227 publication(s) trouvée(s)
Article scientifique
Personalizing medicine in Africa: current state, progress and challenges
Personalized medicine has been identified as a powerful tool for addressing the myriad of health issues facing different health systems …
Article scientifique
Delineating intra-tumoral heterogeneity and tumor evolution in breast cancer using precision-based approaches
The burden of breast cancer continues to increase worldwide as it remains the most diagnosed tumor in females and the …
Article scientifique
The African Goat Improvement Network: a scientific group empowering smallholder farmers
The African Goat Improvement Network (AGIN) is a collaborative group of scientists focused on genetic improvement of goats in small …
Éditorial
Editorial: Building capacity for sickle cell disease research and healthcare
EDITORIAL article Front. Genet., 12 July 2023Sec. Genetics of Common and Rare Diseases Volume 14 - 2023 | https://doi.org/10.3389/fgene.2023.1226589
Article scientifique
Misclassified: identification of zoonotic transition biomarker candidates for influenza A viruses using deep neural network
Introduction: Zoonotic transition of Influenza A viruses is the cause of epidemics with high rates of morbidity and mortality. Predicting …
Article scientifique
Impact of Plasmodium falciparum infection on DNA methylation of circulating immune cells
The regulation of immune cell responses to infection is a complex process that involves various molecular mechanisms, including epigenetic regulation. …
Article scientifique
A review of multi-omics data integration through deep learning approaches for disease diagnosis, prognosis, and treatment
Accurate diagnosis is the key to providing prompt and explicit treatment and disease management. The recognized biological method for the …
Éditorial
Editorial: Application of meta-omics in biotechnology, environmental monitoring, and health
The advancement of meta-omics and its integration into a variety of fields of biotechnology, environmental monitoring, and health over the …
Article scientifique
Improving hydrocarbon toxicity tolerance in poultry: role of genes and antioxidants
Sustenance of smallholder poultry production as an alternative source of food security and income is imperative in communities exposed to …
Article scientifique
Regulating human genomic research in Africa: why a human rights approach is a more promising conceptual framework than genomic sovereignty
This article revisits the debate on the regulation of human genomic research, with a focus on Africa. The article comprehensively …
Article scientifique
Toward an open access genomics database of South Africans: ethical considerations
Genomics research holds the potential to improve healthcare. Yet, a very low percentage of the genomic data used in genomics …
Article scientifique
Identifying the genetic causes of developmental disorders and intellectual disability in Africa: a systematic literature review
Objective: Genetic variants cause a significant portion of developmental disorders and intellectual disabilities (DD/ID), but clinical and genetic heterogeneity makes …
Article scientifique
Gamma irradiation-induced genetic variability and its effects on the phenotypic and agronomic traits of groundnut (Arachis hypogaeaL.)
In order to increase genetic variability for the improvement of groundnut, two varieties, namely Kp29 and Fleur11, were treated with …
Éditorial
Editorial: Contribution of omics to our understanding of human-bacterial interplay in health and disease
Since their discovery by Antoni van Leeuwenhoek in 1676, bacterial microorganisms have not ceased to amaze by the impact they …
Article scientifique
Genome-wide identification, characterization, and validation of the bHLH transcription factors in grass pea
Background: The basic helix-loop-helix (bHLH) transcription factor is a vital component in plant biology, with a significant impact on various …
Article scientifique
Going to scale—From community-based to population-wide genetic improvement and commercialized sheep meat supply in Ethiopia
Community-based breeding programs (CBBPs) have shown, at pilot scale, to be effective and beneficial in achieving genetic progress and in …
Article scientifique
How to succeed in implementing community-based breeding programs: Lessons from the field in Eastern and Southern Africa
Breeding programs involving either centralized nucleus schemes and/or importation of exotic germplasm for crossbreeding were not successful and sustainable in …
Article scientifique
Promoter methylation might shift the balance of Galectin-3 & 12 expression in de novo adult acute myeloid leukemia patients
Acute myeloid leukemia (AML) was reported as the most common type of leukemia among adults. Galectins constitute a family of …
Article scientifique
Strategies to improve healthcare services for patients with sickle cell disease in Nigeria: The perspectives of stakeholders
Background: Sickle cell disease (SCD) continues to pose physical and psychosocial burdens to patients, caregivers and health workers. Stakeholder engagement …
Article scientifique
Genes and models for estimating genetic parameters for heat tolerance in dairy cattle
Dairy cattle are highly susceptible to heat stress. Heat stress causes a decline in milk yield, reduced dry matter intake, …