Decentralization of diagnosis and management of skin diseases at primary hospitals in southern Ethiopia
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Dagimawie Tadesse, Mehret Techane Woge, Saskia van Henten
Impact of Integrated Malaria Control Interventions: A Comparative Analysis of Pre- Intervention, Post-Intervention, and Combined Intervention Approaches in Rural and Urban settlement Southeastern Nigeria
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John Iwunze
Time to first and recurrent missed video directly observed therapy sessions and associated factors among people with Tuberculosis in Kampala, Uganda
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Kelvin Bwambale, Drake Amutuheire, Damalie Nakkonde
Background: Video Directly Observed Therapy (VDOT) provides a promising alternative to in-person directly observed therapy (DOT) for Tuberculosis (TB) treatment adherence monitoring. However, sustained patient …
New thinking for the next generation of antimalarials
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Hannah Asiki, Jason Hlozek, Kathryn J. Wicht
Despite decades of intensive research and substantial clinical gains, malaria remains a major global health challenge exacerbated by the continued emergence of drug-resistant strains of …
PARP inhibitors across different malignancies: clinical applications, resistance mechanisms, and strategies to enhance efficacy through combination therapies
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Abdelhak Ouhajjou, Omayma Mazouji, Chakib Nejjari
Poly-ADP-ribose polymerase (PARP) inhibitors represent a novel class of anticancer agents that leverage the principle of synthetic lethality to induce tumor cell death by disrupting …
Do Social Safety Nets Buffer the Nutritional Effects of Drought? A Longitudinal Study of Children in Ethiopia
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Diana Najarro, Jasmin Ghany, Asya Dimitrova
Relationship between lower urinary tract symptoms and erectile function in men aged over 40 years in Brazzaville, Republic of the Congo
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Ghidmar Onguélé-Okemba, Yannick Ijosdi Dimi Nyanga, Roland Bertile Banga-Mouss
Abstract Background Lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) are common conditions in men over 40 years and significantly impair quality of life. …
The biological screening of aromatic medicinal plant extracts for their potential in vitro bioactivity against factors associated with breast mastitis
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Elizabeth Jean Wildy, Samantha Rae Loggenberg, Namrita Lall
Breast mastitis is an inflammatory condition caused by pathogenic infection, which is usually treatable with antibiotics, yet there is a lack of research focusing on …
Economic and livelihood conditions of women community health workers in Ethiopia: implications for workforce sustainability—a mixed-methods study
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Geteneh Moges Assefa, Wasihun Andualem Gobezie, Tiruminch Yimer
Does education improve managers' use of thinking skills during creative problem-solving? A moderation analysis
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Mpumelelo Longweni
Without effective problem-solving (EPS), along with divergent thinking (DT) and convergent thinking (CT) skills, managers’ creative problem-solving process (CPS) may be rendered deficient. Their efforts …
Flywheel Energy Storage System for Regenerative Braking and Enhanced Stopping Performance in Vehicles
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Mohamed A. Mosbah, Ahmed Abokhalil, Khairy Sayed
Plant-food components at the microbiota–neuroinflammation interface: human evidence, translational limits, and sustainable dietary translation
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Kingsley Excel Dunga, Sylvester Chibueze Izah, Afamefuna Dunkwu-Okafor
This narrative review evaluates how convincingly plant-food components and plant-rich dietary patterns influence neuroinflammation and whether those mechanisms translate into neurological benefit. Infection is treated …
When data lie: correcting a conflict variable reverses a significant finding in Chad's agricultural time series (1961–2024)
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Abderamane Mahamat Abdel-Aziz
Effect of a person-centered care intervention on return and sustained reengagement after treatment interruptions from HIV care in Zambia: A post-hoc analysis of a stepped-wedged cluster randomized trial
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Aaloke Mody, Kombatende Sikombe, Sandra Simbeza
BACKGROUND: Poor client-provider interactions lead to reinforcing cycles of treatment interruptions (TIs) from HIV care and fear of return, undermining sustained retention. We previously demonstrated …
AI-enabled D-dimeromics in precision breast oncology: a transformative framework for the identification, stratification, and prognostication of ultra-high-risk disease phenotypes
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Emmanuel Ifeanyi Obeagu
Breast cancer is a highly diverse ailment marked by various molecular subtypes, differing clinical paths, and unique treatment reactions. Notwithstanding considerable progress in precision oncology, …
Abundance of Indian Ocean humpback dolphins (Sousa plumbea) along the Garden Route of South Africa
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W. Chris Oosthuizen, Stephen P. Kirkman, Danielle S. Conry
Human development is placing growing pressure on coastal ecosystems worldwide. Coastal dolphins are consequently exposed to a range of anthropogenic threats, yet for many species, …
A Hybrid Machine-Learning Based Security Algorithm for Improved Detection of Distributed-Denial-of-Services Attacks in Internet of Things Networks
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Coster Baloyi, Topside E. Mathonsi, Tshimangadzo M. Tshilongamulenzhe
Scope 3 Emissions Tracking and Circular Supply Chain Performance, the Mediating Role of Supplier Sustainability Collaboration and Moderating Influence of Data Transparency
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Abdul-Basit Danjoe Munkaila, Abdul-Aziz Mustapha, Adam Sandow Saani
On-treatment and early post-radiotherapy EBV-DNA dynamics in locoregionally advanced nasopharyngeal carcinoma: a systematic review
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Imad Barjij, Sarah Naciri, Sihame LKHOYAALI
Background: Plasma Epstein-Barr virus DNA (EBV-DNA) is an established prognostic biomarker in nasopharyngeal carcinoma (NPC).While baseline EBV-DNA reflects tumour burden, increasing interest has focused on …
Leishmania infantum eukaryotic initiation factor 4A modulates in vitro functional activity of human neutrophils
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Rafeh Oualha, Yosser Zina Abdelkrim, Mourad Barhoumi
Leishmaniases are a group of neglected tropical diseases caused by Leishmania parasites which virulence mainly relies on its modulation of the host immune response. Neutrophils, …