486 publication(s) trouvée(s)
Article scientifique
Curcumin and cinnamon mitigates lead acetate-induced oxidative damage in the spleen of rats
Lead toxicity is a common occupational and environmental health hazard that exerts many toxic effects on animals and humans, including …
Article scientifique
Targeted ferroptotic potency of ferrous oxide nanoparticles-diethyldithiocarbamate nanocomplex on the metastatic liver cancer
Existing treatments are frequently ineffective in combating liver cancer (LC) due to its rapid growth, high metastatic potential, and chemoresistance. …
Article scientifique
Uterine fibroids — Causes, impact, treatment, and lens to the African perspective
Leiomyomas, or uterine fibroids as they are commonly known, are mostly seen in women of reproductive age. However, they can …
Article scientifique
Assessment of toxicity and anti-plasmodial activities of chloroform fractions of Carapa procera and Alchornea cordifolia in murine models
Background:Plant as a source of medicine has gained international popularity in recent times because of its natural origin, availability in …
Article scientifique
Efficacy and safety profile of corticosteroids and non-steroidal anti-inflammatory drugs in COVID-19 management: A narrative review
Due to the fact that coronavirus disease 2019 (COVID-19) is still prevalent, and current reports show that some parts of …
Article scientifique
Comprehensive assessment on the applications of oncolytic viruses for cancer immunotherapy
The worldwide burden of cancers is increasing at a very high rate, including the aggressive and resistant forms of cancers. …
Éditorial
Editorial: Women in drugs outcomes research and policies: 2021
Editorial on the Research Topic Women in drugs outcomes research and policiesScience and gender equality are essential to ensure sustainable …
Article scientifique
Nanodelivery of antiretroviral drugs to nervous tissues
Despite the development of effective combined antiretroviral therapy (cART), the neurocognitive impairments associated with human immunodeficiency virus (HIV) remain challenging. …
Article scientifique
Institutionalizing health technology assessment in Egypt: Situational analysis and roadmap
Objective: To conduct a situational analysis with the aim to inform future health technology assessment efforts (HTA) in Egypt. Introduction: …
Article scientifique
Ethnobotanical study of endemic and non-endemic medicinal plants used by indigenous people in environs of Gullele botanical garden Addis Ababa, central Ethiopia: A major focus on Asteraceae family
Gullele Botanical Garden (GBG) in Addis Ababa, Ethiopia is a joint venture of Addis Ababa government and the university. The …
Éditorial
Editorial: Pharmacometrics—tools to assure optimal medicine use in low- and middle-income countries
pharmacometrics, low-and lower-middle-income countries, pharmacokinetic/ pharmacodynamic (PK/PD), optimized dosage, communicable and noncommunicable diseases Editorial on the Research Topic Pharmacometrics-tools to …
Article scientifique
The novel anti-colitic effect of β-adrenergic receptors via modulation of PS1/BACE-1/Aβ axis and NOTCH signaling in an ulcerative colitis model
Although dysautonomia was documented in inflammatory bowel disease, with activation of the stress-related sympathetic system, the role of agonists/antagonists of …
Article scientifique
Extract of Mallotus oppositifolius (Geiseler) Müll. Arg. increased prefrontal cortex dendritic spine density and serotonin and attenuated para-chlorophenylalanine-aggravated aggressive and depressive behaviors in mice
Background/Aim:Depression-related aggression is linked to serotonin (5-HT) and dendritic spine alterations. AlthoughMallotus oppositifoliusextract (MOE) has potential for reducing this effect, …
Article scientifique
Selenium-enriched yeast modulates the metal bioaccumulation, oxidant status, and inflammation in copper-stressed broiler chickens
Copper (Cu) could be seriously hazardous when present at excessive levels, despite its vital contribution to various cellular processes. Selenium-enriched …
Article scientifique
Aqueous extract of Parkia biglobosa (Jacq.) R. Br. (Fabaceae) exerts antiepileptogenic, anti-amnesic, and anxiolytic-like effects in mice via mechanisms involving antioxidant and anti-inflammatory pathways
Parkia biglobosa (Jacq.) R. Br. (Fabaceae) is a widely distributed tree, used in traditional medicine to treat amebiasis, hookworm infection, …
Article scientifique
Antioxidant-based neuroprotective effect of dimethylsulfoxide against induced traumatic brain injury in a rats model
Traumatic brain injury (TBI) has been the result of neurological deficit and oxidative stress. This study evaluated the antioxidative neuroprotective …
Article scientifique
In vitro α-amylase and hemoglobin glycation inhibitory potential of Nigella sativa essential oil, and molecular docking studies of its principal components
Nigella sativa is plant that is endowed with various pharmacological activities including antioxidant, anticancer, anti-inflammatory, antibacterial, antidiabetic, and immunostimulant. This …
Article scientifique
Synergistic antioxidant effects of natural compounds on H2O2-induced cytotoxicity of human monocytes
Natural compounds are endowed with a broad spectrum of biological activities, including protection against Toxins. Most of them are known …
Article scientifique
Characterization of resistant MCF-7 breast cancer cells developed by repeated cycles of photodynamic therapy
Breast cancer mainly affects women and causes a severe global threat to health. It is often managed and treated with …
Article scientifique
Tetraclinis articulata (vahl) masters: An insight into its ethnobotany, phytochemistry, toxicity, biocide and therapeutic merits
Tetraclinis articulata(Vahl) Masters, commonly known as Sandarac tree and Araâr, is the only species representing the genusTetraclinisMasters. The plant has …