391 publication(s) trouvée(s)
Article scientifique
Preparation of hydroxyethyl cellulose/ mangiferin edible films and their antimicrobial properties
In this study, we have used hydroxyethyl cellulose (HEC) to prepare antimicrobial films for multipurpose applications. Using HEC gives mangiferin …
Article scientifique
Synthesis, spectral characterization, and theoretical investigation of the photovoltaic properties of (E)-6-(4-(dimethylamino)phenyl)diazenyl)-2-octyl-benzoisoquinoline-1, 3-dione
Abstract This research work focuses on the synthesis, characterization through spectra (FT-IR, UV–vis, and 1H-NMR) investigations, and the use of …
Article scientifique
Synthesis, antimalarial, antileishmanial evaluation, and molecular docking study of some 3-aryl-2-styryl substituted-4(3H)-quinazolinone derivatives
Abstract Quinazolinones are a diverse group of nitrogen-containing heterocyclic compounds with promising antimalarial and antileishmanial activities. Herein, some 3-aryl-2-styryl substituted-4(3 …
Article scientifique
Application of Box-Behnken experimental design and response surface methodology for selecting the optimum RP-HPLC conditions for the simultaneous determination of methocarbamol, indomethacin and betamethasone in their pharmaceutical dosage form
Abstract An isocratic RP-HPLC method has been developed for the separation and determination of methocarbamol (MTL), indomethacin (IND), and betamethasone …
Article scientifique
Hydrophilic gold nanospheres: influence of alendronate, memantine, and tobramycin on morphostructural features
Turkevich gold nanospheres are the original nanospheres that have been modified over time. Its combination with targeting medications such as …
Article scientifique
Screen-printed sensors for efficient potentiometric analysis of tolperisone hydrochloride in presence of its co-formulated drugs
Abstract Researchers seeking for green chemistry to help safeguard and boost the economy and the environment by discovering unique ways …
Article scientifique
Development and validation of a novel Spectrofluorimetric method of oral anticoagulant Edoxaban via derivatization with 9-fluorenyl methyl chloroformate: green assessment of the method by Eco-Scale and ComplexGAPI
A precise, sensitive eco-friendly, simple, rapid, and derivative spectrofluorimetric method was developed to quantify edoxaban tosylate monohydrate in pure form …
Article scientifique
QSRR modeling of the chromatographic retention behavior of some quinolone and sulfonamide antibacterial agents using firefly algorithm coupled to support vector machine
Quinolone and sulfonamide are two classes of antibacterial agents with an opulent history of medicinal chemistry features that contribute to …
Article scientifique
Effect of sulfur doping of zinc-imidazole coordination polymer (ZnIm CP) as a novel photocatalyst for degradation of ionic dyes
Abstract Zinc-Imidazole coordination polymer (ZnImCP) was simply synthesized hydrothermally at relatively low temperature (70 °C) from zinc acetate and imidazole. …
Article scientifique
Synthesis, biological evaluation and molecular docking of new triphenylamine-linked pyridine, thiazole and pyrazole analogues as anticancer agents
Abstract A new series of pyridine, thiazole, and pyrazole analogues were synthesized. The pyridone analogues 4a-e were synthesized by treating …
Article scientifique
Synthesis, characterization, and cytotoxicity of doxorubicin-loaded polycaprolactone nanocapsules as controlled anti-hepatocellular carcinoma drug release system
BACKGROUND: Free doxorubicin (Dox) is used as a chemotherapeutic agent against hepatocellular carcinoma (HCC), but it results in cardiotoxicty as …
Article scientifique
Spectroscopic details on the molecular structure of pyrimidine‑2‑thiones heterocyclic compounds: computational and antiviral activity against the main protease enzyme of SARS-CoV-2
Computational tools in investigating of spectral heterocyclic compounds ranges based on pyrimidine‑2‑thiones, take some importance in identifying their molecular and …
Article scientifique
Assessment of selected heavy metals in honey samples using flame atomic absorption spectroscopy (FAAS), Ethiopia
Abstract Honey is a natural, sugary and sticky liquid that is produced from the nectars of flowers by the bees. …
Article scientifique
Enhanced cytotoxic effect of doxorubicin conjugated gold nanoparticles on breast cancer model
BACKGROUND: The difficulty of achieving targeted drug delivery following administration of presently marketed anticancer therapeutics is still a concern. Metallic …
Article scientifique
Gold nanoparticles loaded chitosan encapsulate 6-mercaptopurine as a novel nanocomposite for chemo-photothermal therapy on breast cancer
Abstract Background As a promising strategy to overcome the therapeutic disadvantages of 6-mercaptopurine (6MP), we proposed the encapsulation of 6MP …
Article scientifique
Nitrogen and sulfur-doped carbon quantum dots as fluorescent nanoprobes for spectrofluorimetric determination of olanzapine and diazepam in biological fluids and dosage forms: application to content uniformity testing
A validated, sensitive, and simple spectrofluorimetric method was developed for the analysis of two important CNS-acting drugs, olanzapine and diazepam, …
Article scientifique
Eco-friendly resolution of spectrally overlapping signals of a combined triple-action over-the-counter pharmaceutical formulation for symptomatic management of COVID-19 pandemic: application to content uniformity testing
Abstract Currently, all researchers are concentrating their efforts on countering the COVID-19 pandemic. The majority of patients are managed at …
Article scientifique
Smart stability indicating spectrophotometric methods for determination of modafinil: the promising treatment for post-covid neurological syndrome
Abstract Modafinil (MDF) is one of the neurostimulants with a potential effect in the COVID-19 ICU ventilated patients and post-COVID …
Article scientifique
Experimentally designed electrochemical sensor for therapeutic drug monitoring of Ondansetron co-administered with chemotherapeutic drugs
Abstract The experimental design extracts valuable information about the main effects and interactions from the least number of experiments. The …
Article scientifique
Stimulated generation of photobiogas by morphologically tuned nanostructured ZnO and ZnO/TiO2
Abstract The photocatalytic degradation (PCD) of ethanol in an inert atmosphere on catalysis was explored in a lab-scale experiment. A …