31 publication(s) trouvée(s)
Article scientifique
The oral microbiota in oral squamous cell carcinoma: unravelling mechanisms and clinical potential
Originating in the mucosal lining of the mouth, oral squamous cell carcinoma is the most common malignancy of the head …
Article scientifique
Cracking the shield: oncolytic viruses versus the tumor-immune fortress
Oncolytic viruses (OVs) have emerged as a promising cancer therapy due to their natural selectivity to replicate in and destroy …
Article scientifique
Metabolomics reveals the therapeutic efficacy of liposomal resvida in endometrial cancer through regulating autophagy-related gene expression
Endometrial cancer (EC) is the fourth most abundant gynecological cancer. There is an increase in the incidence of mortality from …
Article scientifique
Diagnostic and therapeutic potential of exosomal circRNAs in cancer: decoding the circular code toward precision medicine
Circular RNAs (circRNAs), a unique class of non-coding RNAs, have gained attention due to their stable closed-loop structure and involvement …
Article scientifique
Characterization and comparative profiling of piRNAs in serum biopsies of pediatric Wilms tumor patients
Piwi-interacting RNAs (piRNAs) are small non-coding RNAs involved in transposon silencing and linked to cancer progression. However, their role in …
Article scientifique
Harnessing exosomes for targeted drug delivery systems to combat brain cancer
Brain cancer remains a significant challenge in the field of oncology, primarily because of its aggressive nature and the limited …
Article scientifique
Pan-inhibition of the three H2S synthesizing enzymes restrains tumor progression and immunosuppression in breast cancer
Abstract Background Hydrogen sulfide (H 2 S) is a significant endogenous mediator that has been implicated in the progression of …
Article scientifique
The emerging roles of sphingosine 1-phosphate and SphK1 in cancer resistance: a promising therapeutic target
Cancer chemoresistance is a problematic dilemma that significantly restrains numerous cancer management protocols. It can promote cancer recurrence, spreading of …
Article scientifique
Bladder cancer: therapeutic challenges and role of 3D cell culture systems in the screening of novel cancer therapeutics
Bladder cancer (BC) is the sixth most common worldwide urologic malignancy associated with elevated morbidity and mortality rates if not …
Article scientifique
BRAFV600E mutational status assessment in cutaneous melanocytic neoplasms in a group of the Egyptian population
Abstract Background Melanocytic neoplasms range from banal nevi to malignant melanomas. The genetic background has been extensively studied in the …
Article scientifique
Genetic profiling of different phenotypic subsets of breast cancer stem cells (BCSCs) in breast cancer patients
Abstract Background Breast cancer stem cells (BCSCs) have a crucial role in breast carcinogenesis, development, and progression. The aim of …
Article scientifique
Rise of the natural red pigment ‘prodigiosin’ as an immunomodulator in cancer
Cancer is a heterogeneous disease with multifaceted drug resistance mechanisms (e.g., tumour microenvironment [TME], tumour heterogeneity, and immune evasion). Natural …
Article scientifique
Pomegranate juice and punicalagin-mediated chemoprevention of hepatocellular carcinogenesis via regulating miR-21 and NF-κB-p65 in a rat model
BACKGROUND: Hepatocellular carcinoma (HCC) is the most common neoplasm among primary liver malignancies, accounting for 70%-85% of total liver cancer …
Article scientifique
Induction of oxidative DNA damage, cell cycle arrest and p53 mediated apoptosis by calcium titanate nanoparticles in MCF-7 breast cancer cells
Abstract Background The distinctive properties and high activity of calcium titanate nanoparticles (CaTiO3-NPs) increase their use in many products. However, …
Article scientifique
Notch-associated lncRNAs profiling circuiting epigenetic modification in colorectal cancer
BACKGROUND: Colorectal cancer (CRC) is one of the most prevalent digestive cancers, ranking the 2nd cause of cancer-related fatality worldwide. …
Article scientifique
Antitumor immunity and therapeutic properties of marine seaweeds-derived extracts in the treatment of cancer
Abstract Marine seaweeds are important sources of drugs with several pharmacological characteristics. The present study aims to evaluate the antitumor …
Erratum
Correction to: Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization
An amendment to this paper has been published and can be accessed via the original article.
Article scientifique
Genomic profiling of colorectal cancer with isolated lung metastasis
BACKGROUND: Metastasis is a major cause of failed colorectal cancer (CRC) treatment. While lung metastasis (LM) is observed in 10-15% …
Article scientifique
Modulation of doxorubicin-induced expression of the multidrug resistance gene in breast cancer cells by diltiazem and protection against cardiotoxicity in experimental animals
BACKGROUND: Doxorubicin (DOX) is one of the most important anticancer agents used in treating breast cancer. However, chronic cardiotoxicity and …
Article scientifique
In silico analysis excavates potential biomarkers by constructing miRNA-mRNA networks between non-cirrhotic HCC and cirrhotic HCC
Mounting evidences have demonstrated that HCC patients with or without cirrhosis possess different clinical characteristics, tumor development and prognosis. However, …
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