Willingness of adolescent girls and young women to participate in future clinical trials of long-acting PrEP implants for HIV prevention, Kampala Uganda
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Jane Frances Lunkuse, Grace Godfrey Sseremba, Candice Chetty-Makkan
Adolescent girls and young women (AGYW) continue to face a significant risk of HIV infection, particularly as numerous experimental prevention products are in development. This …
Malaria, urogenital schistosomiasis and co-infection and nutritional status of school children in Ondo state
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Esther Mofiyinfoluwa Ola, Temitope Helen Balogun, Rasheed Olayinka Isijola
Parasitic infections are a major cause of morbidity and mortality in Nigeria, with malaria and schistosomiasis having the highest burden. This study investigated the prevalence …
The impact of Schistosoma haematobium hybridization on molecular diagnosis of schistosomiasis: A review with emphasis on female genital schistosomiasis
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Ombeni Ally, Bernard N. Kanoi, Gideon Sadikiel Mmbando
Female genital schistosomiasis (FGS) is a gynecological manifestation of urinary schistosomiasis in female genitals. FGS is a neglected tropical disease; not only are most patients …
Improving pediatric care in Uganda with a digital platform and quality improvement initiative: A retrospective review of Smart Triage + QI
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Rebecca Goertzen, Yashodani Pillay, James Karugaba
OBJECTIVE: This is a retrospective review of the feasibility study and implementation of the Smart Triage and Quality Improvement (QI) initiative at Holy Innocents Children's …
Recrudescence of transmission of onchocerciasis in some endemic communities in Kaduna State, Nigeria: What is the way forward?
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Timothy O. Olanrewaju, Felicia N. C. Enwezor, Luret Lar
BACKGROUND: Onchocerciasis caused by the filarial parasite Onchocerca volvulus and transmitted by Simulium damnosum s.l. remains a public health concern in Nigeria. Infestation of S. …
Association between presence of latrine and unclean child face on the prevalence of active trachoma among children aged 1 to 9 years in low-income setting: A systematic review and meta-analysis
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Leykun Berhanu, Chala Daba, Belay Desye
BACKGROUND: Trachoma is the leading infectious cause of blindness worldwide, primarily affecting populations in low-income countries with poor sanitation and hygiene conditions. The World Health …
Carotid intima–media thickness and endothelial function in adolescents exposed to alcohol consumption and cigarette smoking in utero: a mediation analysis
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Tammy Charlene Hartel, Aamer Sandoo, A Oelofse
Abstract Background Previous studies have shown the effects of teratogen exposure in utero on the vascular system, but its direct and indirect effects are still …
Tropical infections and the gut microbiome: dysbiosis, recovery, and clinical implications
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Biruk Demisse Ayalew, Muhammad Umar, Muhammad Muddasar Saeed
The gastrointestinal (GI) microbiome, crucial for host health through its roles in digestion, immunity, and pathogen protection, is significantly disrupted by tropical infections. This disruption, …
Urticarial hypocomplementemic vasculitis syndrome and systemic lupus erythematosus: a case report and review of the literature
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Yasmina Ouerdani, Tayssir Ben Achour, Ahlem Ben Hmid
Background: Hypocomplementemic urticarial vasculitis (HUV) syndrome is a rare form of small-vessel vasculitis characterized by a heterogeneous spectrum of clinical and biological findings. It is …
Identifying the opportunities and barriers: a cross-sectional review of the health development coordination mechanisms in the World Health Organization African Region
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Abdulmumini Usman, Olushayo Oluseun Olu, Mohamed Kakay
Effective health sector coordination is essential to improve the implementation of development and humanitarian response programmes in the WHO African Region. In recent years, multiple …
Anthrax outbreak surveillance and response in Arba Minch, Ethiopia: After-action review
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Yaregal Fufa, Tsion Desalegn, Negash Abera
Background: Anthrax is a serious infectious disease affecting animals and humans and remains a public health issue in developing countries. Aim: This study assessed the …
Ethnopharmacological exploration and isolation of HIV-1 latency-reversing agents from Sudanese medicinal plants
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Khaled M. Elamin, Naoki Kishimoto, Teppei Kawahara
HIV-1 infection remains a major health challenge, especially in resource-limited settings such as Sudan, where traditional medicine is widely practiced for managing infectious diseases, including …
Spatial variation of correct knowledge of the ovulatory cycle and its associated factors among reproductive age women in Ethiopia: geographically weighted regression analysis
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Werkneh Melkie Tilahun, Lamrot Yohannes Abay, Fantu Mamo Aragaw
Background: Information about reproductive physiology like the ovulatory cycle helps women to understand their pregnancy risk and appropriately plan their pregnancies, which can reduce unintended …
Confirmation of a hyperendemic focus of porcine cysticercosis in Northern Uganda: Prevalence and risk factor analysis
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Nicholas Ngwili, Salaviriuse Ahimbisibwe, Max Korir
BACKGROUND: Taenia solium (T. solium), a neglected zoonotic tapeworm transmitted between humans and pigs, is a leading cause of acquired epilepsy in endemic areas where …
Computer aided greenness by design approach for resolving and quantifying Triamterene and Hydrochlorothiazide in pharmaceutical mixtures employing multiscale dynamics simulations
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Ahmed Elsonbaty, Khaled Attala, Eman Darweish
In this study, we present an established approach for the UV spectroscopic determination of Hydrochlorothiazide and Triamterene in pharmaceutical mixtures, leveraging the principles of Greenness-by-Design …
Optimizing safe rates of pop-up inorganic starter nitrogen and potassium fertilizers for maize
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William Makaza, Lotfi Khiari, Mounir El Achaby
Applying starter nitrogen (N) and potassium (K) fertilizers in a pop-up placement directly in the maize seed furrow is a delicate practice due to the …
Evaluation of multisectoral interprofessional collaboration for non-communicable disease management within a municipal setting: a mixed methods study
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Salomey Asaah Denkyira, Kwaku Gyamfi Oppong, Daniel Boateng
BACKGROUND: Strengthening multisectoral collaboration is essential for NCD prevention and control. In Ghana, the healthcare system often experiences inefficiencies due to fragmented care pathways and …
Prevalence and antimicrobial susceptibility of gram-negative bacteria in the urine of females in their reproductive ages in the Tamale Teaching Hospital
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Rashida Ibrahim, Abudu Ballu Duwiejuah, Kennedy Mensah Osei
Regardless of where the illness occurs in the urinary tract, a urinary tract infection (UTI) is defined as the presence of substantial bacteria in urine. …
The Role of Output Monitoring and Review on Teacher Job Performance in Secondary Schools: Evidence from Kasese District, Uganda
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Asiati Mbabazi, Zulaiha Lawal Bagiwa, Tukur Muhammad
Background: Teacher job performance is an important factor influencing the quality of education and student learning outcomes. Effective output monitoring and review ensure teachers adhere …
AI and mission: Answers to questions on mission to AI and evaluation of the replies
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Pieter Verster
Artificial intelligence (AI) has implications for all aspects of science, including the science of mission. However, the dangers of AI are also obvious, namely lack …