391 publication(s) trouvée(s)
Article scientifique
Synthesis and biological evaluation of [131I]iodocarvedilol as a potential radiopharmaceutical for heart imaging
Abstract The optimization of the radiolabeling yield of carvedilol with iodine-131 was described. Dependence of the labeling yield of [131I]iodocarvedilol …
Article scientifique
An eco-friendly separation-based framework for quantitative determination and purity testing of an antihypertensive ternary pharmaceutical formulation
Abstract Designing new, verified methodologies with a focus on sustainability, analytical efficiency, simplicity, and the environment has become a major …
Article scientifique
Use of green fluorescent nano-sensors for the determination of furosemide in biological samples and pharmaceutical preparations
BACKGROUND: Carbon quantum dots (CQDs) are new class of carbon nanoparticles. Recently, they have been widely used as fluorescent probes …
Article scientifique
The simultaneous measurement of quaternary mixture in over-the-counter cold medications using sequential spectrophotometric resolution approach enhanced with in-lab sample enrichment
Abstract A sequential spectrophotometric resolution technique (SSRT) was developed in this study without the use of systematic separation procedures to …
Article scientifique
Determination of Clomipramine using eco-friendly solid-contact ionophore-doped potentiometric sensor
INTRODUCTION: ) is 13-310 ng/mL, the therapeutic range is 220-500 ng/mL and its toxic effect appears in doses above 900 …
Article scientifique
Insights of different analytical approaches for estimation of budesonide as COVID-19 replication inhibitor in its novel combinations: green assessment with AGREE and GAPI approaches
Abstract Simple, direct, rapid, and sensitive HPLC and spectrophotometric methods were established for simultaneous estimation of a novel combination of …
Article scientifique
HPLC-DAD technique for the quantification of a recently approved anti-diabetic triple combination along with two toxic official impurities: Toxicity confirmation aided by molecular docking application
Abstract Background Gliflozins and gliptins are two distinct groups of pharmacological drugs that reduce blood glucose levels in individuals with …
Article scientifique
Enantioseparation, quantification, molecular docking and molecular dynamics study of five β-adrenergic blockers on Lux-Cellulose-2 column
Enantioseparation of five β-adrenergic blockers was studied using two mobile phases on a cellulose tris(3-chloro-4-methylphenylcarbamate) (Lux-Cellulose-2) chiral column in normal …
Article scientifique
Three developed spectrophotometric methods for determination of a mixture of ofloxacin and ornidazole; application of greenness assessment tools
This work is dedicated to the greenness estimation of three proposed spectrophotometric techniques [e.g., ratio difference (RD), mean centering of …
Article scientifique
Micellar eco-friendly HPLC method for simultaneous analysis of ternary combination of aspirin, atorvastatin and ramipril: application to content uniformity testing
BACKGROUND: Cardiovascular disease medications such as aspirin (ASP), statins like atorvastatin (ATR), and blood pressure-lowering drugs including ACE inhibitors like …
Article scientifique
Green adherent degradation kinetics study of Nirmatrelvir, an oral anti-COVID-19: characterization of degradation products using LC–MS with insilico toxicity profile
Abstract The SARS-CoV-2 virus sets up a global catastrophe, and countries all around the world made significant efforts to halt …
Article scientifique
Earth-friendly-assessed silver-nanoparticles spectrophotometric method for rapid and sensitive analysis of Molnupiravir, an FDA-approved candidate for COVID-19: application on pharmaceutical formulation and dissolution test
Molnupiravir is the first oral direct-acting antiviral prodrug recently approved for the COVID-19 pandemic. Here and for the first time, …
Article scientifique
Synthesis, DFT investigations, antioxidant, antibacterial activity and SAR-study of novel thiophene-2-carboxamide derivatives
Abstract Synthetic strategy for the synthesis of thiophene 2-carboxamide derivatives substituted with hydroxyl, methyl and amino groups at position-3 was …
Article scientifique
Ultrastructural changes in the fat body of desert locust, Schistocerca gregaria (Orthoptera: Acrididae) treated with zinc chromium oxide nanostructures via chemical co-precipitation approach
The present work aims to investigate the ultrastructural changes in the fat body of fifth instar nymphs Schistocerca gregaria (Orthoptera: …
Article scientifique
Leidenfrost green synthesis method for MoO3 and WO3 nanorods preparation: characterization and methylene blue adsorption ability
Abstract Environmental pollution is a critical issue due to its impact on humans and other organisms. An important demand nowadays …
Article scientifique
Optimization of Cr (VI) removal from aqueous solution with activated carbon derived from Eichhornia crassipes under response surface methodology
Abstract Tannery industries’ effluent contains a high concentration of Cr (VI) which has the potential to affect the environment and …
Article scientifique
Biodegradable functionalized magnetite nanoparticles as binary-targeting carrier for breast carcinoma
In this study, Superparamagnetic magnetite nanoparticles (SPMNPs) are used in a new way as direct nanocarrier for Doxorubicin hydrochloride (DOX) …
Article scientifique
Comparative study of extension area based methods for spectrophotometric determination of desmopressin acetate in the presence of its acid-induced degradation products
Desmopressin acetate (DPA) is a synthetic analogue of vasopressin used in the treatment of diabetes insipidus, bedwetting, hemophilia A, and …
Article scientifique
Phytochemical investigation of Ludwigia adscendens subsp. diffusa aerial parts in context of its biological activity
Abstract Ludwigia adscendens subsp. diffusa (Onagraceae), an important aquatic herb widely distributed in the Nile River and canals in Egypt. …
Article scientifique
Validated HPLC–PDA methodology utilized for simultaneous determination of Etoricoxib and Paracetamol in the presence of Paracetamol toxic impurities
Etoricoxib (ETO), Paracetamol (PCM), and two toxic impurities for Paracetamol impurity K (4-aminophenol (PAP)) and impurity E (para-hydroxy acetophenone (PHA)) …