Validation of stool and blood analysis compared to Inv A and ttr based direct blood qPCR assay as diagnostic tools for typhoid fever
Article scientifique
Accès ouvert
Shymaa Abdelsattar Elaskary, Hanem Mohamed Badawy, Doaa Salah Elgendy
BACKGROUND: The development of molecular techniques, such as polymerase chain reaction (qPCR), provides a promising approach for detecting S. enterica due to its rapidity, sensitivity, …
Genetic analyses and molecular associations of FSHR and GH genes for semen traits in Egyptian buffalo
Article scientifique
Accès ouvert
Abdelfatah R Zaghloul, M. H. Khalil, M. M. Iraqi
Abstract Background & objectives The reproductive efficiency of buffalo bulls is crucial for genetic improvement, herd fertility, and overall productivity. Identifying genetic markers linked to …
Business growth mentorship for female-owned enterprises in South Africa
Article scientifique
Accès ouvert
Karabo Lekoloane, Anastacia Mamabolo, Gloria Mbokota
Purpose: This study examines the role of mentorship offered to female entrepreneurs during the growth phase of their businesses. Applying social cognitive theory (SCT), we …
Predictors of glycemic control, quality of life and diabetes self-management of patients with diabetes mellitus at a tertiary hospital in Ghana
Article scientifique
Accès ouvert
Kwadwo Faka Gyan, Enoch Agyenim‐Boateng, Kojo Awotwi Hutton‐Mensah
BACKGROUND: The burden of diabetes mellitus (DM) in Sub-Saharan Africa is high and continues to increase. Effective DM management focuses on key goals such as …
Aedes aegypti ecology and dengue infection in three agricultural areas of Côte d’Ivoire
Article scientifique
Accès ouvert
Edwige M A Y Kadjo, Sylla Yahaya, Négnorogo Guindo‐Coulibaly
BACKGROUND: Over the last ten years, there has been an upsurge of dengue outbreaks in Côte d'Ivoire, with Aedes aegypti as the principal vector. The …
VISTA is a potential target for immunotherapy in B-cell acute lymphoblastic leukemia in children
Article scientifique
Accès ouvert
Nourhan Hossam Eldin Mohamed, Mohamed A. El‐Mokhtar, Asmaa M. Zahran
Abstract Immune checkpoints expressed by immune cells are critical mediators of immune suppression in cancer. Recently, the role of VISTA, an immune checkpoint, in suppressing …
Strengthening governance and leadership of the national laboratory system in Liberia: achievements and challenges
Article scientifique
Accès ouvert
Torbandu H Kohar, Ellen Munemo, Jonathan Kpaka
Background: Liberia's health system, severely impacted by prolonged conflict and the 2014-2015 Ebola outbreak, suffered from critical gaps in laboratory governance, workforce capacity, and diagnostic …
Drivers of antimicrobial resistance in pig production systems of Uganda
Article scientifique
Accès ouvert
Adrian Muwonge, Tadeo Kakooza, P. Johnson
Abstract Increasing protein demand in low- and middle-income countries may accelerate livestock intensification, antibiotic overuse and antimicrobial resistance (AMR) risk. Here, we examined Uganda’s growing …
Socioeconomic inequality for hypertension among reproductive age women aged 15–49 from five Sub-Saharan Africa countries: A decomposition analysis of DHS Data
Article scientifique
Accès ouvert
Daniel Bekele Ketema, Desalegn Markos Shifti, Teketo Kassaw Tegegne
Hypertension is a significant public health issue in sub-Saharan Africa, especially among reproductive-aged women. This study aims to assess and decompose socioeconomic inequalities in hypertension …
Treatment outcomes of multi-drug-resistant and rifampicin-resistant tuberculosis with and without isolation of nontuberculous mycobacteria between 2018–2021: A retrospective cohort study in Ghana
Article scientifique
Accès ouvert
Elizabeth Tabitha Abbew, Roger Laryea, Ama Owusuaa Kwakye
Multi-drug-resistant and rifampicin-resistant tuberculosis (MDR/RR-TB) pose an urgent health threat in Ghana. Despite ongoing interventions, the outcomes for MDR/RR-TB in Ghana have remained suboptimal over …
