historical analysis of gender discrimination within the Johane Marange Apostolic Church, with a focus on its headquarters in Manicaland Province, Zimbabwe. …
Financial Sector Development, Institutional Quality and Environmental Degradation in Namibia
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Brigitte Fikunawa, Syden Mishi
Background Environmental degradation, which is the deterioration of ecological quality due to increased unsustainable economic activities, is a global concern that poses a threat to …
Antimicrobial Resistance (AMR) in Low-Resource Settings: A Molecular And Public Health Investigation Into the Role Of Environmental Reservoirs And Over-The-Counter Antibiotic Use In South-South Nigeria
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Chinaza Gloria Diala, O. Edobor, Pascaline David Edim
Antimicrobial resistance (AMR) is a significant public health challenge worldwide, particularly in underserved communities where access to healthcare is limited. Researchers are increasingly recognising that …
Effective and ineffective academic writing support for ESL students: A higher education perspective
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Ntshimane Elphas Mohale
Academic writing presents significant challenges for students who use English as a second language, often affecting students’ academic performance and progress. Given its critical role …
An analysis of grade 6 English first additional language reading comprehension questions in CAPS-aligned examinations
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Lucy Sibanda
Reading comprehension, a crucial skill for successful text interaction, remains a significant challenge for many South African learners, as evidenced by their persistent difficulties in …
Healing in the name of Jesus: A theological study of charismatic speech and ontological change
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Anna Cho
This article explores the performative utterance ‘in the name of Jesus’ within the framework of speech act theory, proposing the theological model E = hF(p). …
Determinants of Farmers’ Willingness to Adopt Organic Agriculture: Behavioural Insights and Systemic Challenges
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Gabriel Adewunmi Eyinade, Abbyssinia Mushunje, Shehu Folaranmi Gbolahan Yusuf
The environmental and health-related challenges associated with intensive and conventional farming practices have underscored the urgency of transitioning towards more sustainable agricultural systems, such as …
Assessing the prevalence of antimicrobial resistance among pediatric patients at Kamuzu Central Hospital, Malawi
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Agness Chisomo Chitedze, Rizine Mzikamanda, Tarsizio Maida
INTRODUCTION: Severe bacterial infections cause significant disease burden in developing countries, including Malawi. The situation is compounded by the scarcity of resources, inconsistent availability of …
The Barriers and Facilitators Impacting the Implementation of Curriculum Reforms in Higher Education for Sustainability
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Thivhavhudzi Muriel Badugela
The escalating global youth unemployment rate, coupled with limited exposure to entrepreneurship education, exacerbates socio-economic challenges. This study thus explored how cultivating entrepreneurial mindsets through …
Exploration of Social Cognitive Learning Theory: An Expedition to re-enact Gender-based Violence Prevention Strategies in Nigerian Secondary Schools
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Damilola Gbemisola Onaolapo, Sekitla Daniel Makhasane
This theoretical paper discussed the potential of social cognitive learning theory as an effective tool for re-enacting gender-based prevention strategies in Nigerian secondary schools. The …
Predicting cosolvents, surfactants and electrolytes as potential transdermal delivery enhancers of pantoprazole
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Chika John Mbah, Chinwe M. Onah, Sardauna Monde
Purpose: To predict cosolvents, surfactants, and electrolytes as potential enhancers of pantoprazole transdermal delivery by examining their effects on the drug's coefficient of partition. Methods: …
Development and characterization of Soluplus-based solid dispersion to improve solubility
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Ugwu Calister Elochukwu, Christopher Ugwoke
Purpose: To improve the solubility of lumefantrine (lum), using developed solid dispersions (SDs) with Soluplus and Kollidon VA 64, at various lum: carrier ratios to …
Optimising Pedagogical Approaches: Integrating Jigsaw as a Strategy to Overcome Learning Challenges for First-Year Students in Business Education at a University of Technology
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Lesang Grace Mogashoa
In this empirical study, the researcher discussed the challenges faced by first-year students in teaching and learning business education and how to enhance the challenge. …
Histopathological effects of D’General Bitters on the pancreas of male adult Wistar rats
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Darlington Nnamdi Onyejike, Ugochukwu Samuel Aguwa, AC Nwabueze
Purpose: To investigate the histopathological effect of D’General Bitters (a herbal drink) on the pancreas of adult male Wistar rats. Methods: Twenty male Wistar rats …
Entrepreneurship Education in Instilling an Entrepreneurial Mindset as an Alternative Towards Job Creation: A Systematic Literature Review
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Pulane Adelaide Molomo, Mochina Mphuthi, Nosiphiwe Mpiti
The escalating global youth unemployment rate, coupled with limited exposure to entrepreneurship education, exacerbates socio-economic challenges. This study thus explored how cultivating entrepreneurial mindsets through …