440 publication(s) trouvée(s)
Article scientifique
Evaluation of CD20-Positive B Cells in Libyan Lymphoma Patients Following Rituximab Treatment
OBJECTIVE: To monitor the depletion of CD20-positive B cells in Libyan lymphoma patients treated with Rituximab using flow cytometry. METHODS: …
Article scientifique
Expression of Interleukin 23 and Interleukin 28 in Mucinous & Non-Mucinous Colorectal Carcinoma and Their Relation to Clinicopathological Features and Prognosis
INTRODUCTION: Interleukin (IL)-28, a type III interferon related to the IL-10 family, shares multiple structural and functional characteristics with IL-22, …
Article scientifique
MUC4 and Caspase-3 Immunoexpression in Meningioma: A Histopathological Study Linking Mucin & Apoptotic Pathways
BACKGROUND: The most frequent intracranial primary tumors of the central nervous system and the second most frequent tumors of the …
Article scientifique
Expression of Programmed Death-1 Ligands (PD-L1 and PD-L2) in Endometrial Carcinoma: Immunohistochemical Study
BACKGROUND: On basis of knowledge about the relationship between the immunity and cancer; cancer immunotherapies were introduced. Immune checkpoint regulators …
Article scientifique
Oxidative Stress Dynamic among Helicobacter pylori-Positive Patients with Various Stages of Premalignant Histologic Lesions: A Prospective Study in Cameroon
OBJECTIVE: This study sought to evaluate biomarkers of oxidative stress among H pylori infected patients in relation to neoplastic transformation …
Article scientifique
Human Papillomavirus (HPV) Vaccination and Cervical Cancer Prevention: Ghanaian Adolescent Students’ Perspectives Through Focus Group Discussion
BACKGROUND: The Human Papillomavirus (HPV) vaccine is effective in reducing HPV-related cancers. However, little is known about Ghanaian adolescents' attitudes …
Article scientifique
Association of IFNL4 and IFITM3 Genetic Variants with Susceptibility to HCV-Related Liver Cirrhosis and Hepatocellular Carcinoma
OBJECTIVE: To ascertain the possible association of IFITM3 rs12252 and IFNL4 rs12979860 genetic polymorphisms with cirrhosis and HCC in chronic …
Article scientifique
Determinants of Diagnosis Delay in a Sample of Breast Cancer Patients from the Mohammed VI Centre for Cancer Treatment
BACKGROUND: Breast cancer (BC) is the most common type of cancer in women; a delayed diagnosis of BC is associated …
Article scientifique
Radiotherapy Improves Antitumor Immunity by Inducing Immunogenic Cell Death in Breast Cancer Patients
BACKGROUND: Radiotherapy, a significant cancer treatment, stimulates localized tumor cell death and causes immune modulation. Increasing data has indicated that …
Article scientifique
Survival and Prognostic Determinants after IMRT and 3D Radiotherapy in Metachronus Bone – Only Spinal Metastasis of Breast Cancer: A Prospective Phase II Trial
OBJECTIVES: Oligometastasis is a distinctive subset of osseous metastatic breast cancer, represented by single or few detectable metastatic osseous lesions. …
Article scientifique
Impact of Chronic Stress and Anxiety on Interleukin-6, Hypoxia-Inducible Factor-1α and on Pathological and Immunohistochemical Parameters in Breast Cancer
OBJECTIVE: The Aim of this study is to evaluate stress and anxiety by rating scale in breast cancer (BC) patients …
Article scientifique
Prognostic Value of PKM2 Expression in de novo Metastatic Colorectal Cancer Patients
BACKGROUND: Metastatic colorectal cancer (CRC) is considered one of the lethal neoplasms globally. The embryonic M2 isoform of pyruvate kinase …
Article scientifique
In Vitro Anticancer Activities of Senna singueana Leaf Extracts against HeLa Cell Lines
OBJECTIVE: The present demonstrated that SSL-CH extract selectively inhibits the growth of HeLa cell lines though activation of p53 and …
Article scientifique
Expression of Long Non-Coding RNA-NEAT-1 in Papillary Thyroid Carcinoma in Relation to Immunohistochemical expression of CD8 and PD-L1 as Indicators of Tumor Immune Microenvironment
OBJECTIVE: Investigation of CD8 and PD-L1 immunohistochemical expression, as indicators of tumor microenvironment in PTC, and their correlation with lncRNA-NEAT1 …
Article scientifique
Factors Influencing Patient and System Delays in Women with Breast Cancer in Morocco: A Systematic Review
OBJECTIVE: In Morocco, Breast cancer is the most common cancer in women. In most cases, the disease is confirmed at …
Article scientifique
Association of Interleukin-27 (IL-27) rs181206 T/C and rs17855750 T/G Gene Polymorphisms and the Risk of Hepatitis B Infection among Egyptians
BACKGROUND AND OBJECTIVE: HBsAg incidence in Egypt is at a range of 2 to 7%. Antiviral immunity is linked to …
Article scientifique
Investigation of the Effects of B7H4 (rs10754339 A>G) Gene Polymorphism and Serum Level on Breast Cancer Susceptibility
BACKGROUND: The prevalence of breast cancer groups requires further clarification to understand the mechanisms leading to its development. B7H4 is …
Article scientifique
Role of Circulating ARID1A mRNA as a Potential Biomarker in Female Breast Cancer Patients
BACKGROUND: Early diagnosis of breast cancer is crucial for successful management and better disease outcomes. Using blood samples as a …
Article scientifique
Predictive and Prognostic Significance of Serum Neuron-Specific Enolase in Patients with Metastatic Non-Small Cell Lung Cancer Receiving Gefitinib: A Prospective Study from South Egypt Cancer Institute
BACKGROUND: Lung cancer remains the most lethal cancer in the world. Several predictive and prognostic biomarkers for non-small cell lung …
Article scientifique
Role of miR-15b and miR-130b as Non-Invasive Biomarkers in Hepatocellular Carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancers, and the second cause of cancer-related deaths worldwide. …