269 publication(s) trouvée(s)
Article scientifique
Sub-chronic toxicity of the aqueous leaf extract of Ocimum lamiifolium Hochst. ex Benth on biochemical parameters and histopathology of liver and kidney in rats: in vivo and in- silico toxicity studies
BACKGROUND: The aerial part of Ocimum lamiifolium is commonly used in Ethiopian traditional medicine. Although this plant is mostly used …
Article scientifique
Antimicrobial analysis of honey against Staphylococcus aureus isolates from wound, ADMET properties of its bioactive compounds and in-silico evaluation against dihydropteroate synthase
BACKGROUND: One of the main challenges of wound healing is infection with multi-drug resistant (MDR) bacteria such as Staphylococcus aureus. …
Article scientifique
Cytotoxicity of the methanol extracts and compounds of Brucea antidysenterica (Simaroubaceae) towards multifactorial drug-resistant human cancer cell lines
Abstract Background Cancer remains a global health concern and constitutes an important barrier to increasing life expectancy. Malignant cells rapidly …
Article scientifique
Frequency, types, and factors associated with complementary and alternative medicine use among patients on maintenance haemodialysis
BACKGROUND: Despite progress in haemodialysis and conventional medicine approaches, many patients still struggle to maintain an acceptable quality of life …
Article scientifique
Anti-glycation, antiplatelet and antioxidant effects of different pomegranate parts
Abstract Background Platelet aggregation and advanced glycation end products (AGEs) and oxidative stress are known as key factors for the …
Article scientifique
Quercetin ameliorates acute lung injury in a rat model of hepatopulmonary syndrome
Abstract Background Common bile duct ligation (BDL) is a rat experimental model to induce biliary cirrhosis. Lung fibrosis and pulmonary …
Article scientifique
Anti-atherogenic and cardio-protective properties of sweet melon (Cucumis melo. L. Inodorus) seed extract on high fat diet induced obesity in male wistar rats
BACKGROUND: Cucumis melon is a medicinal plant with multiple pharmacological properties such as anti-inflammatory, antioxidant, and diuretic effects. An increasing …
Article scientifique
Mitigative effect of caffeine against diclofenac-induced hepato-renal damage and chromosomal aberrations in male albino rats
BACKGROUND: Among the most commonly consumed non-steroidal anti-inflammatory drugs (NSAID) is Diclofenac (Dic), especially in low-income countries due to its …
Éditorial
Editorial expression of concern: Retama monosperma n-hexane extract induces cell cycle arrest and extrinsic pathway-dependent apoptosis in jurkat cells
Article scientifique
RETRACTED ARTICLE: Polyphenols from Conyza dioscoridis (L.) ameliorate Alzheimer’s disease- like alterations through multi-targeting activities in two animal models
BACKGROUND: Recent investigations suggested that anticancer agents may inhibit the progression of Alzheimer's disease (AD) pathology. Conyza dioscoridis (L.) was …
Erratum
Correction: Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats
Article scientifique
Screening and evaluation of cytotoxicity and antiviral effects of secondary metabolites from water extracts of Bersama abyssinica against SARS-CoV-2 Delta
BACKGROUND: Bersama abyssinica is a common herb in Africa, with diverse medical uses in different areas. The plant is well-known …
Article scientifique
Bioprospecting of endophytic actinobacterium associated with Aloe ferox mill for antibacterial activity
BACKGROUND: The emergence of drug resistance among pathogens has resulted in renewed interest in bioprospecting for natural microbial products. METHODS: …
Article scientifique
Comparative evaluation of propolis nanostructured lipid carriers and its crude extract for antioxidants, antimicrobial activity, and skin regeneration potential
BACKGROUND: Propolis extracted from beehives has been conferred with natural antimicrobial and antioxidant properties. Hence, it has been recommended as …
Article scientifique
Herbal Medicine (HM) among pharmacy professionals working in drug retail outlets in Asmara, Eritrea: knowledge, attitude and prevalence of use
BACKGROUND: Globally, the usage of herbal medicines (HMs) is increasingly growing in treating and preventing various ailments. Although, HMs play …
Article scientifique
Antimalarial activity of solvent fractions of a leaf of Eucalyptus globulus labill against Plasmodium berghei infected mice
INTRODUCTION: The leaf of Eucalyptus globulus is commonly used in the traditional management of malaria. However, the efficacy of solvent …
Article scientifique
Phytochemical profile and antimicrobial activity of the leaves and stem bark of Symphonia globulifera L.f. and Allophylus abyssinicus (Hochst.) Radlk
INTRODUCTION: Symphonia globulifera and Allophylus abyssinicus are used in the management of skin rashes and sores, cough, malaria, digestive diseases, …
Article scientifique
In-vitro determination of antimicrobial activities of Eruca sativa seed oil against antibiotic-resistant gram-negative clinical isolates from neonates: a future prospect
Abstract Background The aim of this study is investigate the antimicrobial effect of plant oils against bacterial strains isolated from …
Article scientifique
Antimicrobial Evaluation of Sequentially extracted Leaf of Vernonia auriculifera Hiern (Rejicho)
BACKGROUND: Though there are reports about V. auriculifera antimicrobial activity, there is not enough information about its activity on some …
Article scientifique
Verification of the folkloric and anecdotal antidiabetic effects of Hypoxis hemerocallidea (Fisch., C.A. Mey. & Avé-Lall) and isolated, β-sitosterol using early-stage type II spontaneous diabetic mutant BKS-Leprdb mice
BACKGROUND: Previous studies in our laboratory in ex vivo assays have demonstrated H. hemerocallidea extract as potential antidiabetic agent through …