12 publication(s) trouvée(s)
Article scientifique
Gonadal steroids as predictors of sex differences in tuberculosis outcomes
BACKGROUNDRecent evidence suggests a role for biological factors in increased risk for active pulmonary tuberculosis (PTB) among males. We determined …
Article scientifique
Population genomics of Plasmodium malariae from 4 African countries
BACKGROUNDMalaria caused by Plasmodium malariae is geographically widespread and sometimes associated with prolonged infection, yet little is known about its …
Article scientifique
HIV infection and ART exposure affect tumor TCR repertoire of diffuse large B cell lymphoma
The most common subtype of lymphoma globally, diffuse large B cell lymphoma (DLBCL), is a leading cause of cancer death …
Article scientifique
Strong off-target antibody reactivity to malarial antigens induced by RTS,S/AS01E vaccination is associated with protection
The RTS,S/AS01E vaccine targets the circumsporozoite protein (CSP) of the Plasmodium falciparum (P. falciparum) parasite. Protein microarrays were used to …
Article scientifique
Differential localization and limited cytotoxic potential of duodenal CD8+ T cells
The duodenum is a major site of HIV persistence during suppressive antiretroviral therapy despite harboring abundant tissue-resident memory (Trm) CD8+ …
Article scientifique
Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection
HIV infection in the human gastrointestinal (GI) tract is thought to be central to HIV progression, but knowledge of this …
Article scientifique
Determinants of brain swelling in pediatric and adult cerebral malaria
Cerebral malaria (CM) affects children and adults, but brain swelling is more severe in children. To investigate features associated with …
Article scientifique
HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells
SARS-CoV-2 infects epithelial cells of the human gastrointestinal (GI) tract and causes related symptoms. HIV infection impairs gut homeostasis and …
Article scientifique
Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss
The pathophysiology underlying spiral ganglion cell defect-induced deafness remains elusive. Using the whole exome sequencing approach, in combination with functional …
Article scientifique
Implicating bites from a leishmaniasis sand fly vector in the loss of tolerance in pemphigus
A possible etiological link between the onset of endemic pemphigus in Tunisia and bites of Phlebotomus papatasi, the vector of …
Article scientifique
IL-4Rα signaling in CD4+CD25+FoxP3+ T regulatory cells restrains airway inflammation via limiting local tissue IL-33
Impaired tolerance to innocuous particles during allergic asthma has been linked to increased plasticity of FoxP3+ regulatory T cells (Tregs) …
Article scientifique
Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site
Major advances in donor identification, antigen probe design, and experimental methods to clone pathogen-specific antibodies have led to an exponential …