269 publication(s) trouvée(s)
Article scientifique
Chemical investigation and anti-trichinellosis activity of some ficus species leaves: in silico supported in vitro study
BACKGROUND: Worldwide, trichinellosis is a zoonotic illness. Albendazole (ALB), the nowadays anti-trichinellosis drug, has side effects and insufficient effectiveness. Ficus …
Article scientifique
Eucalyptus camaldulensis leaf extract enhances thalidomide efficacy in acute myeloid leukemia cells through modulation of mitochondrial energetics
BACKGROUND: Acute myeloid leukemia (AML) is an aggressive hematological malignancy characterized by high relapse rates and poor prognosis. Leukemic stem …
Article scientifique
Synergistic anti-cancer activity of Artemisia vulgaris L. aqueous extract with cisplatin against A549 lung cancer cell line
BACKGROUND: The increasing resistance and adverse effects associated with conventional chemotherapeutic agents such as cisplatin have prompted the investigation of …
Article scientifique
Manuka honey as a multifunctional therapeutic against Helicobacter pylori: from chemical profiling to in vitro potency and in vivo gastroprotective efficacy
Manuka honey contains bioactive phenolic and flavonoid chemicals with antibacterial and anti-inflammatory effects. The chemical profile and therapeutic efficiency of …
Article scientifique
Low-energy spontaneous fabrication of quercetin-loaded orange oil nanoemulsion for induction of colorectal cancer cell apoptosis
BACKGROUND: Phytochemicals showed potential application as anticancer agents. In the current investigation, quercetin, cold-pressed orange peel oil, and their mixture …
Article scientifique
Impact of extraction method on the chemical composition and antibacterial potential of Salvia fruticosa essential oil
BACKGROUND: Salvia fruticosa (Lamiaceae) is traditionally used to treat gastrointestinal (GIT) issues, stomach and abdominal pain, and ulcers. In this …
Article scientifique
Assessing the knowledge, attitude, and practice of Egyptian pharmacists on probiotics: a cross-sectional study
BACKGROUND: Probiotics, live microorganisms offering health benefits, have gained attention for their potential in preventing various health conditions. Despite their …
Article scientifique
Unveiling the wound-healing potential of Pisum sativum aerial biomass through integrated bioassay-guided, LC–MS/MS, and network pharmacology approaches
BACKGROUND: While Pisum sativum L. is primarily valued for its seeds, its aerial parts have received limited attention. This study …
Article scientifique
Considerations for sociocultural adaptations of a mindfulness-based program within a low socioeconomic setting in Cape Town, South Africa
BACKGROUND: The effectiveness of mindfulness-based programs in cultivating a sense of well-being has been demonstrated in many populations globally. However, …
Article scientifique
Revealing the anticancer potential of nano-encapsulated graviola extract on tongue carcinoma (SCC154) cell line: targeting the PI3K/AKT/mTOR pathway (in vitro study)
BACKGROUND: Graviola emerged as a promising anticancer agent, with nanotechnology enhancing drugs' therapeutic potential. The purpose of this work was …
Article scientifique
Phytochemical investigation, in vitro antioxidant, antibacterial activities of the leaf and fruit extracts of Hypericum revolutum Vahl (Amija), and essential oil composition of the leaf extract
Abstract Hypericum revolutum Vahl, a flowering plant in the Hypericaceae family, is traditionally used in Ethiopia to treat febrile illnesses …
Article scientifique
Chemical profiling and multidirectional biological effects of the aerial parts of two wild Commicarpus species; C. grandiflorus and C. plumbagineus
Abstract Background Commicarpus grandiflorus (A.Rich.) Standl. (CG), and Commicarpus plumbagineus (Cav.) Standl. (CP) (Nyctaginaceae family) have long been utilized in …
Article scientifique
Neuroprotective role of rice bran extract and its constituents in a neuroinflammatory mouse model
BACKGROUND: Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor known to play a critical role in regulating neuroinflammation and …
Erratum
Correction: Antimicrobial activity of Salvia spinosa against Enterococcus faecalis causing endodontic infections: an in-vitro, ex-vivo, and in-silico study
Article scientifique
Evaluation of prophylactic and therapeutic activity of camel whey protein and its trypsinized hydrolysate against experimental trichinellosis
BACKGROUND: To date, control of trichinellosis has been dependent on the conventional chemotherapeutic agent, albendazole (ALB), with its hitherto unsolved …
Article scientifique
Cicer arietinum extract as antitumor and protective agent against Ehrlich Solid Carcinoma-bearing mice
BACKGROUND: Cancer remains a significant global health challenge. Several plant-derived compounds have garnered the attention of cancer research for their …
Article scientifique
Chitosan nanocarriers loaded with Egyptian Calligonum comosum L'Hér. Extract: an eco-friendly approach for investigating triple-action biological activities
BACKGROUND: Calligonum comosum L'Hér. is a large perennial shrub that grows in the desert. This plant inhabits much of the …
Article scientifique
Marine actinobacterium Streptomyces vinaceusdrappus mediated nano-selenium: biosynthesis and biomedical activities
BACKGROUND: Biogenic Selenium nanoparticles (Se-NPs) have been receiving more attention, primarily due to their remarkable biomedical potential. This study was …
Article scientifique
Mapping evidence of spinal manipulation therapy for headaches in South Africa: a scoping review of grey literature
OBJECTIVE: Spinal manipulative therapy (SMT) has been demonstrated to be an effective management approach for primary headaches; however, current literature …
Article scientifique
Minneola tangelo essential oil exhibits antibacterial activity against multidrug-resistant pathogens while maintaining cell safety
Abstract Background The significant rise in antibiotic resistance has become an alarming situation urging the search for new antibacterial agents. …
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