440 publication(s) trouvée(s)
Article scientifique
Advances in Molecular Diagnostics and Targeted Therapeutic Approaches in HER-2 Positive Breast Cancer
Human epidermal growth factor receptor 2 (HER2) is linked with aggressive tumors in breast carcinoma patients and results in poor …
Article scientifique
Genetic Mutations in Senegalese Women with Breast Cancer
OBJECTIVE: This study aimed to understand the effect of nucleotide mutations and microsatellite locus instability on breast cancer in Senegalese …
Article scientifique
Investigations of Cu2ONPs - Orange Peels: Biosynthesis, Characterization, and Anticancer Activity on a Cytotoxic Breast Cancer Cell Line
BACKGROUND: The study aimed to evaluate the efficacy of nanocomposites extracted from orange peels in targeting and combating MCF-7 cells. …
Article scientifique
Decreased Expression Levels Of PIWIL2, PIWIL3 and PIWIL4 Are Associated with Poor Prognosis and Worse Survival in Bladder Cancer Patients
BACKGROUND: Bladder cancer (BC) remains one of the most prevalent and recurrent malignancies worldwide. Identification of early biomarkers and prognostic …
Article scientifique
Knowledge Attitude and Determinants of Cervical Cancer Screening Uptake Among Age-Eligible Women and Male Partners in Makurdi North-Central Nigeria
OBJECTIVE: To inform effective intervention strategies, this study aimed to assess the knowledge, attitude, and determinants of cervical cancer screening …
Article scientifique
First Screening For Germline Variations In Exon 5 PTEN Gene and Their Contribution to Triple Negative Breast Cancer in Eastern Algeria
OBJECTIVE: Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype associated with younger age, bigger tumor size, …
Article scientifique
Oral Contraceptives Use and Colorectal Cancer Risk Among Moroccan Women: A Case-Control Study
Objective: Colorectal cancer (CRC) encompasses both non-modifiable and modifiable risk factors. While diet remains the main factor influencing CRC risk, …
Article scientifique
Introduction of the HPV Vaccine among Young Girls to Reduce the Long-Term Risk of Cervical Cancer in Eswatini: Programmatic Decision and Roll Out
BACKGROUND: Cervical cancer is a significant public health concern in Eswatini. In June 2023, the Eswatini government launched a national …
Article scientifique
Effect of a Nurse-Led Educational Intervention on the Knowledge, Perceptions and Uptake of Cervical Cancer Screening among HIV-Infected Women in Kenya
BACKGROUND: Health education influences the sociocultural health beliefs and enhances the decision making of women resulting in a change in …
Article scientifique
The Effect of Surgeon Experience on the Recurrence of Non-Muscle Invasive Bladder Cancer (NMIBC), Following Transurethral Resection of the Bladder Tumor (TURBT): A double Blinded Prospective Randomized Study
BACKGROUND: Transurethral resection of the bladder tumor (TURBT) followed by intravesical instillation therapy is the standard treatment for non-muscle invasive …
Article scientifique
Phase II Study to Evaluate the Safety and Efficacy of Neoadjuvant Chemotherapy with Weekly Paclitaxel and Carboplatin Followed by Radical Chemoradiation in Locally Advanced Cervical Cancer in Egyptian Population
BACKGROUND: Since 1999, platinum based chemoradiation (CRT) is the standard treatment for locally advanced cervical cancer patients, but the estimated …
Article scientifique
The DNA Methylation is Involved in Liver Cancer Metastasis via Regulation of E- cadherin Gene
Over 90% of primary liver tumors are hepatocellular carcinomas (HCCs). In mammalian cells, chromatin remodeling and transcription regulation are significantly …
Article scientifique
The Predictive Significance of Galectin 3 Expression in Patients with Unresectable Non-Small Cell Lung Cancer without EGFR or ALK Mutations Treated Platinum-Based Doublet Chemotherapy
OBJECTIVE: The objective of our study is to evaluate the predictive value of cytoplasmic Galectin-3 (Gal-3) expression in tumor cells …
Article scientifique
Correlation between Isocitrate Dehydrogenase Mutation and Immunohistochemical Expression of DNA Mismatch Repair Proteins in the Prognosis of Gliomas
BACKGROUND: Gliomas comprise about a third of all brain tumors and 80% of malignant brain cancers. Isocitrate dehydrogenase (IDH) normally …
Article scientifique
Antioxidant and Apoptotic Activity of Curcumin Nanoparticles on HEp-2 Cell Line
INTRODUCTION: Nanocurcumin is a widely used anti-inflammatory agent due to its antioxidant and anti-inflammatory properties. AIM OF THE STUDY: The …
Article scientifique
Exposure of Spargue Dawley Rats to Phone Cell Electromagnetic Field Frequency and Related Physiological, Apoptotic and Molecular Profile of Para Oral Tissues: In–vivo Study
OBJECTIVE: Daily exposure to cellular EMF induced a long run deleterious impact. Accordingly, the aim of the present work is …
Article scientifique
Role of Lyn Immunohistochemical Staining in Progression of Colorectal Carcinoma
OBJECTIVE: To investigate the immunohistochemical expression of Lyn in colorectal adenocarcinoma with its corresponding lymph node metastasis and correlation with …
Article scientifique
The Fusion Genes and Their Relation with Genetic Variants in Egyptian AML Patients
BACKGROUND: Acute myeloid leukemia (AML) is a clonal malignant disorder of the bone marrow. Genetic aberrations have an unequivocal role …
Article scientifique
Long-Term Survival Rate for Moroccan Patients with Differentiated Thyroid Cancer
BACKGROUND: The prognosis for differentiated thyroid cancer of follicular origin (DTC) is generally good, with survival rates comparable to those …
Article scientifique
Behavioural and Social Drivers (BeSD) of HPV vaccination in Zimbabwe: A Rapid Scoping Review of Literature
BACKGROUND: Regardless of the World Health Organization's recommendation for human papillomavirus (HPV) vaccination, Zimbabwe still faces challenges in achieving optimal …