471 publication(s) trouvée(s)
Article scientifique
The COVID-19 Cytokine Storm; What We Know So Far
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the WHO. COVID-19 is transmitted …
Erratum
Corrigendum: Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme
[This corrects the article DOI: 10.3389/fimmu.2018.01557.].
Article scientifique
Maternal Latent Mycobacterium tuberculosis Does Not Affect the Infant Immune Response Following BCG at Birth: An Observational Longitudinal Study in Uganda
Background: BCG has low efficacy in tropical countries. We hypothesised that maternal latent Mycobacterium tuberculosis (M.tb) infection (LTBI) results in …
Article scientifique
Contrasting Inflammatory Signatures in Peripheral Blood and Bronchoalveolar Cells Reveal Compartment-Specific Effects of HIV Infection
The mechanisms by which HIV increases susceptibility to tuberculosis and other respiratory infections are incompletely understood. We used transcriptomics of …
Article scientifique
Global Repertoire of Human Antibodies Against Plasmodium falciparum RIFINs, SURFINs, and STEVORs in a Malaria Exposed Population
Clinical immunity to malaria develops after repeated exposure to Plasmodium falciparum parasites. Broadly reactive antibodies against parasite antigens expressed on …
Article scientifique
Neutrophils in Tuberculosis-Associated Inflammation and Lung Pathology
-the causative agent of tuberculosis (TB)-is not fully understood but involves immune responses within the pulmonary airways which can lead …
Article scientifique
The Biology of Lactoferrin, an Iron-Binding Protein That Can Help Defend Against Viruses and Bacteria
Lactoferrin is a nutrient classically found in mammalian milk. It binds iron and is transferred via a variety of receptors …
Éditorial
Commentary: An enzymatic pathway in the human gut microbiome that converts A to universal O type blood
GENERAL COMMENTARY article Front. Immunol., 28 April 2020Sec. Alloimmunity and Transplantation Volume 11 - 2020 | https://doi.org/10.3389/fimmu.2020.00772
Article scientifique
Plasmodium falciparum Merozoite Associated Armadillo Protein (PfMAAP) Is Apically Localized in Free Merozoites and Antibodies Are Associated With Reduced Risk of Malaria
Understanding the functional role of proteins expressed by Plasmodium falciparum is an important step towards unlocking potential targets for the …
Erratum
Corrigendum: Immune Responses to Gametocyte Antigens in a Malaria Endemic Population—The African falciparum Context: A Systematic Review and Meta-Analysis
[This corrects the article DOI: 10.3389/fimmu.2019.02480.].
Article scientifique
Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A
P27A is a novel synthetic malaria vaccine candidate derived from the blood stage Plasmodium falciparum protein Trophozoite Exported Protein 1 …
Article scientifique
Myeloid-Derived Suppressor Cells as Target of Phosphodiesterase-5 Inhibitors in Host-Directed Therapeutics for Tuberculosis
Resistance towards current and new classes of anti-tuberculosis (TB) antibiotics are emerging rapidly, thus innovative therapies focussed on host processes, …
Article scientifique
CD4 T Cells in Mycobacterium tuberculosis and Schistosoma mansoni Co-infected Individuals Maintain Functional TH1 Responses
Mycobacterium tuberculosis (Mtb) is a serious public health concern, infecting a quarter of the world and leading to 10 million …
Article scientifique
In utero Exposure to Maternal Chronic Inflammation Transfers a Pro-Inflammatory Profile to Generation F2 via Sex-Specific Mechanisms
Generational transfer of maladaptations in offspring have been reported to persist for multiple generations in conditions of chronic inflammation, metabolic …
Article scientifique
Newborn Screening for Primary Immunodeficiencies: The Gaps, Challenges, and Outlook for Developing Countries
Primary immunodeficiency diseases (PIDs) are genetically inherited diseases characterized by an increased susceptibility to infections, autoimmunity, lymphoproliferation, and malignancies. PIDs …
Article scientifique
Antimicrobial and Immunomodulatory Effect of Gum Arabic on Human and Bovine Granulocytes Against Staphylococcus aureus and Escherichia coli
Gum arabic (GA) is a traditional herbal medicine from Acacia Senegal (L) Willdenow trees, which consist of a complex mixture …
Article scientifique
Caveolin-1 Controls Vesicular TLR2 Expression, p38 Signaling and T Cell Suppression in BCG Infected Murine Monocytic Myeloid-Derived Suppressor Cells
Monocytic myeloid-derived suppressor cells (M-MDSCs) and granulocytic MDSCs (G-MDSCs) have been found to be massively induced in TB patients as …
Article scientifique
Capacity to Elicit Cytotoxic CD8 T Cell Activity Against Mycobacterium avium subsp. paratuberculosis Is Retained in a Vaccine Candidate 35 kDa Peptide Modified for Expression in Mammalian Cells
Studies focused on development of an attenuated vaccine against Mycobacterium avium subsp. paratuberculosis (Map), the causative agent of paratuberculosis (Ptb) …
Article scientifique
Negative Association of Interleukin-33 Plasma Levels and Schistosomiasis Infection in a Site of Polyparasitism in Rural Cameroon
Background: This study aimed to investigate the association of plasma levels of IL-33, a mucosal alarmin known to elicit type-2 …
Article scientifique
Cytotoxic T Cell-Derived Granzyme B Is Increased in Severe Plasmodium Falciparum Malaria
In Plasmodium falciparum malaria, CD8+ T cells play a double-edged role. Liver-stage specific CD8+ T cells can confer protection, as …