440 publication(s) trouvée(s)
Article scientifique
Phytochemical Analysis and Apoptosis-Inducing Anticancer Activity of Buddleja polystachia Leaf Extract against HeLa Cell Lines
OBJECTIVE: Cervical cancer is the second leading cause of mortality in women globally, with its incidence increasing due to multidrug …
Article scientifique
HPV Self-Sampling for Cervical Cancer Screening in Morocco: A Cross-Sectional Study
OBJECTIVE: Morocco is currently planning to introduce HPV testing as the primary screening method in routine cervical cancer screening. Accordingly, …
Article scientifique
Breast Cancer Screening in Tunisia: A Cross-Sectional Study on Women’s Knowledge, Attitudes and Practices
INTRODUCTION: In Tunisia, the incidence and mortality rates of breast cancer are relatively high and are projected to remain a …
Article scientifique
Molecular Insights into the Immunomodulating and Anticancer Mechanisms of Eremina desertorum (Forsskal, 1775) Mucin in HepG-2 and CACO-2 Cells
BACKGROUND: The aim of the present research is to deeply investigate the cytotoxic and immunomodulatory activities of the mucin extracted …
Article scientifique
Prognostic Significance of miR-145, NANOG, OCT4, and KLF4 in Triple-Negative Breast Cancer
BACKGROUND: Among women, breast cancer is the leading cause of cancer-related deaths. OCT4, NANOG, and KLF4 are markers of cancer …
Article scientifique
Molecular Mechanisms of FAT Atypical Cadherin 1 (FAT1), the Hippo Pathway, and the Yes-Associated Protein (YAP) Signaling Pathways in Some Cancers
Introuduction: FAT atypical cadherin 1 (FAT1), the Hippo pathway and Yes-associated protein (YAP) signaling play significant roles in cell proliferation, …
Article scientifique
Schlafen 11 (SLFN11) And Tumor-Infiltrating Lymphocytes (TILs): Dual Predictive Biomarkers In Ovarian Serous Carcinoma
OBJECTIVES: This study aims to investigate the clinicopathological significance and prognostic impact of SLFN11 expression and tumor-infiltrating lymphocytes (TILs) in …
Article scientifique
Crosstalk between ZEB1 expression and CD163+ Tumor-Associated Macrophages in Muscle-Invasive Urothelial Carcinoma
OBJECTIVE: There is an urgent need to investigate the molecular mechanisms underlying the invasion and metastasis of bladder cancer to …
Article scientifique
The Relationship between SALL4 and Fascin Expression and the Progression of Colorectal Carcinoma
OBJECTIVE: SALL4 (Spalt-like transcription factor 4) is a stem cell transcription factor that is reactivated in various tumor tissues and …
Article scientifique
Identification of BRCA1 and BRCA2 Germline Mutations in Female Breast Cancer Patients Using Next Generation Sequencing
BACKGROUND: Breast cancer is the most common cancer affecting females according to WHO 2020 report, with BRCA1 and BRCA2 identified …
Article scientifique
Clausenidin from Clausena excavata Burm. causes Apoptosis of Liver Cancer in Mice
BACKGROUND: Clausenidin is a pyranocoumarin that was isolated from the roots of Clausena excavata Burm. Previously, the pure clausenidin crystals …
Article scientifique
Exploring the Role Of CD155 in Urothelial Carcinoma of the Urinary Bladder: An Immunohistochemical Study & Its Correlation With PD-L1
BACKGROUND: Urinary bladder carcinoma is one of the most immunogenic cancers. Several immune checkpoint inhibitors targeting programmed death-ligand 1 (PD-L1) …
Article scientifique
Predictors of Secondary Traumatic Stress among Oncology Nurses in Palestine
INTRODUCTION: The work environment of oncology nurses exposes them to patient suffering, making them vulnerable to developing Secondary Traumatic Stress …
Article scientifique
Analysis of Risk Factors and Assessment of miRNA-122 as a Novel Biomarker for Colon Cancer in Egyptian Patients
BACKGROUND: Colon cancer is one of the most prevalent cancers in the world; some of its risk factors are controllable. …
Article scientifique
Prognostic and Predictive Significance of Cancer Stem Cell Markers (ZIP-4 and ALDH1A1) in Ovarian Serous Carcinoma Patients: An Immunohistochemical Study
BACKGROUND: Worldwide, ovarian cancer is the eighth most common cancer among females and the fifth leading cause of cancer-related deaths …
Article scientifique
Monte Carlo Investigation of Field Size Effects on Central-Axis Dose Distributions (PDD Curves) and Lateral Dose Profiles
INTRODUCTION: After radioactivity and X-rays were first discovered, researchers found that radiation could harm cells by damaging their internal structures, …
Article scientifique
The Clinical Relevance and Prognostic Significance of Calcitonin Receptor-Like (CALCRL) Gene Expression in AML Patients
The outcome of acute myeloid leukemia (AML) is heterogeneous, with both patient-related and disease-related factors contributing to an individual patient's …
Article scientifique
Unraveling Key Regulatory Pathways in Non-HCV-Induced Hepatocellular Carcinoma: Insights from Exclusively Mutated Genes and Prognostic Biomarkers
BACKGROUND: The molecular pathogenesis of hepatocellular carcinoma (HCC) exhibits striking etiological heterogeneity, with non-HCV-associated cases representing an increasingly prominent clinical …
Article scientifique
Isolation and Characterization of Superoxide Dismutase from Tectus dentatus Marine Snail with Antimicrobial and Antitumor Activities
OBJECTIVE: The aim of this study is to reports the purification, biochemical characterization, and biological activities of superoxide dismutase (SOD) …
Article scientifique
A Survival Analysis of Pediatric Acute Lymphoblastic Leukemia in Morocco
BACKGROUND: As a WHO's Global Initiative for Childhood Cancer pilot site, Morocco conducted a study on the overall survival rates …