8 publication(s) trouvée(s)
Article scientifique
Synthesis of copper oxide nanoparticles using Aloe vera leaf extract and their antibacterial activity against methicillin-resistant Staphylococcus aureus and multi-drug resistant Klebsiella pneumoniae
The global interest in nanotechnology has significantly increased in recent years as a necessity to create new and natural antibacterial …
Article scientifique
Redefining the geography of pharmaceutical innovation: Kelly Chibale as a harbinger for integrated drug discovery in Africa
Drug discovery has historically been concentrated in high-income countries, creating a geographically asymmetric pharmaceutical ecosystem in which regions such as …
Article scientifique
Probing the activity of BM212, an antimycobacterial, and its derivatives against multiple life cycle stages of Plasmodium falciparum
Introduction The emergence of resistance to frontline antimalarial drugs underscores the urgent need for new chemotypes capable of targeting multiple …
Article scientifique
Exploring deep learning approaches in anticancer drug design: a review of recent advances
Anticancer drug design plays a critical role in developing targeted therapies to combat the complexity and heterogeneity of cancer, a …
Article scientifique
Integrated in vivo and in silico evaluation of antimalarial compounds from Vernonia ambigua leaves identified by GC-MS profiling
Background Malaria remains a global health challenge, and the emergence of drug-resistant Plasmodium strains has necessitated the search for new …
Article scientifique
State-of-the-art strategies to prioritize Mycobacterium tuberculosis drug targets for drug discovery using a subtractive genomics approach
Tuberculosis remains one of the causes of death from a single infectious bacterium. The inappropriate use of antibiotics and patients’ …
Article scientifique
Artificial intelligence for antiviral drug discovery in low resourced settings: A perspective
Current antiviral drug discovery efforts face many challenges, including development of new drugs during an outbreak and coping with drug …
Article scientifique
The challenges and opportunities for the development of COVID-19 therapeutics and preparing for the next pandemic
The disease which is today known as COVID-19 is caused by severe acute respiratory. Syndrome coronavirus 2 (SARS-COV-2), was first …