10 publication(s) trouvée(s)
Article scientifique
Genetic Susceptibility to Allergic Rhinitis: Impact of IL-4 Rs2243250 Polymorphism on Inflammatory Markers and Leukocyte Profiles
Background/Aims: Allergic rhinitis is a common chronic inflammatory disease affecting millions of people worldwide and substantially impairing quality of life. …
Article scientifique
Association Between DRD4 rs747302 and VNTR Polymorphisms and Drug Addiction in An Iraqi Population
BACKGROUND/AIMS: Drug addiction is a neuropsychiatric disorder characterised by compulsive drug-seeking behaviour notwithstanding adverse consequences. This work seeks to address …
Article scientifique
Post-Acute COVID-19 Pathophysiology: Cellular Stress Responses, Immune Dysregulation, and Biochemical Signatures in Recovery Phase
BACKGROUND/AIMS: Post-acute COVID-19 syndrome (PACS) presents with persistent symptoms such as fatigue, dyspnea, and cognitive impairment, even after apparent clinical …
Article scientifique
Bone Marrow Mesenchymal Stem Cells Promote Repairing the Bruised Tissue via Regulating mRNA Expression of Molecular Biomarkers and the Apoptotic Rate
BACKGROUND/AIMS: Bruise is the extravasation of blood that may be mild or severe. Bone marrow mesenchymal stem cells (BM-MSCs) are …
Article scientifique
Spastic Paraplegia 20 and Serine/Threonine Protein Kinase 31 Expression for the Detection of Colorectal Cancer
BACKGROUND/AIMS: Genetic alterations, including changes in the expression of spastic paraplegia 20 (SPG20) and serine/threonine protein kinase 31 (STK31), may …
Article scientifique
Enhanced Eryptosis in Glucose-6-Phosphate Dehydrogenase Deficiency
BACKGROUND/AIMS: Defects in the Glucose-6-Phosphate Dehydrogenase (G6PD) enzyme enhance cellular oxidative damage, thus impairing erythrocytes and radically shortening their lifespan. …
Article scientifique
Biochemical, Cellular, and Proteomic Characterization of Hereditary Spherocytosis Among Tunisians
BACKGROUND/AIMS: Hereditary Spherocytosis (HS) is the most common erythrocyte membrane disorder causing hemolytic anemia. The wide heterogeneity of both clinical …
Article scientifique
Small Molecule Glycomimetics Inhibit Vascular Calcification via c-Met/Notch3/HES1 Signalling
BACKGROUND/AIMS: Vascular calcification represents a huge clinical problem contributing to adverse cardiovascular events, with no effective treatment currently available. Upregulation …
Article scientifique
Analysis of Lamin B1, Vimentin and Anti-Ku86 as Prospective Biomarkers of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Infection
BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) is the fifth most common malignancy and most frequently develops in patients with cirrhosis. Surveillance strategies …
Article scientifique
CaMKII Modulates the Cardiac Transient Outward K+ Current through its Association with Kv4 Channels in Non-Caveolar Membrane Rafts
BACKGROUND/AIMS: /calmodulin-dependent protein kinase II (CaMKII) is restricted to lipid rafts and whether the interactions observed in rat cardiomyocytes also …