185 publication(s) trouvée(s)
Article scientifique
A DNA vaccine candidate provides protection against Rift Valley Fever virus in sheep under natural field conditions
Rift Valley Fever virus (RVFV) is a mosquito-borne zoonotic pathogen, that causes significant morbidity and mortality in livestock, including high …
Article scientifique
A landscape review with novel criteria to evaluate microbial drivers for cancer: priorities for innovative research targeting excessive cancer mortality in sub-Saharan Africa
The escalating cancer burden in Sub-Saharan Africa (SSA), with projected doubling of incidence and mortality by 2040, necessitates innovative, cost-effective …
Article scientifique
Population structure, resistome, and virulome of Staphylococcus chromogenes strains from milk of subclinical bovine mastitis in South Africa
Introduction Staphylococcus chromogenes are commonly found in intramammary infections associated with bovine subclinical mastitis in dairy cattle, yet their genomic …
Article scientifique
Plasma protein biomarkers of Plasmodium falciparum infection in pregnant women: a high-throughput proteomics study
Introduction Pregnant women in sub-Saharan Africa face heightened susceptibility to Plasmodium falciparum malaria, with placental sequestration driving adverse outcomes. The …
Article scientifique
Eco-friendly silver nanoparticles from garlic: a novel therapeutic approach for treating Escherichia fergusonii wound infections
Introduction Complicated wound infections pose a significant challenge to patient recovery and healthcare systems, particularly due to the emergence of …
Article scientifique
First report of Crimean-Congo hemorrhagic fever virus exposure in human and livestock populations, Center Region, Cameroon
Crimean-Congo hemorrhagic fever (CCHF) is a widespread, tick-borne viral infection present in many African countries. Its epidemiology and impact on …
Article scientifique
IFIT2-induced transcriptomic changes in Mycobacterium tuberculosis infected macrophages
Interferon-induced protein with tetratricopeptide repeat 2 (IFIT2) is known for its antiviral activity and has recently been implicated in the …
Article scientifique
Can fungal endophytes suppress Trialeurodes vaporariorum and the transmission of tomato infectious chlorosis and chlorosis viruses in field conditions?
Field trials were conducted for two seasons in two experimental sites (Mwea in Kirinyaga and Ngoliba in Kiambu counties of …
Article scientifique
Bacterial blood microbiome of Mastomys rodents: implications for disease spill-over at the animal-human interface within the Bushbuckridge-East community, South Africa
The Bushbuckridge-East community in Mpumalanga Province, South Africa is bordered by nature reserves, including the Manyeleti Game Reserve. Murid rodents …
Article scientifique
Application of microphysiological systems to unravel the mechanisms of schistosomiasis egg extravasation
Despite decades of control efforts, the prevalence of schistosomiasis remains high in many endemic regions, posing significant challenges to global …
Article scientifique
Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections?
This review article discusses the role of vascular endothelial growth factor A (VEGF-A) in the pathogenesis of SARS-CoV-2 and HIV …
Éditorial
Editorial: Mpox: understanding the scientific gaps to combat the threat
The recent increase in mpox cases has led to critical inquiries regarding the virus's etiology, evolution, and transmission dynamics. The …
Article scientifique
Prevalence and clinical correlates of Gardnerella spp., Fannyhessea vaginae, Lactobacillus crispatus and L. iners in pregnant women in Bukavu, Democratic Republic of the Congo
Background Gardnerella is a key pathogen in bacterial vaginosis (BV), but the role of the different Gardnerella species remains unclear. …
Article scientifique
Hexagonal zinc oxide nanoparticles: a novel approach to combat multidrug-resistant Enterococcus faecalis biofilms in feline urinary tract infections
Introduction Enterococcus faecalis, a common inhabitant of the feline gastrointestinal tract, has emerged as a significant pathogen causing urinary tract …
Article scientifique
Herpes simplex virus type 2 in sub-Saharan Africa and the potential impact of helminth immune modulation
Herpes simplex virus type 2 (HSV-2) and helminth infections are among the most widespread infectious diseases in sub-Saharan Africa (SSA). …
Article scientifique
Salmonella Typhi Haplotype 58 biofilm formation and genetic variation in isolates from typhoid fever patients with gallstones in an endemic setting in Kenya
Although typhoid fever has largely been eliminated in high-income countries, it remains a major global public health concern especially among …
Article scientifique
Silver nanoparticles loaded with pomegranate peel extract and hyaluronic acid mediate recovery of cutaneous wounds infected with Candida albicans
Smart innovative nanocomposites based on active ingredients and metallic nanoparticles with effective wound healing and antifungal properties are efficient in …
Article scientifique
Tuberculosis morbidity and mortality during the COVID-19 pandemic: a life-threatening complex challenge
Worldwide, an estimated 10.6 million people (95% UI: 9.9-11.4 million) fell ill with TB worldwide in 2022, up from 10.3 …
Article scientifique
Effects of four potent entomopathogenic fungal isolates on the survival and performance of Telenomus remus, an egg parasitoid of fall armyworm
Fall armyworm (FAW), Spodoptera frugiperda is a generalist pest known to feed on more than 300 plant species, including major …
Article scientifique
Approved drugs successfully repurposed against Leishmania based on machine learning predictions
Drug repurposing is a promising approach towards the discovery of novel treatments against Neglected Tropical Diseases, such as Leishmaniases, presenting …