220 publication(s) trouvée(s)
Article scientifique
10-Year Mortality Pattern Among Cancer Patients in Lagos State University Teaching Hospital, Ikeja, Lagos
BACKGROUND: Globally, cancer is a major leading health problem with an estimated 10 million incidences and 6 million cancer deaths …
Article scientifique
Awareness of Cervical Cancer and Attitude Toward Human Papillomavirus and Its Vaccine Among Ghanaians
Background: Cervical cancer (CC) is the fourth most commonly diagnosed cancer among women. Ghana is a low-middle- income country with …
Éditorial
Commentary: SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
GENERAL COMMENTARY article Front. Oncol., 19 August 2020Sec. Molecular and Cellular Oncology Volume 10 - 2020 | https://doi.org/10.3389/fonc.2020.01448
Article scientifique
Efavirenz and Lopinavir/Ritonavir Alter Cell Cycle Regulation in Lung Cancer
Highly active anti-retroviral treatment (HAART) is currently the most effective treatment for HIV/AIDS. Additionally, HIV positive patients receiving HAART have …
Article scientifique
Association of the Trough, Peak/Trough Ratio of Imatinib, Pyridine–N-Oxide Imatinib and ABCG2 SNPs 34 G>A and SLCO1B3 334 T>G With Imatinib Response in Egyptian Chronic Myeloid Leukemia Patients
Imatinib mesylate (IM) is highly efficacious in the treatment of Chronic Myeloid Leukemia (CML). Therapeutic drug monitoring and pharmacogenetic screening …
Article scientifique
ULBP1 Is Elevated in Human Hepatocellular Carcinoma and Predicts Outcome
Hepatocellular carcinoma (HCC) remains a leading cause of cancer death worldwide, and despite recent immunotherapeutic advances there remains a need …
Article scientifique
Personalized Human Papillomavirus Vaccination for Persistence of Immunity for Cervical Cancer Prevention: A Critical Review With Experts' Opinions
The development of cervical cancer has been shown to involve both viral and host factors. The host factors are those …
Article scientifique
Amplification of 3q26.2, 5q14.3, 8q24.3, 8q22.3, and 14q32.33 Are Possible Common Genetic Alterations in Oral Cancer Patients
The lack of clinical biomarkers for head and neck cancer subtypes limits early diagnosis and monitoring of disease progression. This …
Article scientifique
Decreased Efficacy of Doxorubicin Corresponds With Modifications in Lipid Metabolism Markers and Fatty Acid Profiles in Breast Tumors From Obese vs. Lean Mice
Breast cancer cells modulate lipid and fatty acid metabolism to sustain proliferation. The role of adipocytes in cancer treatment efficacy …
Article scientifique
Potentiation of the Abscopal Effect by Modulated Electro-Hyperthermia in Locally Advanced Cervical Cancer Patients
Background: A Phase III randomized controlled trial investigating the addition of modulated electro-hyperthermia (mEHT) to chemoradiotherapy for locally advanced cervical …
Article scientifique
Insights About Circadian Clock and Molecular Pathogenesis in Gliomas
The circadian clock is an endogenous time-keeping system that has been discovered across kingdoms of life. It controls and coordinates …
Article scientifique
XIST and TSIX: Novel Cancer Immune Biomarkers in PD-L1-Overexpressing Breast Cancer Patients
Escaping antitumor immunity is a hallmark in cancer progression. Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor …
Article scientifique
Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
Triple-negative breast cancer (TNBC) accounts for ~15-20% of breast cancer (BC) and has a higher rate of early relapse and …
Article scientifique
Selective Regulation of B-Raf Dependent K-Ras/Mitogen-Activated Protein by Natural Occurring Multi-kinase Inhibitors in Cancer Cells
Introduction: Cancer is one of the most difficult challenges faced by humanity due to its many associated issues, such as …
Article scientifique
Review of the Clinical Evidences of Modulated Electro-Hyperthermia (mEHT) Method: An Update for the Practicing Oncologist
Background: Modulated electro-hyperthermia (mEHT) is a variation of the conventional hyperthermia which selectively targets the malignant cell membranes in order …
Article scientifique
Globular C1q Receptor (gC1qR/p32/HABP1) Is Overexpressed in Malignant Pleural Mesothelioma and Is Associated With Increased Survival in Surgical Patients Treated With Chemotherapy
Introduction: Globular C1q receptor (gC1qR/p32/HABP1) is overexpressed in a variety of cancers, particularly adenocarcinomas. This study investigated gC1qR expression in …
Article scientifique
KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma
In multiple myeloma the mutational profile is mainly represented by translocations involving chromosome 14 and by single nucleotide mutations, frequently …
Article scientifique
Gene Expression Profiling Analysis Reveals Putative Phytochemotherapeutic Target for Castration-Resistant Prostate Cancer
Prostate cancer is the leading cause of cancer death among men globally, with castration development resistant contributing significantly to treatment …
Article scientifique
Tuberculosis Infection in a Patient Treated With Nivolumab for Non-small Cell Lung Cancer: Case Report and Literature Review
Nivolumab (PD-1 blocker) and other immune checkpoint inhibitors are used primarily to promote reactivation of anti-tumor immunity. However, due to …
Article scientifique
Cancers Attributable to Overweight and Obesity From 2012 to 2014 in Nigeria: A Population-Based Cancer Registry Study
Background: Overweight and obesity are known risk factors for chronic diseases including cancers. In this study, we evaluated the age …