152 publication(s) trouvée(s)
Article scientifique
Risk factors profile and outcomes of stroke in low resources settings: a prospective and multicentric study in a sub-Saharan Africa country
Introduction Stroke is a leading cause of mortality and disability worldwide, with a disproportionate burden in low- and middle-income countries. …
Article scientifique
Clinical phenotypes of motor neurone disease in a Kenyan hospital-based population
Background Motor neurone disease (MND) presentation is globally heterogenous and data on the clinical phenotype in Sub-Saharan Africa (SSA) is …
Article scientifique
Breaking the learned helplessness paradigm in chronic stroke: an intensive neuroplasticity framework bridging European technology and African innovation
Introduction: Most chronic stroke survivors develop learned helplessness regarding motor recovery prospects, accepting permanent disability despite evidence that neuroplasticity windows …
Article scientifique
Iron chelation as a therapeutic target in vanadium neurotoxicity and Parkinson's disease: role of medicinal plants
Bioprospecting plant natural products has yielded significant success in the development of symptomatic treatment of neurodegenerative diseases, including the two …
Article scientifique
Efficacy and safety of edaravone dexborneol in acute ischemic stroke: systematic review and meta-analysis
Background Edaravone dexborneol represents a novel neuroprotective agent utilized in the treatment of acute ischemic stroke (AIS). Preliminary studies indicate …
Article scientifique
Frequency and risk factors of sleep problems in Egyptian patients with multiple sclerosis
Background: Sleep problems impact over 65% of patients with multiple sclerosis (MS), a prevalence significantly greater than that observed in …
Article scientifique
Cerebrolysin as an adjuvant therapy after mechanical thrombectomy in large vessel occlusion cardioembolic stroke: a propensity score matching analysis
Introduction Endovascular recanalization therapy has demonstrated considerable efficacy in the treatment of acute ischemic stroke (AIS). However, not all patients …
Article scientifique
Determinants of epilepsy among outpatients in public health institutions of Dawo district, South West Shoa Zone, Oromia, Ethiopia, 2023: an institutional-based unmatched case-control study
Background Globally, in ~50% of epilepsy cases, the underlying cause remains unknown, despite the fact that various disease pathways may …
Article scientifique
Changes in serum concentration of perioperative inflammatory cytokines following the timing of surgery among mild–moderate traumatic brain injury patients and factors associated
Background The safe timing window for surgery during the acute phase of inflammation due to traumatic brain injury (TBI) has …
Article scientifique
Variability of day-to-day pulsatility index change in children with cerebral malaria
Introduction: Cerebral malaria (CM) is a devastating disease and better understanding of etiologies of the resulting neurologic injury is needed. …
Article scientifique
Predictive model for aminoglycoside induced ototoxicity
Background: Irreversible hearing loss is a well-known adverse effect of aminoglycosides, however, inability to accurately predict ototoxicity is a major …
Article scientifique
Mortality and its predictors among patients with Guillain–Barré syndrome in the intensive care unit of a low-income country, Ethiopia: a multicenter retrospective cohort study
Background Guillain–Barré syndrome (GBS) is a rare autoimmune disease that affects the peripheral nervous system. It is characterized by the …
Article scientifique
Genetic profile of progressive myoclonic epilepsy in Mali reveals novel findings
Background and objectives Progressive myoclonic epilepsy (PME) is a group of neurological disorders characterized by recurrent myoclonic seizures with progressive …
Article scientifique
Incidence, risk factors and outcomes of traumatic head injury among trauma patients visited at the Yanet Trauma and Surgery Specialized Centre, Sidama region, Hawassa, Ethiopia: cohort study
Introduction: Traumatic brain injuries are a major public health concern that contributes to youth morbidity and mortality in developing nations, …
Article scientifique
Correlation of silent brain infarcts and leukoaraiosis in middle-aged ischemic stroke patients: a retrospective study
Background: Cerebrovascular diseases of the brain are usually defined by transient ischemic attacks and strokes. However, they can also cause …
Article scientifique
Anti-seizure medication prescription preferences: a Moroccan multicenter study
Background The management of epilepsy is mainly based on antiseizure medications (ASMs). More than 20 ASMs have been introduced in …
Article scientifique
Incidence and etiology of traumatic spinal cord injury in Rwanda: a prospective population-based study
Background Traumatic spinal cord injury (TSCI) is not only a life-threatening but also life changing event that happens suddenly, the …
Article scientifique
Advancing understanding of the role of IL-22 in myelination: insights from the Cuprizone mouse model
Despite significant advancements in the field, the pathophysiology of multiple sclerosis (MS) remains partially understood, with limited therapeutic options available …
Article scientifique
Daily management of gliomas, glioneuronal, and neuronal tumors in the era of the 2021 WHO classification of nervous tumors
updates to better classify CNS tumors taking into account the rapid advance of knowledge. Indeed, limits had quickly appeared in …
Article scientifique
Re-telling the story of aminoglycoside ototoxicity: tales from sub-Saharan Africa
Background: Aminoglycosides, such as Streptomycin, are cheap, potent antibiotics widely used Sub-Saharan Africa. However, aminoglycosides are the commonest cause of …