281 publication(s) trouvée(s)
Article scientifique
Treatment outcomes of esophageal cancer in Eastern Africa: protocol of a multi-center, prospective, observational, open cohort study
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a major cause of cancer morbidity and mortality in Eastern Africa. The majority …
Article scientifique
Survival impact of additional chemotherapy after adjuvant concurrent chemoradiation in patients with early cervical cancer who underwent radical hysterectomy
BACKGROUND: To determine whether additional chemotherapy after concurrent chemoradiation (CCRT) improves survival outcomes in patients with early cervical cancer who …
Article scientifique
Contemporary treatment patterns and survival of cervical cancer patients in Ethiopia
BACKGROUND: Cervical cancer is the second commonly diagnosed cancer and the second leading cause of cancer death in women in …
Article scientifique
Cognitive functioning and its associated factors among breast cancer patients on chemotherapy at Tikur Anbessa specialized hospital, Addis Ababa Ethiopia: an institution-based comparative cross-sectional study
BACKGROUND: Breast cancer is the second leading cause of cancer in the world. It is the commonest type of cancer …
Article scientifique
Validation of Mini-Mental Adjustment to Cancer scale in a Moroccan sample of breast cancer women
BACKGROUND: The Mini-Mental Adjustment to Cancer Scale (Mini-MAC) instrument is commonly used worldwide by professionals of oncology, but the scale …
Article scientifique
Cervical cancer screening “see and treat approach”: real-life uptake after invitation and associated factors at health facilities in Gondar, Northwest Ethiopia
BACKGROUND: Although cervical cancer is a preventable disease, screening coverage in Ethiopia is far below the target. There is limited …
Article scientifique
Barriers and facilitators in cervical cancer screening uptake in Abidjan, Côte d'Ivoire in 2018: a cross-sectional study
BACKGROUNDS: Cervical cancer (CC) incidence remains unacceptably high in Côte d'Ivoire. In an effort to prevent this malignant condition, a …
Article scientifique
Feasibility and first results of a prospective cohort study to investigate cisplatin-associated ototoxicity amongst cancer patients in South Africa
BACKGROUND: Cervical cancer, one of the most common cancers affecting females in South Africa, commonly requires a cisplatin-based-treatment regimen, which …
Article scientifique
Viral hepatitis associated hepatocellular carcinoma on the African continent, the past, present, and future: a systematic review
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in Africa. In Africa, the major causes …
Article scientifique
Evaluating essential medicines for treating childhood cancers: availability, price and affordability study in Ghana
INTRODUCTION: Access to childhood cancer medicines is a critical global health challenge. There is a lack of sufficient context-specific data …
Article scientifique
The evolution of the socio-cultural and religious characteristics of cancer patients in Morocco: case of the National Institute of Oncology Rabat
BACKGROUND: In 2020, Morocco recorded more than 59,370 new cases of cancer and more than 35,265 cases of death (International …
Article scientifique
Invasive breast Cancer treatment in Tanzania: landscape assessment to prepare for implementation of standardized treatment guidelines
BACKGROUND: Incidence of breast cancer continues to rise in low- and middle-income countries, with data from the East African country …
Article scientifique
DNA methylation signatures associated with prognosis of gastric cancer
BACKGROUND: Few studies have examined prognostic outcomes-associated molecular signatures other than overall survival (OS) for gastric cancer (GC). We aimed …
Article scientifique
Knock-down of LRP/LR influences signalling pathways in late-stage colorectal carcinoma cells
BACKGROUND: The 37 kDa/67 kDa laminin receptor (LRP/LR) is involved in several tumourigenic-promoting processes including cellular viability maintenance and apoptotic …
Article scientifique
Women’s experiences in a community-based screen-and-treat cervical cancer prevention program in rural Malawi: a qualitative study
BACKGROUND: Malawi has the world's highest cervical cancer incidence and mortality due to high rate of HIV coupled with inadequate …
Article scientifique
Prevalence of childhood Cancer among children attending referral hospitals of outpatient Department in Ethiopia
Abstract Introduction Childhood cancer is one of the leading causes of morbidity and mortality in the pediatrics age group. The …
Article scientifique
Knowledge towards cervical cancer screening and associated factors among urban health extension workers at Addis Ababa, Ethiopia: facility based cross-sectional survey
BACKGROUND: Cervical cancer is preventable and remains a leading cause of avoidable death among women in the world. In a …
Article scientifique
Following cytotoxic nanoconjugates from injection to halting the cell cycle machinery and its therapeutic implications in oral cancer
BACKGROUND: The concept of personalized therapy has been proven to be a promising approach. A popular technique is to utilize …
Article scientifique
Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer
BACKGROUND: Inhibition of nuclear import via Karyopherin beta 1 (Kpnβ1) shows potential as an anti-cancer approach. This study investigated the …
Article scientifique
Colorectal cancer incidence and mortality trends by sex and population group in South Africa: 2002–2014
BACKGROUND: South Africa (SA) has experienced a rapid transition in the Human Development Index (HDI) over the past decade, which …