220 publication(s) trouvée(s)
Éditorial
Editorial: Management of Immune-Related Adverse Events for Patients Undergoing Treatment With Checkpoint Inhibitors
Treatment With Checkpoint InhibitorsImmunotherapy with immune checkpoint inhibitors has emerged as the most significant advance in the treatment of cancer …
Article scientifique
Survivin in Insulin-Like Growth Factor-Induced Resistance to Lapatinib in Head and Neck Squamous Carcinoma Cells
Epidermal growth factor receptor (EGFR) inhibitors have limited efficacy in head and neck squamous cell carcinoma (HNSCC) due to various …
Article scientifique
The Expression Patterns of FAM83H and PANX2 Are Associated With Shorter Survival of Clear Cell Renal Cell Carcinoma Patients
FAM83H is primarily known for its role in amelogenesis; however, recent reports suggest FAM83H might be involved in tumorigenesis. Although …
Article scientifique
A Pharmacogenetic Study of VDR fok1 and TYMS Polymorphisms and Their Association With Glucocorticoid-Induced Osteonecrosis in Egyptian Children With Acute Lymphoblastic Leukemia
Purpose: Osteonecrosis is a significant toxicity resulting from the treatment of pediatric Acute Lymphoblastic Leukemia. This study aimed to investigate …
Article scientifique
Evaluation of Knowledge, Perception, and Risk Awareness About Breast Cancer and Its Treatment Outcome Among University of Gondar Students, Northwest Ethiopia
Background: Breast cancer is among the most common life-threatening public health problems of global concern including Ethiopia. Knowledge and awareness …
Article scientifique
Defective Nuclear Lamina in Aneuploidy and Carcinogenesis
Aneuploidy, loss or gain of whole chromosomes, is a prominent feature of carcinomas, and is generally considered to play an …
Article scientifique
Neoadjuvant vs. Adjuvant Chemotherapy in Muscle Invasive Bladder Cancer (MIBC): Analysis From the RISC Database
Background: MIBC is an aggressive disease, with 5-year survival rates ranging from 36% to 48% for p T3/p T4/p N+tumors. …
Article scientifique
SIRT6 Is Involved in the Progression of Ovarian Carcinomas via β-Catenin-Mediated Epithelial to Mesenchymal Transition
SIRT6 is involved in various cellular signaling pathways including those involved in tumorigenesis in association with β-catenin. However, the role …
Article scientifique
EBV Associated Breast Cancer Whole Methylome Analysis Reveals Viral and Developmental Enriched Pathways
Background Breast cancer (BC) ranks among the most common cancers in Sudan and worldwide with hefty toll on female health …
Article scientifique
Machine Learning Applications in Head and Neck Radiation Oncology: Lessons From Open-Source Radiomics Challenges
Radiomics leverages existing image datasets to provide non-visible data extraction via image post-processing, with the aim of identifying prognostic and …
Article scientifique
Organ-Specific Toxicities Due to Radiation Therapy in Cancer Patients With or Without HIV Infection: A Systematic Review of the Literature
BACKGROUND: To synthesize published literature on the association between human immunodeficiency virus (HIV) infection and radiation therapy (RT)-related toxicities. METHODS: …
Article scientifique
A Step Toward Timely Referral and Early Diagnosis of Cancer: Implementation and Impact on Knowledge of a Primary Care-Based Training Program in Botswana
INTRODUCTION: Health system delays in diagnosis of cancer contribute to the glaring disparities in cancer mortality between high-income countries and …
Article scientifique
Local and Regional Breast Cancer Recurrences: Salvage Therapy Options in the New Era of Molecular Subtypes
Isolated local or regional recurrence of breast cancer (BC) leads to an increased risk of metastases and decreased survival. Ipsilateral …
Article scientifique
Planning Today for Tomorrow’s Research: Analysis of Factors Influencing Participation in a Pediatric Cancer Research Biorepository
Background: Biobanks have become a powerful tool that fosters biomedical research. The success of biobanks depends upon people’s perception and …
Article scientifique
Domesticating Cancer: An Evolutionary Strategy in the War on Cancer
Since cancer shares the same molecular machinery as the host, most therapeutic interventions which aim to target cancer would inadvertently …
Article scientifique
Delineation of the HPV11E6 and HPV18E6 Pathways in Initiating Cellular Transformation
Although high-risk human papillomaviruses (HPVs) are the major risk factors for cervical cancer they have been associated with several other …
Article scientifique
Cancers Attributable to Alcohol Consumption in Nigeria: 2012–2014
INTRODUCTION: Alcohol consumption has been identified as a risk factor for many cancers but less attention has been paid to …
Article scientifique
Investigation of Metastasis-Related Genes: A Rat Model Mimicking Liver Metastasis of Colorectal Carcinoma
Liver is the main target of colorectal cancer (CRC) metastasis. Currently, the number of reports is small, which describe changes …
Article scientifique
Genomic Signature of the Natural Oncolytic Herpes Simplex Virus HF10 and Its Therapeutic Role in Preclinical and Clinical Trials
Oncolytic viruses are opening new possibilities in cancer therapy with their unique mechanism of selective replication within tumor cells and …
Éditorial
Editorial: Aurora Kinases: Classical Mitotic Roles, Non-Canonical Functions and Translational Views
Aurora kinases are key mitotic regulators that have also been associated with tumor development and progression. The interest on this …
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