281 publication(s) trouvée(s)
Article scientifique
3D-based strain analysis and cardiotoxicity detection in cancer patients received chemotherapy
BACKGROUND: Chemotherapy-induced cardiotoxicity has become a prevalent complication. Regular monitoring of patients who received chemotherapy using 3D strain parameters may …
Article scientifique
Characterization of a novel peptide mined from the Red Sea brine pools and modified to enhance its anticancer activity
Drug resistance is a major cause of the inefficacy of conventional cancer therapies, and often accompanied by severe side effects. …
Article scientifique
Treatment compliance among adult cervical cancer patients receiving care at Uganda cancer institute, Uganda: a retrospective data review
BACKGROUND: Cervical cancer is one of the most common cancers and a major cause of morbidity among women globally. Chemoradiation …
Article scientifique
Vaginal microbiome community state types and high-risk human papillomaviruses in cervical precancer and cancer in North-central Nigeria
BACKGROUND: High risk human papillomaviruses (HR-HPV) have a causal role in cervical oncogenesis, and HIV-mediated immune suppression allows HR-HPV to …
Article scientifique
Interferon-induced transmembrane protein 3 in hepatocellular carcinoma patients
OBJECTIVE: The study aimed to investigate the over expression of IFITM3 in hepatocellular carcinoma Egyptian patients. BACKGROUND: Hepatocellular carcinoma (HCC) …
Article scientifique
Hemoglobinopathies, merozoite surface protein-2 gene polymorphisms, and acquisition of Epstein Barr virus among infants in Western Kenya
Abstract Background Epstein Barr virus (EBV)-associated endemic Burkitt’s Lymphoma pediatric cancer is associated with morbidity and mortality among children resident …
Article scientifique
Mediators and moderators of the effect of the game changers for cervical cancer prevention intervention on cervical cancer screening among previously unscreened social network members in Uganda
INTRODUCTION: Cervical cancer (CC) rates are high in Uganda, yet CC screening rates are very low. Our peer advocacy group …
Article scientifique
Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma
BACKGROUND: There is considerable evidence that microRNAs (miRNAs) regulate several key tumor-associated genes/pathways and may themselves have a dual regulatory …
Article scientifique
Experiences of patients on cancer treatment regarding decentralization of oncology services at a tertiary hospital in the Eastern Cape
BACKGROUND: The cancer burden is a global public health concern associated with high morbidities and mortalities. Low and middle-income countries …
Article scientifique
Cervical cancer screening utilization and its predictors among women in bench Sheko Zone, Southwest Ethiopia: using health belief model
BACKGROUND: Cervical cancer is the fourth most frequently diagnosed and found to be the leading cause of cancer death in …
Article scientifique
Delay in diagnosis and associated factors among children with cancer admitted at pediatric oncology ward, University of Gondar comprehensive specialized hospital, Ethiopia: a retrospective cross-sectional study
BACKGROUND: Delay in the diagnosis of childhood cancer is one of the major health problem that contribute to decreased survival …
Article scientifique
Prevalence, trends and distribution of lifestyle cancer risk factors in Uganda: a 20-year systematic review
BACKGROUND: Cancer is becoming an important public health problem in Uganda. Cancer control requires surveillance of lifestyle risk factors to …
Article scientifique
HOXA9 gene promotor methylation and copy number variation of SOX2 and HV2 genes in cell free DNA: A potential diagnostic panel for non-small cell lung cancer
BACKGROUND: Most cases of lung cancer are diagnosed at advanced stage. Detection of genetic and epigenetic markers in cell-free DNA …
Article scientifique
Increased prevalence of the founder BRCA1 c.5309G>T and recurrent BRCA2 c.1310_1313delAAGA mutations in breast cancer families from Northerstern region of Morocco: evidence of geographical specificity and high relevance for genetic counseling
BACKGROUND: Inherited mutations in the breast cancer susceptibility genes BRCA1 and BRCA2 (BRCA1/2) confer high risks of breast and ovarian …
Article scientifique
One year overall survival of wilms tumor cases and its predictors, among children diagnosed at a teaching hospital in South Western Uganda: a retrospective cohort study
BACKGROUND: Wilms tumor (WT) is the second most common solid tumor in Africa with both low overall survival (OS) and …
Article scientifique
Biochemical and pathophysiological improvements in rats with thioacetamide induced-hepatocellular carcinoma using aspirin plus vitamin C
Abstract Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death, so we should be concerned and …
Article scientifique
Factors associated with the uptake of clinical breast examination among women of reproductive age in Lesotho: analysis of a national survey
BACKGROUND: In low-resource settings with weak health systems, the WHO recommends clinical breast examination (CBE) as the most cost-effective breast …
Article scientifique
A cervical cancer biorepository for pharmacogenomics research in Zimbabwe
BACKGROUND: Research infrastructures such as biorepositories are essential to facilitate genomics and its growing applications in health research and translational …
Article scientifique
Frequency, severity, and factors associated with clinically significant drug-drug interactions among patients with cancer attending Mbarara Regional Referral Hospital Cancer Unit, Uganda
BACKGROUND: Cancer is a major public health problem with pharmacotherapy being the cornerstone of its management. Cancer patients receive multiple …
Article scientifique
Prostate cancers in men under the age of 50: about a series in Togo, Sub-Saharan Africa
BACKGROUND: Prostate cancer is a public health problem and increasingly diagnosed in men under 50 years of age. This cancer …