349 publication(s) trouvée(s)
Article scientifique
Streptomyces zaomycetitus strain GH90: a source of violet pigment with metabolic profiling and potential application in textile: in vitro supported by in silico studies and molecular docking
Dyes are used daily in the culinary, textile, paper, leather, and agricultural sectors. Synthetic colors pollute the environment and have …
Article scientifique
Prevalence of multi-drug resistant and extended-spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae among meat products sold at Sohag Governorate, Egypt
Abstract Meat products (MPs) are among the most commonly consumed food items in Egypt, and may serve as a potential …
Article scientifique
Assessment of MgO, ZnO, chitosan hydroxyapatite and silver hydroxyapatite nanoparticles against carbapenem-resistant Gram-negative Egyptian clinical isolates: a combined in-silico and in-vitro study
BACKGROUND: Currently, antimicrobial resistance (AMR) is one of the major global threats to public health; therefore, treating infectious diseases becamemore …
Article scientifique
Functional and genomic evaluation of novel exopolysaccharide produced by marine Pediococcus pentosaceus E3 with antidiabetic, anticancer, and anti-inflammatory potentials
Abstract Lactic acid bacteria (LAB) exopolysaccharides (EPS) are highly valuable due to their unique structure and functional properties. Pediococcus pentosaceus …
Article scientifique
Quorum quenching by endophytic Bacillus cereus AL1: a lactonase-based anti-virulence strategy against Pseudomonas aeruginosa
BACKGROUND: Pseudomonas aeruginosa infections are often challenging to treat due to multiple drug resistance, besides the development of biofilms and …
Article scientifique
Computational guided identification of novel anti-mycobacterial agent proved by in-vitro and in-vivo validation
Abstract Background An upsurge of antibiotic resistant bacteria such as Mycobacterium tuberculosis is recorded on daily bases as a result …
Article scientifique
Epigenetic modulation of Ceratorhiza hydrophila by 5-azacytidine enhances antifungal metabolite production: insights from antimicrobial, metabolic, genomic and computational analyses
BACKGROUND: The emergence of drug-resistant pathogens has stimulated the need for the development of new antimicrobial agents. Epigenetic modulation by …
Article scientifique
Presence of virulent Edwardsiella tarda in farmed nile tilapia and striped catfish
Abstract The production of striped catfish (Pangasianodon hypothalamus) has increased worldwide; recently, it was farmed with Nile tilapia in polyculture …
Article scientifique
In vitro and in vivo investigation of the antibacterial, antivirulence, and antiquorum sensing activities of β-carotene against difficult-to-treat resistant Pseudomonas aeruginosa
BACKGROUND: Difficult-to-treat resistant (DTR) Pseudomonas aeruginosa has strong drug resistance and can tolerate a diversity of antibiotics. Infections triggered by …
Article scientifique
Bacillus cereus-derived α-amylase disrupts biofilm formation and quorum sensing in multidrug-resistant Klebsiella pneumoniae
BACKGROUND AND OBJECTIVES: Klebsiella pneumoniae is a multidrug-resistant pathogen implicated in severe community- and hospital-acquired infections such as bacteremia, urinary …
Article scientifique
An insight into pyocyanin: production, characterization, and evaluation of its in vitro antibacterial, antifungal, antibiofilm and in vivo anti-schistosomal potency
BACKGROUND: Tackling the high demand for alternative therapeutic options, especially for multi-drug-resistant organisms, has awakened interest in naturally originated biomolecules …
Article scientifique
Multidrug-resistant E. Coli in wastewater sources: a comparative study and identification of resistance hotspots
Abstract Background This work aims to study the patterns of resistance to antibiotics in wastewater samples collected from hospitals, the …
Article scientifique
Filamentous prophages in the genomes of Acinetobacter baumannii from egypt: impact on biofilm formation and the potential to induce enterotoxicity
Filamentous phages (FPs) have been recently isolated from Acinetobacter baumannii. While FPs are known to modulate the virulence of some …
Article scientifique
Fexofenadine HCl enhances growth, biofilm, and lactic acid production of Limosilactobacillus reuteri and Bifidobacterium longum: implications for allergy treatment
BACKGROUND: It is evident that various drugs influence the gut microbiota, yet the precise mechanism driving these effects remain ambiguous. …
Article scientifique
Validation of stool and blood analysis compared to Inv A and ttr based direct blood qPCR assay as diagnostic tools for typhoid fever
BACKGROUND: The development of molecular techniques, such as polymerase chain reaction (qPCR), provides a promising approach for detecting S. enterica …
Article scientifique
Emergence of extensively drug-resistant Klebsiella pneumoniae from broiler chickens and clinical samples in Egypt
BACKGROUND: Klebsiella pneumoniae (K. pneumoniae) is an opportunistic pathogen belonging to Enterobacteriaceae family. It is present in the intestinal tract …
Article scientifique
Investigating the potential antibacterial, anti-biofilm, wound healing and anti-inflammatory activity of the extract of Aspergillus niger endophyte isolated from cucumber leaves: in vitro and in vivo study
BACKGROUND: Endophytic fungi are a vast inventory of bioactive compounds, offering potent, cost-effective, renewable, and low-toxicity alternatives for therapeutic applications. …
Article scientifique
Combatting biofilm formation of Klebsiella pneumoniae and Bacillus subtilis clinical strains from the oral cavity using biogenic Se-NPs: molecular docking simulation and cytotoxic effects on HepG2 cancer cells
Abstract Bacterial biofilms are one of the primary causes of pathogenic activity in the oral environment; they adhere to both …
Article scientifique
Evidence of microbiome contribution to the escalation of pyrethroid resistance in the major malaria vectors Anopheles gambiae s.s. and Anopheles funestus s.s
BACKGROUND: Exacerbation of pyrethroid resistance severely jeopardises the effectiveness of malaria vector control efforts. However, the mechanisms enabling the vectors …
Article scientifique
Fundamental changes in the antimicrobial resistance profile of Klebsiella quasipneumoniae ATCC 700603 in response to meropenem stress
Abstract Background Klebsiella is one of the most challenging superbugs having a high tendency to acquire rapid resistance to many …