192 publication(s) trouvée(s)
Article scientifique
Facile exfoliation of natural talc into separated mesoporous magnesium silicate nano-sheets for effective sequestration of phosphate and nitrate ions: characterization and advanced modeling
Magnesium silicate nano-sheets were synthesized from natural talc by facile exfoliation and delamination methods as exfoliated product (EXTC) of 29.5 …
Erratum
Corrigendum: Antioxidant, Anti-Alzheimer’s, anticancer, and cytotoxic properties of peanut oil: in vitro, in silico, and GC-MS analysis
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Article scientifique
Molecular characterization, chemical profile and biological properties of essential oils from Chamaemelum nobile (L.) flowers of Morocco: in vitro and in silico studies
Introduction This study investigated the antioxidant, antimicrobial, and insecticidal properties of Chamaemelum nobile (L.) essential oil (CN-EO), harvested in Taounate, …
Article scientifique
In silico identification of the anticataract target of βB2-crystallin from Phaseolus vulgaris: a new insight into cataract treatment
Introduction: Severe protein clumping in the lens can block light and lead to vision issues in cataract patients. Recent studies …
Article scientifique
Therapeutic potential of Curcuma longa against monkeypox: antioxidant, anti-inflammatory, and computational insights
Background Monkeypox (Mpox) is a re-emerging zoonotic disease with limited therapeutic options, necessitating the exploration of novel antiviral agents. Curcuma …
Article scientifique
Machine learning and molecular dynamics simulations predict potential TGR5 agonists for type 2 diabetes treatment
Introduction: Treatment of type 2 diabetes (T2D) remains a significant challenge because of its multifactorial nature and complex metabolic pathways. …
Article scientifique
Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations
Introduction Ferula communis has demonstrated an abundance of pharmacological and antioxidative qualities. Methods This study investigates the antioxidant activity of …
Article scientifique
Design, synthesis, and apoptotic antiproliferative action of new benzimidazole/1,2,3-triazole hybrids as EGFR inhibitors
Introduction This work outlines the design, synthesis, and biological evaluation of a new series of benzimidazole/1,2,3-triazole hybrids as apoptotic antiproliferative …
Article scientifique
Evaluation of the anti-spasmodic activity of essential oils of Ammodaucus leucotrichus fruits and its main chemical component “perillaldehyde” on intestinal smooth muscle contractions of rodents: ex vivo and in silico approaches
Ethnopharmacological relevance In Moroccan traditional medicine, plants from the Apiaceae family are widely utilized in folk medicine to treat various …
Article scientifique
Chemical composition, antimicrobial, and antioxidant properties of essential oils from Artemisia herba-alba asso. and Artemisia huguetii caball. from Morocco: in vitro and in silico evaluation
Introduction: Morocco is home to a remarkable diversity of flora, including several species from the Artemisia genus. This study aims …
Article scientifique
Machine learning and molecular docking prediction of potential inhibitors against dengue virus
Introduction Dengue Fever continues to pose a global threat due to the widespread distribution of its vector mosquitoes, Aedes aegypti …
Éditorial
Editorial: Antibacterial effects and mode of action of new active substances against drug resistant pathogenic bacteria
Antibacterial effects and mode of action of new active substances against drug resistant pathogenic bacteria.Antimicrobial resistance (AMR) is still one …
Article scientifique
Prostruc: an open-source tool for 3D structure prediction using homology modeling
Introduction: Homology modeling is a widely used computational technique for predicting the three-dimensional (3D) structures of proteins based on known …
Article scientifique
New series of 4,6-diaryl pyrimidines: facile synthesis and antiproliferative activity as dual EGFR/VEGFR-2 inhibitors
Introduction We developed and produced a new series of 4,6-diaryl-pyrimidines 9–29 as antiproliferative agents targeting EGFR/VEGFR-2. Methods The antiproliferative efficacy …
Article scientifique
Phytochemical profiling and in silico evaluation of Artemisia absinthium compounds targeting Leishmania N-myristoyltransferase: molecular docking, drug-likeness, and toxicity analyses
Background Artemisia absinthium has long been recognized for its therapeutic properties against various diseases. Among these is leishmaniasis, a parasitic …
Article scientifique
Antioxidant potential, antimicrobial activity, polyphenol profile analysis, and cytotoxicity against breast cancer cell lines of hydro-ethanolic extracts of leaves of (Ficus carica L.) from Eastern Morocco
Introduction Many beneficial compounds found in fig leaves can be used in tea and medicine. These compounds aid with digestion, …
Article scientifique
Efficient phosphate removal from water using ductile cast iron waste: a response surface methodology approach
Water scarcity is a critical issue worldwide. This study explores a novel method for addressing this issue by using ductile …
Article scientifique
Physicochemical, steric, and energetic characterization of kaolinite based silicate nano-sheets as potential adsorbents for safranin basic dye: effect of exfoliation reagent and techniques
Kaolinite was subjected to advanced exfoliation processes to form separated nano-silicate sheets (EXK) with enhanced physicochemical properties as adsorbents. This …
Article scientifique
Formulation and characterization of cholesterol-based nanoparticles of gabapentin protecting from retinal injury
Introduction: This study aimed to prepare cholesterol and stearic acid-based solid lipid nanoparticles of gabapentin (GAB-SLNs) for protection against streptozotocin …
Article scientifique
Phytochemical profile, physicochemical, antioxidant and antimicrobial properties of Juniperus phoenicea and Tetraclinis articulate: in vitro and in silico approaches
Introduction This research aims to explore the molecular composition, antioxidant capabilities, and antibacterial effects of the essential oils from Tetraclinis …