16 publication(s) trouvée(s)
Éditorial
Editorial: Role of microbiota in neurocognitive disorders: a developmental origin perspective
human mind is now considered as an extension of the microbial ecosystem, shaped by the interaction between the human genome …
Article scientifique
Effects of ethanol leaf extract of Spondias mombin on scopolamine-induced hippocampal neurodegeneration in adult male Wistar rats: evidence from behavioral, biochemical, histological, and immunohistochemical analyses
Previous studies have demonstrated that phytochemicals present in Spondias mombin leaves possess neuro-regenerative and neuroprotective potentials. This study therefore evaluated …
Article scientifique
Gut mycobiome and neuropsychiatric disorders: insights and therapeutic potential
Background: The human gut mycobiome, a minor but integral component of the gut microbiome, has emerged as a significant player …
Article scientifique
The gut-eye axis: the retinal/ocular degenerative diseases and the emergent therapeutic strategies
The interplay between human microbiota and various physiological systems has garnered significant attention in recent years. The gut microbiota plays …
Article scientifique
Orexins in apoptosis: a dual regulatory role
The orexins, also referred to as hypocretins, are neuropeptides that originate from the lateral hypothalamus (LH) region of the brain. …
Article scientifique
Tempol improves optic nerve histopathology and ultrastructures in cisplatin-induced optic neuropathy in rats by targeting oxidative stress—Endoplasmic reticulum stress—Autophagy signaling pathways
Introduction Optic neuropathy is an affection of the optic neurons, which ends with blindness and occurs either primarily due to …
Article scientifique
Unveiling the interplay between NSAID-induced dysbiosis and autoimmune liver disease in children: insights into the hidden gateway to autism spectrum disorders. Evidence from ex vivo, in vivo, and clinical studies
Autism spectrum disorders (ASD) represent a diverse group of neuropsychiatric conditions, and recent evidence has suggested a connection between ASD …
Article scientifique
Bifurcation analysis of motoneuronal excitability mechanisms under normal and ALS conditions
Introduction Bifurcation analysis allows the examination of steady-state, non-linear dynamics of neurons and their effects on cell firing, yet its …
Article scientifique
Astrocytes profiling in acute hepatic encephalopathy: Possible enrolling of glial fibrillary acidic protein, tumor necrosis factor-alpha, inwardly rectifying potassium channel (Kir 4.1) and aquaporin-4 in rat cerebral cortex
Hepatic encephalopathy (HE) is a neurological disarray manifested as a sequel to chronic and acute liver failure (ALF). A potentially …
Article scientifique
Microglial Implications in SARS-CoV-2 Infection and COVID-19: Lessons From Viral RNA Neurotropism and Possible Relevance to Parkinson’s Disease
Since December 2019, humankind has been experiencing a ravaging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak, the second coronavirus …
Article scientifique
Cellular and Molecular Targets of Waterbuck Repellent Blend Odors in Antennae of Glossina fuscipes fuscipes Newstead, 1910
Insects that transmit many of the world’s deadliest animal diseases, for instance trypanosomosis, find their suitable hosts and avoid non-preferred …
Article scientifique
The Involvement of Aβ42 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction
Alzheimer's disease (AD) is the most common form of dementia and is distinguished from other dementias by observation of extracellular …
Article scientifique
Direct Current Coupled Recordings of Cortical Spreading Depression Using Silicone Probes
Electrophysiological assessment of infraslow (<0.1 Hz) brain activities such as cortical spreading depression (SD), which occurs in a number of …
Article scientifique
RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia
Transcripts for α9 and α10 nicotinic acetylcholine receptor (nAChR) subunits are found in diverse tissues. The function of α9α10 nAChRs …
Article scientifique
Postsynaptic GABA(B) Receptors Contribute to the Termination of Giant Depolarizing Potentials in CA3 Neonatal Rat Hippocampus
During development, hippocampal CA3 network generates recurrent population bursts, so-called Giant Depolarizing Potentials (GDPs). GDPs are characterized by synchronous depolarization …
Article scientifique
Myotonic Dystrophies: State of the Art of New Therapeutic Developments for the CNS
Myotonic dystrophies are multisystemic diseases characterized not only by muscle and heart dysfunction but also by CNS alteration. They are …