185 publication(s) trouvée(s)
Article scientifique
Molecular Detection of Insecticide Resistance Mutations in Anopheles gambiae from Sierra Leone Using Multiplex SNaPshot and Sequencing
Vector control interventions including long-lasting insecticidal nets and indoor residual spraying are important for malaria control and elimination. And effectiveness …
Article scientifique
Distinct Immune Profiles of Exhausted Effector and Memory CD8+ T Cells in Individuals With Filarial Lymphedema
CD8+ T cells are crucial for the clearance of viral infections, and current research begins to highlight their importance in …
Article scientifique
Antibiotic Resistance Pattern of Extended Spectrum Beta Lactamase Producing Escherichia coli Isolated From Patients With Urinary Tract Infection in Morocco
Extended-spectrum β-lactamases producing Escherichia coli (ESBL-EC) lend resistance to most β-lactam antibiotics. Because of limited treatment options, ESBL-EC infections are …
Article scientifique
Virulence and Antibiotic Resistance Characteristics of Vibrio Isolates From Rustic Environmental Freshwaters
The study investigated the occurrence of antimicrobial resistance genes and virulence determinants in Vibrio species recovered from different freshwater sheds …
Article scientifique
Emergence of Multidrug-Resistant Escherichia coli Producing CTX-M, MCR-1, and FosA in Retail Food From Egypt
In this study, multidrug-resistant (MDR) Escherichia coli isolates from retail food and humans assigned into similar Multilocus Sequence Types (MLST) …
Article scientifique
Machine Learning Uses Chemo-Transcriptomic Profiles to Stratify Antimalarial Compounds With Similar Mode of Action
The rapid development of antimalarial resistance motivates the continued search for novel compounds with a mode of action (MoA) different …
Article scientifique
Candida albicans SET3 Plays a Role in Early Biofilm Formation, Interaction With Pseudomonas aeruginosa and Virulence in Caenorhabditis elegans
The yeast Candida albicans exhibits multiple morphologies dependent on environmental cues. Candida albicans biofilms are frequently polymicrobial, enabling interspecies interaction …
Article scientifique
ATI-2307 Exhibits Equivalent Antifungal Activity in Cryptococcus neoformans Clinical Isolates With High and Low Fluconazole IC50
Half maximal inhibitory concentrations (IC 50 ) to the experimental drug ATI-2307 and complete inhibition (IC 90 ) of the …
Article scientifique
Detection of Mycobacterium tuberculosis Complex Bacilli and Nucleic Acids From Tongue Swabs in Young, Hospitalized Children
Diagnosis of tuberculosis in pediatric patients remains challenging due to inherent difficulties associated with obtaining respiratory samples for molecular and …
Article scientifique
Dysbiotic Fecal Microbiome in HIV-1 Infected Individuals in Ghana
HIV-1 infected individuals under antiretroviral therapy can control viremia but often develop non-AIDS diseases such as cardiovascular and metabolic disorders. …
Article scientifique
Rekindling of a Masterful Precedent; Bacteriophage: Reappraisal and Future Pursuits
Antibiotic resistance is exuberantly becoming a deleterious health problem world-wide. Seeking innovative approaches is necessary in order to circumvent such …
Article scientifique
Dengue Virus Infection in Sub-Saharan Africa Between 2010 and 2020: A Systematic Review and Meta-Analysis
Dengue virus (DENV) infection has garnered a global interest in the past few decades. Nevertheless, its epidemiology in certain developing …
Article scientifique
Metabolic Implications of Oxidative Stress and Inflammatory Process in SARS-CoV-2 Pathogenesis: Therapeutic Potential of Natural Antioxidants
COVID-19 is a zoonotic disease with devastating economic and public health impacts globally. Being a novel disease, current research is …
Article scientifique
Transcription Factors Interplay Orchestrates the Immune-Metabolic Response of Leishmania Infected Macrophages
Leishmaniasis is a group of heterogenous diseases considered as an important public health problem in several countries. This neglected disease …
Article scientifique
Comparison of Two Approaches for the Metataxonomic Analysis of the Human Milk Microbiome
Recent work has demonstrated the existence of large inter-individual and inter-population variability in the microbiota of human milk from healthy …
Article scientifique
Genome-Wide Scans for Ghanaian Plasmodium falciparum Genes Under Selection From Local and Chinese Host Populations
Initial malarial infection mostly causes symptomatic illness in humans. Infection that is not fatal induces complete protection from severe illness …
Article scientifique
HIV-1 Infection Is Associated With Increased Prevalence and Abundance of Plasmodium falciparum Gametocyte-Specific Transcripts in Asymptomatic Adults in Western Kenya
As morbidity and mortality due to malaria continue to decline, the identification of individuals with a high likelihood of transmitting …
Article scientifique
High Prevalence of Multidrug-Resistant Clostridioides difficile Following Extensive Use of Antimicrobials in Hospitalized Patients in Kenya
Introduction Clostridioides difficile is a neglected pathogen in many African countries as it is generally not regarded as one of …
Article scientifique
The Macrophage Response to Mycobacterium tuberculosis and Opportunities for Autophagy Inducing Nanomedicines for Tuberculosis Therapy
The major causative agent of tuberculosis (TB), i.e.,Mycobacterium tuberculosis (Mtb), has developed mechanisms to evade host defense responses and persist …
Article scientifique
Plasmodium falciparum DHFR and DHPS Mutations Are Associated With HIV-1 Co-Infection and a Novel DHPS Mutation I504T Is Identified in Western Kenya
Antifolate resistance is significant in Kenya and presumed to result from extensive use and cross-resistance between antifolate antimalarials and antibiotics, …