Critical thinking development in a Quality Matters-based online learning: student insights from a South African higher education context
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Nusirat Ojuolape Gold, Husain Coovadia, Tasneem Mahmood
Introduction The transition in learning mode from traditional systems to online modes is attracting continuous attention globally. For quality assurance, universities are increasingly adopting online …
An efficient machine-learning framework for predicting protein post-translational modification sites
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Heba M. Elreify, Fathi E. Abd El‐Samie, Moawad I. Dessouky
Post-Translational Modifications (PTMs), particularly lysine 2-hydroxyisobutyrylation (Khib), represent critical regulatory mechanisms governing protein structure and function, with mounting evidence underscoring their important implications in cellular …
Mycofabrication of sustainable mycelium-based leather using Talaromyces sp. and irradiated eggplant peel waste
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Reham M. M. Abdelkader, Ola M. Gomaa
Agro-industry and leather manufacturing are considered two of the most polluting industries worldwide due to the huge amount of waste they produce that contributes to …
Inter-epidemic seroprevalence of Rift Valley fever virus and associated risk factors in humans in Eastern Rwanda
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Isidore Nsengimana, David J. Kelvin, Evodie Uwibambe
BACKGROUND: Rift Valley fever (RVF) is a mosquito-borne zoonosis that causes periodic and explosive epizootics/epidemics in Africa and the Arabian Peninsula. In Rwanda, RVF virus …
Effectiveness and challenges of digital tools implementation for enhancing infectious disease surveillance data quality in low- and middle-income countries: A systematic review protocol
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Oluwatosin Olu-Abiodun, Aderinsola Faturoti, Akinmade Adepoju
BACKGROUND: Monitoring infectious diseases is essential for preventing and controlling outbreaks, especially in low- and middle-income countries (LMICs), where issues like poor infrastructure, lack of …
Genomic epidemiology of enteropathogenic Escherichia coli in southwestern Nigeria
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Olabisi C. Akinlabi, Rotimi Ayodeji Dada, Ademola Adetayo Olayinka
BACKGROUND: Enteropathogenic Escherichia coli (EPEC) are etiological agents of diarrhea. We studied the genetic diversity and virulence factors of EPEC in southwestern Nigeria, where this …
Predicting neonatal mortality using ensemble machine learning algorithms in the case of Ethiopian Rural Areas
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Melaku Alelign Mengstie, Misganaw Telake Telele
Abstract Background Each year, approximately 2.5 million newborns die globally, with developing countries bearing the impact of this crisis. Sub-Saharan Africa has the highest neonatal …
Rice production in Ghana: a multi-dimensional sustainable approach
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Andrews Danso Ofori, John Kwame Titriku, Xing Xiang
Rice is a vital crop in Ghana, contributing 15% to the country’s Gross Domestic Product (GDP). However, rice production in the country faces significant challenges, …
Factors associated with the acceptability of self-injection training by clients receiving DMPA-SC services from community pharmacies and patent and proprietary medicine vendors in Nigeria
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Toyin Akomolafe, Emeka Emmanuel Okafor, Sikiru Baruwa
BACKGROUND: The self-administration of the subcutaneous depot medroxyprogesterone acetate (DMPA-SC) has the potential to empower women and improve contraceptive use. Several studies have demonstrated the …
The potential impact of declining development assistance for health on population health in Malawi: A modelling study
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Margherita Molaro, Paul Revill, Martin Chalkley
BACKGROUND: Development assistance for health (DAH) to Malawi will likely decrease as a fraction of Gross Domestic Product (GDP) in the next few decades. Given …
Proximate composition, fiber fractions, techno-functional and pasting properties of wheat and African palmyra palm shoot composite flours and acceptability of their developed chin-chin snacks
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Rowland M. O. Kayode, Bashirat Romoke Ajibade, Sarafa Adeyemi Akeem
Abstract African palmyra palm (Borassus aethiopum Mart.) is an underutilized plant indigenous to tropical Africa and its shoot which is usually eaten raw or cooked …
Chemical profile of essential oil from Pimenta racemosa leaves, antioxidant potential, and its enzyme inhibitory properties
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Omayma A. Eldahshan, Nilofar Nilofar, Gökhan Zengin
Pimenta racemosa var. recemosa (Mill.) J. W. Moore is an aromatic plant belonging to the family Myrtaceae, native to Venezuela, Puerto Rico, and Jamaica and …
‘Better she gets infected by other diseases but not pregnancy’. Narratives from adolescent girls and community males following pregnancy escalation during COVID-19 lockdown
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Linda Mason, Enid Awiti, Sophie Young
Introduction: Adolescent sexual and reproductive health in low- and middle-income countries is critical to address following the COVID-19 pandemic. Growing evidence of its' impact includes …
Cultural, economic, and settlement shifts over the last 9,000 years at Kakapel Rockshelter, Western Kenya
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Steven T. Goldstein, Natalie G. Mueller, Emma M. Finestone
The spread of food production in sub-Saharan Africa involved multi-directional dispersals of domesticated plant and animal species, often associated with major migrations. The Lake Victoria …
Age-structured malaria model with temperature-dependent dynamics and optimal control analysis within a partial differential equation framework
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Lukas Degu Petros, Temesgen Erena Abdisa, Dinka Tilahun Etefa
Malaria remains a significant global health challenge, particularly in sub-Saharan Africa, despite advances in control measures. In 2023, there were an estimated 263 million malaria …
Nurse leaders' perceptions of leadership development needs for strengthening the nursing workforce: a South African pilot study
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Mirriam Matandela, Goitsemang Lucy Chisale, Vhothusa Edward Matahela
Background Nurses are central to South Africa's healthcare system, yet the sector faces ongoing challenges, including workforce shortages, high workloads, limited career progression, and weak …
MAPK-targeted therapies in non-gastrointestinal stromal tumor soft tissue sarcomas: current landscape and future directions
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Ouissam Al Jarroudi, Khalid El Bairi, Sami Aziz Brahmi
Non-Gastrointestinal Stromal Tumors (Non-GIST) Soft Tissue Sarcomas (STS) are highly aggressive and challenging diseases with poor prognosis and limited therapeutic options. Molecular profiling is urgently …
Bat-human interactions and associated factors among communities in Bundibugyo District, Uganda: A cross-sectional study
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James Natweta Baguma, Shamilah Namusisi, Lesley Rose Ninsiima
More than 70% of new, emerging, and reemerging infectious diseases are from animal origin. Human interaction with bats has been associated as a driver for …
Utility of 3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde in the synthesis of novel 1,3,4-thiadiazoles or 1,3-thiazoles and study their cytotoxic activity
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Anhar Abdel‐Aziem, Abdou O. Abdelhamid
Abstract One of the biggest causes of death around the world is cancer. Despite the development of a variety of chemotherapeutic drugs that stop excessive …
Coating silicon catheters with the optimized and stable carotenoid bioproduct from Micrococcus luteus inhibited the biofilm formation by multidrug-resistant Enterococcus faecalis via downregulation of GelE gene expression
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Khaled B. Al-Monofy, Ahmed Abdelaziz, Amal M. Abo-Kamar
Abstract Background Microbial carotenoids have gained industry interest due to their safety and diverse biological activities; however, the low yield of carotenoids hinders their applications. …