46 publication(s) trouvée(s)
Article scientifique
Probing the Structural Dynamics of the Plasmodium falciparum Tunneling-Fold Enzyme 6-Pyruvoyl Tetrahydropterin Synthase to Reveal Allosteric Drug Targeting Sites
The folate de novo synthesis pathway is a well-established drug target in the treatment of many infectious diseases. Antimalarial antifolate …
Article scientifique
Can CRISPR/Cas Technology Be a Felicitous Stratagem Against the COVID-19 Fiasco? Prospects and Hitches
The current global debacle of COVID-19, spelled by SARS-CoV-2 needs no elaboration. With incessant and constantly clambering number of deaths …
Article scientifique
Pinpointing Cell Identity in Time and Space
Mammalian cells display a broad spectrum of phenotypes, morphologies, and functional niches within biological systems. Our understanding of mechanisms at …
Article scientifique
Novel Quinazolin-2,4-Dione Hybrid Molecules as Possible Inhibitors Against Malaria: Synthesis and in silico Molecular Docking Studies
The research explores the synthesis of a series of novel hybrid quinazolin-2,4-dione analogues bearing acetyl/amide bridged-Nitrogen heterocyclic moieties such as …
Article scientifique
New Perspectives on Plant Adenylyl Cyclases
It is increasingly clear that plant genomes encode numerous complex multi-domain proteins that harbour functional adenylyl cyclase (AC) centres. These …
Article scientifique
Applying Machine Learning of Erythrocytes Dynamic Antigens Store in Medicine
Erythrocytes Dynamic Antigens Store (EDAS) is a new discovery. EDAS consists of self-antigens and foreign (non-self) antigens. In patients with …
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