43 publication(s) trouvée(s)
Article scientifique
Microbiome/transforming growth factor-β axis as a diagnostic and therapeutic target for MASLD in Egyptian patients
Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the leading cause of chronic hepatic disorders worldwide. Gut microbiome dysbiosis …
Article scientifique
Serial serum interleukin-8 trajectories are associated with progression from Helicobacter pylori–associated precancerous lesions to gastric cancer: a prospective longitudinal cohort study
BACKGROUND: Gastric cancer remains the fourth leading cause of cancer-related mortality worldwide, with delayed diagnosis contributing to poor prognosis. Current …
Article scientifique
Synergistic potentiation of antibiotics by chamomile phytochemicals against multidrug-resistant Helicobacter pylori
BACKGROUND: Helicobacter pylori is a significant global health issue, infecting nearly half of the population. Increasing antibiotic resistance leads to …
Article scientifique
Effect of Moringa oleifera and ivermectin nanoparticles on the immunopathological response during experimental trichinosis in mice
Trichinella spiralis (T. spiralis) infection dynamically modulates macrophage polarization. It promotes M1 macrophage polarization, enhancing the pro-inflammatory pathways. This study …
Article scientifique
Gut microbiome dysbiosis in hepatocellular carcinoma patients with persistent HCV viremia versus viral clearance: a cross-sectional study
BACKGROUND: Hepatocellular carcinoma (HCC) remains a lethal complication of chronic hepatitis C virus (HCV) infection, even after successful direct-acting antiviral …
Article scientifique
Assessment of immunological and hematological parameters in Blastocystis species-infected chronic leukemic patients
AIM: Blastocystis spp. is a common intestinal protozoan with controversial pathogenicity. It is frequently associated with gastrointestinal (GIT) disturbances and …
Article scientifique
Recent insights on challenges encountered with phage therapy against gastrointestinal-associated infections
Gastrointestinal (GI) infections, caused by pathogens such as Escherichia coli, Salmonella sp., Shigella sp., and Clostridium difficile, pose significant global …
Article scientifique
Gut microbiome and gastric cancer: microbial interactions and therapeutic potential
The development of gastric cancer is significantly influenced by the intestinal microbiota, with H. pylori serving as a major risk …
Article scientifique
Chicken as a carrier of emerging virulent Helicobacter species: a potential zoonotic risk
BACKGROUND: The research scope regarding Helicobacter species in chickens, other than H. pullorum, is largely overlooked. This study aimed to …
Article scientifique
Transmission pathways of Campylobacter jejuni between humans and livestock in rural Ethiopia are highly complex and interdependent
BACKGROUND: Campylobacter jejuni and C. coli are the most common causes of bacterial enteritis worldwide whereas symptomatic and asymptomatic infections …
Article scientifique
Sero—salivary detection of H. pylori immunoglobulins and parasitic infection among healthcare individuals suffering from gastrointestinal disorders with correlation to personal hygiene
BACKGROUND: Gastrointestinal microbial infections among healthcare individuals (HCIs) are common due to several risk factors, including poor personal hygiene and …
Article scientifique
Enterococcus and Eggerthella species are enriched in the gut microbiomes of COVID-19 cases in Uganda
BACKGROUND: Infection with the COVID-19-causing pathogen SARS-CoV-2 is associated with disruption in the human gut microbiome. The gut microbiome enables …
Article scientifique
Long-read 16S rRNA amplicon sequencing reveals microbial characteristics in patients with colorectal adenomas and carcinoma lesions in Egypt
BACKGROUND: Colorectal cancer (CRC) is among the five leading causes of cancer incidence and mortality. During the past decade, the …
Article scientifique
Gut microbiota dysbiosis and associated immune response in systemic lupus erythematosus: impact of disease and treatment
BACKGROUND: Gut microbial dysbiosis and leaky gut play a role in systemic lupus erythematosus (SLE). Geographical location and dietary habits …
Article scientifique
Efficacy of colistin-based combinations against pandrug-resistant whole-genome-sequenced Klebsiella pneumoniae isolated from hospitalized patients in Egypt: an in vitro/vivo comparative study
Abstract Background Colistin resistance significantly constrains available treatment options and results in the emergence of pandrug-resistant (PDR) strains. Treating PDR …
Article scientifique
Molecular characterization and risk analysis of Giardia duodenalis assemblages in corticosteroid-treated and non-treated patients in Ismailia, Arab Republic of Egypt
BACKGROUND: Giardia duodenalis (G. duodenalis) is an intestinal protozoan parasite of human and animal hosts. The present study investigated and …
Article scientifique
Genomic characterisation of an extended-spectrum β-Lactamase-producing Klebsiella pneumoniae isolate assigned to a novel sequence type (6914)
BACKGROUND: Cow milk, which is sometimes consumed raw, hosts a plethora of microorganisms, some of which are beneficial, while others …
Article scientifique
Gastrointestinal parasitic infections: Prevalence and risk factors in West Ismailia, Arab Republic of Egypt
BACKGROUND: This study aimed to determine the prevalence of gastrointestinal parasites (GIP) in the rural community of West Ismailia and …
Article scientifique
Prevalence of Helicobacter pylori infection and effectiveness of first-line triple eradication therapy among dyspeptic patients at hospitals in Hawassa City, Ethiopia: a cross-sectional follow-up study
BACKGROUND: Dyspepsia is a common gastrointestinal illness sometimes associated with Helicobacter pylori (H. pylori) infection. Screening and eradicating the bacterium …
Article scientifique
Neutrophil percentage-to-albumin ratio is a new diagnostic marker for spontaneous bacterial peritonitis: a prospective multicenter study
BACKGROUND: The neutrophil percentage-to-albumin ratio (NPAR) is a novel measure of systemic inflammation and infection. Low albumin levels increase the …
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