30 publication(s) trouvée(s)
Article scientifique
Prevalence of pre-diabetes, newly diagnosed diabetes, and associated COVID-19 disease severity in patients hospitalized at Sir Ketumile Masire Teaching Hospital, Botswana
Background The mechanism of diabetes with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and onset in COVID-19 patients remains unclear. We …
Article scientifique
Dolutegravir-based antiretroviral therapy-associated hyperglycemia in persons living with human immunodeficiency virus in Niger: a multicentric cross-sectional study
Background Growing evidence from clinical and experimental research suggests that dolutegravir is associated with hyperglycemia. This study aimed to determine …
Article scientifique
Exploring the role of rotavirus, adenovirus, and norovirus in gastroenteritis among children in Iraq: an epidemiological and molecular study
Background and aim Acute gastroenteritis (AGE) is a major cause of morbidity and mortality among children <5 years, with rotavirus …
Article scientifique
Molecular systems of emerging viruses: replication, host immune evasion, cross-species adaptation and precision countermeasures
Emerging and re-emerging viruses are difficult to anticipate because epidemic potential emerges from interacting molecular, ecological and social processes. This …
Article scientifique
Editorial: Epidemiology and control of blood-borne viruses in low- and middle-income countries: genomic insights and public health strategies
Blood-borne viruses (BBVs), including human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and human T-cell lymphotropic …
Article scientifique
Current trends in the epidemiology and management of viral co-infections and comorbidities in Africa: a systematic review
Background Viral infections, particularly hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis Delta virus (HDV), and human immunodeficiency virus …
Article scientifique
Case report: Kinetics of viral load, immunoglobulins, and cytokines in a fatal case of Crimean-Congo hemorrhagic fever virus
A fatal case of Crimean-Congo hemorrhagic fever virus (CCHFV) was detected in Dakar, Senegal, West Africa, in April 2023. To …
Article scientifique
Potential mechanisms underlying bluetongue virus emergence and spread
Bluetongue is a non-zoonotic arboviral disease transmitted by biting midges of the genus Culicoides. Among 1,347 Culicoides species, 30 are …
Article scientifique
Seroprevalence of anti-SARS-CoV-2 IgM and IgG and COVID-19 vaccine uptake in healthy volunteers in Nairobi, Kenya: a cross-sectional study
Introduction Seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) antibodies in the postvaccination period in Kenya remains to be …
Article scientifique
Human cellular restriction factors that target SARS-CoV-2 replication
Millions of people have died and a worldwide economic catastrophe has been brought on by the coronavirus disease 2019 (COVID-19) …
Article scientifique
Editorial: Interaction between virus and host cell: how do viruses cause cellular dysregulation?
Viruses are opportunistic pathogens that hijack host cell machinery including control of host cell cycle, apoptosis, immunity and essential cellular …
Article scientifique
Seroprevalence of dengue, yellow fever, and related flaviviruses among the rural human population in Nguruman and Kerio Valley, Kenya
Background: Yellow fever virus (YFV) and dengue virus (DENV) are among the major re-emerging arboviruses that pose a significant threat …
Article scientifique
Editorial: Characterization of HIV-1 variants: implications for HIV-1 prevention, treatment and cure
HIV-1M subtypes have uneven spread and prevalence [2]. Previous work indicates that subtypespecific variation in the fitness of isolates or …
Article scientifique
Severe acute respiratory syndrome coronavirus-2 seroprevalence in non-vaccinated people living with HIV in Uganda during 2022
A cross-sectional study on severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) seroprevalence among unvaccinated people living with HIV (PLWH) was conducted …
Article scientifique
HIV latency potential may be influenced by intra-subtype genetic differences in the viral long-terminal repeat
Introduction Elucidation of mechanisms that drive HIV latency is essential to identifying cure strategies. While host mechanisms associated with viral …
Article scientifique
No detectable differences in Nef-mediated downregulation of HLA-I and CD4 molecules among HIV-1 group M lineages circulating in Cameroon, where the pandemic originated
HIV-1 group M (HIV-1M) lineages downregulate HLA-I and CD4 expression via their Nef proteins. We hypothesized that these Nef functions …
Article scientifique
Isolation and phylogenetic characterization of arboviruses circulating among phlebotomine sandflies in parts of North Rift, Kenya
Background Until recently, arbovirus surveillance is mainly focused on mosquito and tick vectors, resulting in the discovery of several mosquito- …
Article scientifique
Beyond survival: unraveling the dynamics of Ebola virus resurgence in Sub-Saharan Africa and the remarkable journey of survivors
Ebola virus disease (EVD) remains a significant public health threat, with sporadic outbreaks occurring in Sub-Saharan Africa. Survivors of EVD …
Article scientifique
Clinical spectrum of COVID-19 at a national referral hospital in western Kenya during the period 2020–2021
Introduction We describe the clinical spectrum of COVID-19 cases in western Kenya from 6 April 2020 to 31 May 2021, …
Article scientifique
Prediction and surveillance of de novo HCC in patients with compensated advanced chronic liver disease after hepatitis C virus eradication with direct antiviral agents
The risk of hepatocellular carcinoma (HCC) diminishes in patients with hepatitis C virus (HCV)-related advanced chronic liver disease after virological …
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