31 publication(s) trouvée(s)
Article scientifique
New insights into Notch signaling as a crucial pathway of pancreatic cancer stem cell behavior by chrysin-polylactic acid-based nanocomposite
Pancreatic cancer is an extremely deadly illness for which there are few reliable treatments. Recent research indicates that malignant tumors …
Article scientifique
Innovative laboratory techniques shaping cancer diagnosis and treatment in developing countries
Cancer is a major global health challenge, with approximately 19.3 million new cases and 10 million deaths estimated by 2020. …
Article scientifique
Bilateral adrenal neuroblastoma: peculiar pattern of a rare pediatric presentation
BACKGROUND: Bilateral suprarenal neuroblastoma (BSN) is a rare presentation. Few previously published literature showed BSN patients to have favorable pattern …
Article scientifique
Circulating tumor cells clusters and their role in Breast cancer metastasis; a review of literature
Breast cancer is a significant and deadly threat to women globally. Moreover, Breast cancer metastasis is a complicated process involving …
Article scientifique
Histological types of brain tumors diagnosed at the Kenyatta National Hospital between 2016 and 2019: a retrospective study
PURPOSE: To determine the histological types of brain tumors diagnosed at the Kenyatta National Hospital, Nairobi, Kenya. METHODS: This retrospective …
Article scientifique
The potential immuno-stimulating effect of curcumin, piperine, and taurine combination in hepatocellular carcinoma; a pilot study
BACKGROUND: This is a phase II clinical trial to investigate the immunotherapeutic effect of Curcumin, Piperine, and Taurine (CPT) combination …
Article scientifique
Antitumor activity of 5-fluorouracil polymeric nanogel synthesized by gamma radiation on a rat model of colon carcinoma: a proposed mechanism
The use of 5-fluorouracil (5-FU) is associated with multifaceted challenges and poor pharmacokinetics. Accordingly, our study was designed to prepare …
Article scientifique
New thiophene derivative augments the antitumor activity of γ-irradiation against colorectal cancer in mice via anti-inflammatory and pro-apoptotic pathways
BACKGROUND: Colorectal cancer (CRC) is one of the most common types of cancer worldwide and the second cause of cancer-related …
Article scientifique
New fluorobenzamidine exerts antitumor activity against breast cancer in mice via pro-apoptotic activity
BACKGROUND: Breast cancer is one of the leading causes of cancer-related morbidities. The present study aimed to evaluate the efficacy …
Article scientifique
Genetic variation in FOXP3 and ROR-γ genes in pediatric acute lymphocytic leukemia (ALL) patients: correlation with associated cytokines
BACKGROUND: FOXP3 and ROR-γ genes are master regulators of the Treg and Th17 differentiation, respectively. This work was planned to …
Article scientifique
Neuroimmune crosstalk and its impact on cancer therapy and research
Cancer is a major health problem as it is the first or second leading cause of death worldwide. The global …
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