391 publication(s) trouvée(s)
Article scientifique
Eco-friendly monitoring of triclosan as an emerging antimicrobial environmental contaminant utilizing electrochemical sensors modified with CNTs nanocomposite transducer layer
Abstract Environmental appearance of antimicrobials due to frequent use of personal care products as recommended by WHO can cause serious …
Article scientifique
Green chromatographic methods for determination of co-formulated lidocaine hydrochloride and miconazole nitrate along with an endocrine disruptor preservative and potential impurity
Recently, green analytical chemistry (GAC) is a key issue towards the idea of sustainability, the analytical community is focused on …
Article scientifique
Homogeneous liquid–liquid microextraction coupled with HPLC/DAD for determination of nirmatrelvir and ritonavir as COVID-19 combination therapy in human plasma
. The method employed sugaring-out induced homogeneous liquid-liquid microextraction to improve sensitivity. Optimization of the method was performed using the …
Article scientifique
Simultaneous analysis of the of levamisole with triclabendazole in pharmaceuticals through developing TLC and HPLC–PDA chromatographic techniques and their greenness assessment using GAPI and AGREE methods
Two simple and rapid chromatographic methods were developed and validated for the analysis of levamisole and triclabendazole simultaneously in pure …
Article scientifique
An innovative combination of Box-Behnken design and ecofriendly approaches for the simultaneous determination of aspirin, clopidogrel, atorvastatin and rosuvastatin in their fixed-dose combination tablets
Abstract Three-levels Box-Behnken design was used in the experimental design approach for the optimization of chromatographic parameters to achieve the …
Article scientifique
Synthesis, characterization, DNA binding interactions, DFT calculations, and Covid-19 molecular docking of novel bioactive copper(I) complexes developed via unexpected reduction of azo-hydrazo ligands
Abstract In this work, we focused on the 3rd goal of the sustainable development plan: achieving good health and supporting …
Article scientifique
Facile solvent-free modified biochar for removal of mixed steroid hormones and heavy metals: isotherm and kinetic studies
Abstract Water contamination has become a global challenge to human survival. Non-biodegradable heavy metal cations and steroid hormones could accumulate …
Article scientifique
Impact of carbonization conditions and adsorbate nature on the performance of activated carbon in water treatment
Abstract The physical and chemical structure of activated carbon (AC) varies with the carbonization temperature, activation process and time. The …
Article scientifique
Greenness assessment of two chromatographic methods developed for the determination of Mupirocin in two binary mixtures along with its impurity
Abstract Two simple, accurate and precise chromatographic methods have been developed and validated for estimating Mupirocin (MUP) in two binary …
Article scientifique
Continuous wavelet transform for solving the problem of minor components in quantitation of pharmaceuticals: a case study on the mixture of ibuprofen and phenylephrine with its degradation products
The presence of minor components represents a challenging problem in spectrophotometric analysis of pharmaceuticals. If one component has a low …
Article scientifique
Different methods for resolving overlapping UV spectra of combination medicinal dose forms of ciprofloxacin and metronidazole
Four simple, specific, easy, precise and accurate spectrophotometric methods were developed for the first time to examine ciprofloxacin and metronidazole …
Article scientifique
Development, validation and greenness assessment of a new electro-driven separation method for simultaneous analysis of cefixime trihydrate and linezolid in their fixed dose combination
The establishment and validation of a straightforward, accurate, and eco-friendly capillary zone electrophoretic-diode array detection (CZE-DAD) procedure has been presented …
Article scientifique
Green wastewater treatment of repurposed COVID-19 therapy (levofloxacin) using synthesized magnetite pectin nanoparticles, comparison with mesoporous silica nanoparticles
RATIONALE: Antibiotics have been detected worldwide in the aquatic environment. Moreover, certain classes of antibiotics have been repurposed for the …
Article scientifique
Synthesis of inventive biphenyl and azabiphenyl derivatives as potential insecticidal agents against the cotton leafworm, Spodoptera littoralis
Abstract The emergence of pest resistance of Spodoptera littoralis (order; Lepidoptera, family; Noctuidae) towards the large scale of different classes …
Article scientifique
Smart chemometrics-assisted spectrophotometric methods for efficient resolution and simultaneous determination of paracetamol, caffeine, drotaverine HCl along with three of their corresponding related impurities
Three novel, simple and accurate multivariate spectrophotometric assisted mathematical techniques were developed for determination of paracetamol, caffeine, drotaverine HCl and …
Article scientifique
Development of an eco-friendly HPLC method for the stability indicating assay of binary mixture of ibuprofen and phenylephrine
The development and validation of the stability indicating HPLC technique has contributed to the understanding of the stability profile of …
Article scientifique
Green synthesis of highly functionalized heterocyclic bearing pyrazole moiety for cancer-targeted chemo/radioisotope therapy
Abstract New derivatives of heterocyclic bearing pyrazole moiety were synthesized (eight new compounds from 2 to 9) via green synthesis …
Article scientifique
Fragment merging approach for design, synthesis, and biological assessment of urea/acetyl hydrazide clubbed thienopyrimidine derivatives as GSK-3β inhibitors
Abstract New thienopyrimidine derivatives were designed and synthesized as GSK-3β inhibitors based on the structure of active binding site of …
Article scientifique
Comparative HPTLC study for simultaneous determination of ivabradine and metoprolol using UV and fluorescence detectors
Abstract New, simple, accurate, sensitive and validated high performance thin layer chromatographic (HPTLC) method coupled with UV absorbance mode and …
Article scientifique
Higher sensitive selective spectrofluorometric determination of ritonavir in the presence of nirmatrelvir: application to new FDA approved co-packaged COVID-19 pharmaceutical dosage and spiked human plasma
BACKGROUND: Ritonavir was recently combined with nirmatrelvir in a new approved co-packaged medication form for the treatment of COVID-19. Quantitative …