220 publication(s) trouvée(s)
Article scientifique
Risk factors of oesophageal cancer at health facilities in Addis Ababa, Ethiopia: Unmatched case control study
Background: Oesophageal carcinoma is one of the most common cancers in Ethiopia. Its occurrences vary among regional states of the …
Article scientifique
Inflammatory Breast Cancer: The Secretome of HCMV+ Tumor-Associated Macrophages Enhances Proliferation, Invasion, Colony Formation, and Expression of Cancer Stem Cell Markers
Inflammatory breast cancer (IBC) is a highly aggressive phenotype of breast cancer that is characterized by a high incidence early …
Article scientifique
The Role and Interactions of Programmed Cell Death 4 and its Regulation by microRNA in Transformed Cells of the Gastrointestinal Tract
Data from GLOBOCAN 2020 estimates that there were 19.3 million new cases of cancer and 10.0 million cancer-related deaths in …
Article scientifique
Role of Adenoviruses in Cancer Therapy
Cancer is one of the leading causes of death in the world, which is the second after heart diseases. Adenoviruses …
Article scientifique
Prospective Medicinal Plants and Their Phytochemicals Shielding Autoimmune and Cancer Patients Against the SARS-CoV-2 Pandemic: A Special Focus on Matcha
Background: Being "positive" has been one of the most frustrating words anyone could hear since the end of 2019. This …
Article scientifique
Peripheral Organ Equivalent Dose Estimation Procedure in Proton Therapy
The aim of this work is to present a reproducible methodology for the evaluation of total equivalent doses in organs …
Article scientifique
RNA Therapeutic Options to Manage Aberrant Signaling Pathways in Hepatocellular Carcinoma: Dream or Reality?
Despite the early promise of RNA therapeutics as a magic bullet to modulate aberrant signaling in cancer, this field remains …
Article scientifique
Hyperthermic Intraperitoneal Chemotherapy and Cytoreductive Surgery in Ovarian Cancer: An Umbrella Review of Meta-Analyses
Background: The utility of heated intraperitoneal chemotherapy (HIPEC) in the management of epithelial ovarian cancer (EOC) has been assessed in …
Article scientifique
Glioblastoma Following Treated Medulloblastoma After 29 Years in the Posterior Fossa: Case Report and Review of Literature
Glioblastoma multiforme (GBM) is a high-grade glioma that may be a rare complication of radiotherapy. We report a case of …
Article scientifique
The African Female Breast Cancer Epidemiology Study Protocol
Breast cancer is now the commonest cancer in most sub-Saharan African countries. Few studies of the epidemiology and genomics of …
Article scientifique
Leukemia Stem Cell Frequency at Diagnosis Correlates With Measurable/Minimal Residual Disease and Impacts Survival in Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a heterogenous disease in which the initiation and maintenance of the malignant clone is blamed …
Article scientifique
Anticancer Properties of Curcumin Against Colorectal Cancer: A Review
Colorectal cancer (CRC) is one of the most common and reoccurring diseases, as well as the world’s second largest cause …
Article scientifique
Effects of Metformin Combined With Antifolates on HepG2 Cell Metabolism and Cellular Proliferation
Hepatocellular carcinoma (HCC), one of the most prevalent types of cancers worldwide, continues to maintain high levels of resistance to …
Article scientifique
Elevated Levels of Soluble CTLA-4, PD-1, PD-L1, LAG-3 and TIM-3 and Systemic Inflammatory Stress as Potential Contributors to Immune Suppression and Generalized Tumorigenesis in a Cohort of South African Xeroderma Pigmentosum Patients
Xeroderma Pigmentosum (XP), an autosomal recessive disorder characterized by ultraviolet radiation-induced abnormalities of DNA excision and repair pathways is associated …
Article scientifique
Immune Checkpoint and Telomerase Crosstalk Is Mediated by miRNA-138 in Bladder Cancer
BACKGROUND: Tumor recurrence and progression in non-muscle invasive bladder cancer (NMIBC), therapy failure, and severe side effects in muscle invasive …
Article scientifique
New Insights Into c.815_824dup Pathogenic Variant of BRCA1 in Inherited Breast Cancer: A Founder Mutation of West African Origin
Founder mutations have been reported inBRCA1andBCRA2in different ethnic groups with inherited breast cancer. Testing of targeted mutations in specific populations …
Article scientifique
The Role of MRI Pancreatic Protocol in Assessing Response to Neoadjuvant Therapy for Patients With Borderline Resectable Pancreatic Cancer
Background Borderline Resectable Pancreatic Cancer (BRPC) remains a unique entity that is difficult to categorize due to variance in definitions …
Article scientifique
Pretherapeutic Assessment of Pancreatic Cancer: Comparison of FDG PET/CT Plus Delayed PET/MR and Contrast-Enhanced CT/MR
Purpose This study aims to determine the diagnostic performance of whole-body FDG PET/CT plus delayed abdomen PET/MR imaging in the …
Article scientifique
Plasma EBV DNA: A Promising Diagnostic Marker for Endemic Burkitt Lymphoma
Endemic Burkitt lymphoma (eBL) is the most common childhood cancer in regions of equatorial Africa where P. falciparum malaria is …
Article scientifique
EGFR-Dependent Extracellular Matrix Protein Interactions Might Light a Candle in Cell Behavior of Non-Small Cell Lung Cancer
Lung cancer remains the leading cause of cancer-related death and is associated with a poor prognosis. Lung cancer is divided …