56 publication(s) trouvée(s)
Article scientifique
Revisiting the African mtDNA landscape through complete mitochondrial genomes
Africa harbors the richest diversity of mitochondrial DNA lineages, reflecting its central role in human evolutionary history. Early studies of …
Article scientifique
Major features of parasite adaptation revealed by genomes of Plasmodium falciparum population samples archived for over 50 years
Understanding evolution of human pathogens requires looking beyond the effects of recent interventions. To study malaria parasites prior to widespread …
Article scientifique
Deciphering the genomic signatures of climate vulnerability across 77 sheep breeds
Abstract Among domesticated species, sheep ( Ovis aries ) have achieved a wide geographic distribution due to their mobility, rusticity …
Article scientifique
Comparative genomics of blood and faecal E. coli and K. pneumoniae isolates from neonates with bloodstream infections in Tanzania
Bloodstream infections (BSIs) are a major cause of hospitalisation and death for children under the age of five in sub-Saharan …
Article scientifique
Evaluating the early diversification of Yersinia pestis and its phylogeographic expansion over 96 years of evolution in Madagascar
Madagascar is the most plague-affected country globally, yet the phylogenetic diversity of Yersinia pestis in this country remains insufficiently characterized. …
Article scientifique
Genomic analysis of Plasmodium vivax field isolates circulating in sub-Saharan Africa
Plasmodium vivax malaria is a major public health problem outside sub-Saharan Africa. However, an increasing number of P. vivax infections …
Article scientifique
A test of ecophysiological theories on tropical forest functional traits along a VPD gradient
Forest primary production is a crucial process for both ecosystem functioning and global carbon cycling. Primary production responds to both …
Article scientifique
Modelling the effects of diurnal temperature variation on malaria infection dynamics in mosquitoes
Mosquito infection experiments that characterise how sporogony changes with temperature are increasingly being used to parameterise malaria transmission models. In …
Article scientifique
Continent-wide genomic analysis of the African buffalo (Syncerus caffer)
The African buffalo (Syncerus caffer) is a wild bovid with a historical distribution across much of sub-Saharan Africa. Genomic analysis …
Article scientifique
Selective deforestation and exposure of African wildlife to bat-borne viruses
Proposed mechanisms of zoonotic virus spillover often posit that wildlife transmission and amplification precede human outbreaks. Between 2006 and 2012, …
Article scientifique
Compromise or choose: shared movement decisions in wild vulturine guineafowl
Shared-decision making is beneficial for the maintenance of group-living. However, little is known about whether consensus decision-making follows similar processes …
Article scientifique
Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity
Abstract Bacterial capsular polysaccharides are important vaccine immunogens. However, the study of polysaccharide-specific immune responses has been hindered by technical …
Article scientifique
Bioinoculants as a means of increasing crop tolerance to drought and phosphorus deficiency in legume-cereal intercropping systems
Ensuring plant resilience to drought and phosphorus (P) stresses is crucial to support global food security. The phytobiome, shaped by …
Article scientifique
A diminutive new basilosaurid whale reveals the trajectory of the cetacean life histories during the Eocene
Soon after whales originated from small terrestrial artiodactyl ancestors, basal stem forms (archaeocetes) came to inhabit more specialized aquatic ecologies …
Article scientifique
Human subsistence and signatures of selection on chemosensory genes
Chemosensation (olfaction, taste) is essential for detecting and assessing foods, such that dietary shifts elicit evolutionary changes in vertebrate chemosensory …
Article scientifique
Human blood neutrophils generate ROS through FcγR-signaling to mediate protection against febrile P. falciparum malaria
Blood phagocytes, such as neutrophils and monocytes, generate reactive oxygen species (ROS) as a part of host defense response against …
Article scientifique
Targeted and whole-genome sequencing reveal a north-south divide in P. falciparum drug resistance markers and genetic structure in Mozambique
Mozambique is one of the four African countries which account for over half of all malaria deaths worldwide, yet little …
Article scientifique
Future-proofing ecosystem restoration through enhancing adaptive capacity
Social-ecological ecosystem restoration involves interacting challenges, including climate change, resource overexploitation and political instability. To prepare for these and other …
Article scientifique
Rickettsia felis DNA recovered from a child who lived in southern Africa 2000 years ago
The Stone Age record of South Africa provides some of the earliest evidence for the biological and cultural origins of …
Article scientifique
Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community
Cognitive function is an indicator for global physical and mental health, and cognitive impairment has been associated with poorer life …
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