486 publication(s) trouvée(s)
Article scientifique
Vitamin D3 alleviates nonalcoholic fatty liver disease in rats by inhibiting hepatic oxidative stress and inflammation via the SREBP-1-c/ PPARα-NF-κB/IR-S2 signaling pathway
Introduction: Nonalcoholic fatty liver disease (NAFLD) is a chronic disease characterized by fat deposits in liver cells, which can lead …
Éditorial
Editorial: Natural products as potential therapies for non-alcoholic fatty liver disease
Editorial on the Research Topic Natural products as potential therapies for non-alcoholic fatty liver disease Non-alcoholic fatty liver disease (NAFLD) …
Éditorial
Editorial: Novel antimicrobials and antibiotics resistance modulating agents from natural products: Turning promises into Triumphs
Editorial on the Research Topic Novel antimicrobials and antibiotics resistance modulating agents from natural products: Turning promises into Triumphs With …
Article scientifique
Preeclamptic programming unevenly perturbs inflammatory and renal vasodilatory outcomes of endotoxemia in rat offspring: modulation by losartan and pioglitazone
Introduction: Preeclampsia (PE) enhances the vulnerability of adult offspring to serious illnesses. The current study investigated whether preeclamptic fetal programming …
Article scientifique
Ethnobotanical uses, phytochemistry and biological activity of the genus Euclea: A review
Euclea (Ebenaceae) is a genus of flowering shrubs and trees widely distributed in Africa, the Comoro Islands, and Arabia. This …
Article scientifique
Evaluating the safety and efficacy of the leukotriene receptor antagonist montelukast as adjuvant therapy in obese patients with type 2 diabetes mellitus: A double-blind, randomized, placebo-controlled trial
Background: Type 2 diabetes mellitus (T2DM) is common with obesity. Metformin is a first-line therapy for this condition. However, it …
Article scientifique
Tanacetum species: Bridging empirical knowledge, phytochemistry, nutritional value, health benefits and clinical evidence
Introduction: The Tanacetum genus consists of 160 accepted flowering species thriving throughout temperate regions, mainly in the Mediterranean Basin, Northern …
Article scientifique
An overview of natural products that modulate the expression of non-coding RNAs involved in oxidative stress and inflammation-associated disorders
Oxidative stress is a state in which oxidants are produced in excess in the body’s tissues and cells, resulting in …
Article scientifique
Optimisation of alpha-amylase inhibitor production in solid state fermentation
Though not a known producer of alpha-amylase inhibitor, the potential of Streptomyces xinghaiensis AAI-2 to produce this important metabolite was …
Article scientifique
Cyclopia extracts act as selective estrogen receptor subtype downregulators in estrogen receptor positive breast cancer cell lines: Comparison to standard of care breast cancer endocrine therapies and a selective estrogen receptor agonist and antagonist
Breast cancer is the most diagnosed type of cancer amongst women in economically developing countries and globally. Most breast cancers …
Article scientifique
Cognitive- and memory-enhancing effects of Augmentin in Alzheimer’s rats through regulation of gene expression and neuronal cell apoptosis
Introduction: Alzheimer’s disease (AD) is the most common type of dementia among older persons. This study looked at how Augmentin …
Article scientifique
The effect of high oral loading dose of cholecalciferol in non-alcoholic fatty liver disease patients. A randomized placebo controlled trial
Background and Aim: Non-alcoholic fatty liver (NAFLD) is one of the most common progressive metabolic disorders worldwide. There are increasing …
Article scientifique
Smallholders’ knowledge about healing goat gastrointestinal parasite infections with wild plants in southern DR Congo
Gastrointestinal parasite (GIP) infections control has an important role to play in increasing livestock production from a limited natural resource …
Article scientifique
Dimethyl fumarate abrogates striatal endoplasmic reticulum stress in experimentally induced late-stage Huntington’s disease: Focus on the IRE1α/JNK and PERK/CHOP trajectories
Introduction: Dimethyl fumarate (DMF) is FDA-approved for use in patients with relapsing multiple sclerosis, and it processes neuroprotection in several …
Article scientifique
Efficacy and safety of praziquantel preventive chemotherapy in Schistosoma mansoni infected school children in Southern Ethiopia: A prospective cohort study
Background: The World Health Organization recommends efficacy and safety surveillance of anti-helminths used in mass drug administration campaigns. We evaluated …
Article scientifique
Pomegranate peel extract protects against the development of diabetic cardiomyopathy in rats by inhibiting pyroptosis and downregulating LncRNA-MALAT1
Background:Pyroptosis is an inflammatory programmed cell death accompanied by activation of inflammasomes and maturation of pro-inflammatory cytokines interleukin-1β (IL-1β) and …
Article scientifique
Real-world disparities and ethical considerations with access to CFTR modulator drugs: Mind the gap!
The third Sustainable Development Goal (SDG), to ensure healthy lives and promote well-being for all at all ages, has particular …
Article scientifique
UHPLC-MS profiles and antidiarrheal activity of Quercus coccinea münchh. and Quercus robur L. employing in vivo technique
Introduction:Quercus L. genus (Oak) belongs to the family Fagaceae and their galls are used commercially in leather tanning, dyeing, and …
Article scientifique
The use of African medicinal plants in cancer management
Cancer is the third leading cause of premature death in sub-Saharan Africa. Cervical cancer has the highest number of incidences …
Article scientifique
Clofazimine for the treatment of tuberculosis
Shorter (6–9 months), fully oral regimens containing new and repurposed drugs are now the first-choice option for the treatment of …