65 publication(s) trouvée(s)
Article scientifique
Association between infant post-natal prophylaxis regimens and pretreatment HIV drug resistance in infected infants
Background Antiretroviral drugs for preventing mother-to-child transmission (PMTCT) can lead to NRTI resistance in infants who contract HIV despite prophylaxis. …
Article scientifique
High prevalence of human coronaviruses in rural and urban Ghana in the post-COVID-19 era
The prevalence and distribution of endemic human coronaviruses (HCoVs) in Ghana remain poorly characterized, particularly in the post-COVID-19 pandemic era. …
Article scientifique
Sociodemographic determinants and prevalence of metabolic risk factors and the metabolic syndrome among women aged 20–49 in kirinyaga county, Kenya
Introduction Globally, Noncommunicable diseases (NCDs) contribute to 75% of all deaths. The precursors to the development of NCDs include the …
Article scientifique
Mixed-strain infection and heteroresistance in drug-resistant tuberculosis: insights from a whole-genome sequencing pilot
Background: tuberculosis; Mtb) infections and heteroresistance are increasingly recognized as under-detected contributors to drug resistance dynamics. In high-burden rural settings …
Article scientifique
High prevalence of Q fever among patients clinically diagnosed with brucellosis in a Kenyan pastoralist community
Coxiella burnetii is a zoonotic bacterial agent responsible for Q fever in both humans and animals. Ruminants are the most …
Article scientifique
A Bayesian spline-augmented piecewise exponential model with spatial frailty for under-five mortality in Nigeria
Introduction: The Cox proportional hazards (PH) model is widely used in time-to-event research, but its validity depends on the PH …
Article scientifique
Spatial modeling of HIV prevalence in Malawi using generalized additive models
Introduction: Malawi has made substantial progress in HIV prevention and treatment, yet HIV prevalence remains unevenly distributed across the country. …
Article scientifique
Pan-continental spillover risk: integrated spatiotemporal, transmissibility and surveillance analysis of avian influenza a(H5N1) in Africa
Background The HPAI H5N1 panzootic represents a critical threat to human health in Africa, where traditional poultry systems and dense …
Article scientifique
The persistence and mortality of Lassa fever in Nigeria reflect systemic clinical and diagnostic challenges rather than viral reemergence alone
Each seasonal surge of Lassa fever deaths reignites a familiar question in Nigeria: has the virus become more dangerous?. The …
Article scientifique
HIV-1 late diagnosis in Cabo Verde: associated factors and implications for preventive strategies
Background: Late diagnosis of HIV infection remains a major public health challenge, associated with higher morbidity and mortality, ongoing transmission, …
Article scientifique
Ventilator-associated pneumonia among intensive care nurses: a multicenter cross-sectional study on knowledge and preventive measures in intensive care units of Mogadishu, Somalia
Background Ventilator-associated pneumonia (VAP) remains a major healthcare-associated infection in intensive care units (ICUs), and its prevention largely depends on …
Article scientifique
An epidemiological assessment of the distribution and sociodemographic burden of chronic diseases: a focus on hypertension, diabetes, and cardiovascular conditions
Background: Chronic diseases remain a major contributor to morbidity and mortality worldwide. Understanding the sociodemographic and behavioral factors associated with …
Article scientifique
Applications and implementation considerations for stepped-wedge designs in sub-Saharan Africa: a systematic review
Introduction: Stepped-wedge design (SWD) has gained prominence as a versatile research methodology, particularly in public health and implementation science, due …
Article scientifique
Vitamin D and the metabolic-associated steatotic liver disease—type 2 diabetes axis: a scoping-narrative review of global evidence and emerging perspectives for Sub-Saharan Africa
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) and Type 2 Diabetes Mellitus (T2DM) are rapidly emerging as twin epidemics in …
Article scientifique
Navigating sociocultural practices and traditions in HIV management: a review of African cultural barriers to achieving sustainable development goal target 3.3
The narrative review aimed to explore how the sociocultural belief systems influence the health-seeking behavior of individuals living with HIV …
Article scientifique
Hierarchical forecasting of COVID-19 cases in Africa using machine learning models
Introduction: The COVID-19 pandemic posed significant challenges for public health systems, especially in Africa, where data scarcity, inadequate healthcare infrastructure, …
Article scientifique
Low prevalence of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions in archived samples collected before and after nationwide malaria-RDT rollout in Kenya
Rapid and accurate malaria diagnosis is essential for effective treatment and malaria control. In Kenya, most malaria testing relies on …
Article scientifique
Climate-informed surveillance for climate-sensitive infectious diseases in Somalia: early warning systems, policy gaps, and preparedness priorities
Climate variability is reshaping infectious disease risk through ecological, environmental, social, and health-system pathways. However, its operational implications remain insufficiently …
Article scientifique
Needs assessment of the advanced Ghana field epidemiology and laboratory training program, April 2024: lessons learned and best practices
Background: The Ghana Field Epidemiology and Laboratory Training Program (GFELTP) trains skilled field epidemiologists to strengthen surveillance systems and respond …
Article scientifique
Syndemic geographic patterns of integrated diseases during the Libyan armed conflict; a new aspect for public health care intervention?
Introduction: Synedmic geographic analysis is new epidemiological tool used to implement crucial effective intervention to combat integrated diseases. This study …
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