Optimized Model Predictive Control for improving dynamic stability and steering accuracy in multi-axle cranes
Article scientifique
Accès ouvert
Abdulhakeem Muhammed Ali, Yusuf Abubakar Sha’aban, Ahmed Tijani Salawudeen
The multi-axle crane, a long vehicle with high inertia, has historically struggled with steering efficiency and path-tracking performance. Various control strategies, including Proportional-Integral-Derivative (PID), Linear …
A conceptual framework for inclusive participation in communal land development: feminism perspective
Article scientifique
Accès ouvert
Hlengiwe Patronella Zulu, Themba Mfanafuthi Lukhele, Primrose Thandekile Sabela
Participatory community development is considered as one of the important mechanisms of governance in ensuring inclusive and people centered development in emerging economies around the …
Common sources, perceived communication efficacy and sufficiency of cervical cancer information, education and communication materials for women with HIV/AIDS in rural Kenya
Article scientifique
Accès ouvert
Scholastic Adeli, Omenge Orang’o, Violet Naanyu
Introduction Cervical cancer is the greatest cause of cancer-related death among women in Sub-Saharan Africa, with particularly high incidence and mortality rates in rural regions. …
Opportunity for cost savings with a novel differentiated model of PrEP delivery: a comparative costing analysis of six-month PrEP supported by interim HIV self-testing and standard of care PrEP dispensing in Kenya
Article scientifique
Accès ouvert
Dorothy I. Mangale, Jesse Heitner, Katrina F. Ortblad
BACKGROUND: Cost remains an important barrier to HIV pre-exposure prophlyaxis (PrEP) delivery in Africa. Simplified delivery models that reduce costs without compromising PrEP outcomes are …
Awareness campaigns and strengthened prevention as alternatives to banning: Preventing zoonotic diseases from wildlife in the Democratic Republic of Congo
Article scientifique
Accès ouvert
Marc Kapenga Yambayamba, Chloe Clifford Astbury, Hélène Carabin
BACKGROUND: The Democratic Republic of Congo (DRC) faces a rising frequency of emerging infectious diseases outbreaks such as Ebola and Mpox. Wild meat consumption is …
The status of occult HBV infection in a high endemic region: risk of community HBV transmission and reactivation
Article scientifique
Accès ouvert
Hussein Mukasa Kafeero, Ponsiano Ocama, Dorothy Ndagire
OBJECTIVES: Occult hepatitis B virus (OBI) infection, characterized by the presence of HBV DNA in the absence of detectable HBsAg in the blood, is considered …
Ancient and dominant: a novel feline immunodeficiency virus subtype “X-EGY” identified in Egyptian cats associated with high prevalence
Article scientifique
Accès ouvert
Mahmoud S. Safwat, Amany Dieb Bahr, Noha M. Bakry
BACKGROUND: Data on the epidemiology and molecular characterization of feline immunodeficiency virus (FIV) in Egypt are limited. This study aimed to estimate FIV prevalence in …
Dynamic shift of malaria cases in northwest Ethiopia: a 10-year retrospective cohort data analysis from 2012 to 2021
Article scientifique
Accès ouvert
Aberham Abere, Solomon Mekuriaw Ayalew, Bealemlay Wondale
Background Despite the WHO’s extensive efforts to eliminate malaria from sub-Saharan Africa, including Ethiopia, it remains the most serious public health issue, with seasonal variations …
Youth at the crossroads: balancing contributions to conflict and peace amid high unemployment in Africa
Article scientifique
Accès ouvert
Daniel Chigudu
Over 60% of young people in Africa are unemployed, creating a serious youth unemployment issue that exacerbates instability and limits peacebuilding chances. The variables that …
Evaluating lowland coffee genotypes against leaf rust and wilt diseases in southwestern Ethiopia
Article scientifique
Accès ouvert
Hailu Negesa, Gabisa Gidisa, Zenebe Wubshet
Introduction: , are major limiting factors of coffee production. However, Ethiopia has not yet reported a commercialized resistant variety for both of these diseases. Therefore, …