281 publication(s) trouvée(s)
Article scientifique
Determinants of cervical cancer screening utilization among women attending health facilities of Dessie town, Northeast Ethiopia
INTRODUCTION: Despite the higher burden of cervical cases, screening programs in highly affected developing countries remained low. This made the …
Article scientifique
Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using Free Fibular Flap with and without CAD/CAM Customized Osteotomy Guide: A Randomized Controlled Clinical Trial
BACKGROUND: Reconstruction of mandibular defects following ablative surgery remains a challenge even for experienced surgeons. Virtual planning and guided surgery, …
Article scientifique
Obese mammary tumour-bearing mice are highly sensitive to doxorubicin-induced hepatotoxicity
BACKGROUND: Breast cancer is a major health burden for women, worldwide. Lifestyle-related risk factors, such as obesity and being overweight, …
Article scientifique
Prognostic markers in patients with chronic lymphocytic leukaemia on targeted therapy, chemoimmunotherapy with anti-CD20 monoclonal antibody: a systematic review and meta-analysis of prognostic factors
Abstract Combination chemoimmunotherapy (CIT) consisting of anti-CD20 has improved the progression-free survival (PFS) and overall survival (OS) of patients with …
Article scientifique
Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa
BACKGROUND: Our review discuss (i) the findings from analyzed data that have examined KRAS, NRAS and BRAF mutations in patients …
Article scientifique
Left-sided colorectal cancer distinct in indigenous African patients compared to other ethnic groups in South Africa
INTRODUCTION: A large proportion of indigenous African (IA) colorectal cancer (CRC) patients in South Africa are young (< 50 years), …
Article scientifique
Socio-demographic determinants of cervical cancer screening uptake among women of child-bearing age in Mangochi, Malawi: a facility-based cross-sectional study
BACKGROUND: Cervical cancer (CC) is the number one leading cause of death among women in Malawi. However, it is generally …
Article scientifique
Implication of extrinsic and intrinsic apoptotic pathways in the targeted therapy of hepatocellular carcinoma using aptamer-labeled viramidine nanoparticles
Abstract Hepatocellular carcinoma (HCC) is a global health problem with regional differences in epidemiological statistics. Co-assembling the drug nanoparticles and …
Article scientifique
Long-term follow-up on HIV infected and non-infected women with cervical cancer from Tanzania: staging, access to cancer-directed therapies and associated survival in a real-life remote setting
BACKGROUND: Worldwide 85% of cervical cancer (CC) related deaths occur in low- and middle-income countries. Sub-Saharan Africa is burdend by …
Article scientifique
High prevalence of and factors associated with human papillomavirus infection among women attending a tertiary hospital in Gauteng Province, South Africa
BACKGROUND: Persistent high-risk (hr) human papillomavirus (HPV) infection is a necessary cause of cervical cancer. Cervical cancer is a major …
Article scientifique
Quality of life and its influencing factors among breast cancer patients at Tikur Anbessa specialised hospital, Addis Ababa, Ethiopia
BACKGROUND: Quality of life (QoL) has become an important measure for evaluating cancer patients' treatment and prognosis. Breast cancer patients …
Article scientifique
The impact of a breast cancer educational intervention in Ghanaian high schools
INTRODUCTION: Globally breast cancer is the leading cause of cancer with an estimated 2.3 million new cases and 685,000 deaths …
Article scientifique
Evolution of patterns of care for women with cervical cancer in Morocco over a decade
BACKGROUND: We conducted a Pattern-of-care (POC) study at two premier-most public-funded oncology centers in Morocco to evaluate delays in care …
Article scientifique
A protocol to clinically evaluate liquid biopsies as a tool to speed up diagnosis of children and young adults with aggressive infection-related lymphoma in East Africa “(AI-REAL)”
BACKGROUND: The capacity for invasive tissue biopsies followed by histopathology diagnosis in sub-Saharan Africa is severely limited. Consequently, many cancer …
Erratum
Correction: Breast cancer screening in sub-Saharan Africa: a systematic review and ethical appraisal
Article scientifique
Baseline blood count levels increase odds of cytopenia among CML patients in Kenya: a case control study
Abstract Background Imatinib is the gold standard for the treatment of all phases of Philadelphia positive Chronic Myeloid Leukemia (CML). …
Article scientifique
A 10-year retrospective study of lung cancer in Uganda
BACKGROUND: Lung cancer is a leading cause of cancer-related deaths in Uganda. In this study, we aimed to describe the …
Article scientifique
Acceptability and safety of thermal ablation to prevent cervical cancer in sub-Saharan Africa
BACKGROUND: The World Health Organization recommends thermal ablation as an alternative to cryotherapy to treat women with precancerous lesions in …
Article scientifique
Prevalence of specific and recurrent/founder pathogenic variants in BRCA genes in breast and ovarian cancer in North Africa
BACKGROUND: Elucidation of specific and recurrent/founder pathogenic variants (PVs) in BRCA (BRCA1 and BRCA2) genes can make the genetic testing, …
Article scientifique
Breast cancer screening in sub-Saharan Africa: a systematic review and ethical appraisal
BACKGROUND: The aim of this systematic review was to evaluate the evidence and clinical outcomes of screening interventions and implementation …