221 publication(s) trouvée(s)
Article scientifique
A study on mutation points of GDF9 gene and their association with prolificacy in Egyptian small ruminants
BACKGROUND: Genetic variants of the GDF9 gene were considered to be the potent gene markers for improving fecundity traits in …
Article scientifique
Defining the molecular pathology and consequent phenotypes in Egyptian HB patients
BACKGROUND: Hemophilia B (HB) (also known as Christmas disease) is a rare X-linked recessive disorder characterized by spontaneous or prolonged …
Article scientifique
The immune response and protective efficacy of a potential DNA vaccine against virulent Pasteurella multocida
BACKGROUND: Pasteurella multocida is the main cause of several infections of farm animals, and the immunity gained from commercial vaccines …
Article scientifique
Genetic diversity and population structure of date palms (Phoenix dactylifera L.) in Ethiopia using microsatellite markers
BACKGROUND: Date palm tree (Phoenix dactylifera L.) is a perennial monocotyledonous plant belonging to the Arecaceae family, a special plant …
Article scientifique
Clinical impact of PTEN methylation status as a prognostic marker for breast cancer
BACKGROUND: Aberrant DNA methylation of phosphatase and tensin homolog (PTEN) gene has been found in many cancers. The object of …
Article scientifique
Chemical profiling, in vitro antimicrobial and antioxidant activities of pomegranate, orange and banana peel-extracts against pathogenic microorganisms
The use of natural preservatives became of great interest; good examples of these natural preservation agents are plant peels. The …
Article scientifique
Secondary metabolites and biodiversity of actinomycetes
BACKGROUND: The ability to produce microbial bioactive compounds makes actinobacteria one of the most explored microbes among prokaryotes. The secondary …
Article scientifique
Alterations of PTEN and SMAD4 methylation in diagnosis of breast cancer: implications of methyl II PCR assay
BACKGROUND: Diagnosis of breast cancer is more complicated due to lack of minimal invasive biomarker with sufficient precision. DNA methylation …
Article scientifique
Actinomycete strain type determines the monodispersity and antibacterial properties of biogenically synthesized silver nanoparticles
BACKGROUND: Bio-nanotechnology is considered as one of the low-cost approaches that have been utilized in production of nanomaterials. The current …
Article scientifique
DNA barcoding of the spider crab Menaethius monoceros (Latreille, 1825) from the Red Sea, Egypt
BACKGROUND: Most spider crab species inhabiting the Red Sea have not been characterized genetically, in addition to the variation and …
Article scientifique
Status of insecticide susceptibility in Anopheles arabiensis and detection of the knockdown resistance mutation (kdr) concerning agricultural practices from Northern Sudan state, Sudan
BACKGROUND: Chemical control has been the most efficient method in mosquito control, the development of insecticide resistance in target populations …
Article scientifique
HCl-induced acute lung injury: a study of the curative role of mesenchymal stem/stromal cells and cobalt protoporphyrin
BACKGROUND: This study was designed to investigate bone marrow mesenchymal stem/stromal cells (BM-MSCs) and cobalt protoporphyrin (CoPP) curable effects on …
Article scientifique
Epigenetic effects toward new insights as potential therapeutic target in B-thalassemia
BACKGROUND: Fetal hemoglobin (HbF) induction has shown promise for the treatment of β-hemoglobinopathies. HbF induction in β-thalassemia could overcome ineffective …
Article scientifique
Correlation of methylation status in MTHFR promoter region with recurrent pregnancy loss
BACKGROUND: DNA methylation is an epigenetic process for modifying transcription factors in various genes. Methylenetetrahydrofolate reductase (MTHFR) stimulates synthesis of …
Article scientifique
Predicting the bioactivity of 2-alkoxycarbonylallyl esters as potential antiproliferative agents against pancreatic cancer (MiaPaCa-2) cell lines: GFA-based QSAR and ELM-based models with molecular docking
The number of cancer-related deaths is on the increase, combating this deadly disease has proved difficult owing to resistance and …
Article scientifique
Optimization of extracellular ethanol-tolerant β-glucosidase production from a newly isolated Aspergillus sp. DHE7 via solid state fermentation using jojoba meal as substrate: purification and biochemical characterization for biofuel preparation
The increasing demand and the continuous depletion in fossil fuels have persuaded researchers to investigate new sources of renewable energy. …
Article scientifique
Characterization and optimization of extracellular enzymes production by Aspergillus niger strains isolated from date by-products
BACKGROUND: This work aims to study the optimal conditions of the fermentation culture medium used for the production of extracellular …
Article scientifique
Association of some dietary ingredients, vitamin D, estrogen, and obesity polymorphic receptor genes with bone mineral density in a sample of obese Egyptian women
BACKGROUND: Although many environmental factors play an important role in bone mass density (BMD) variation, genetic influences account for 60-85% …
Article scientifique
Statistical factorial designs for optimum production of thermostable α-amylase by the degradative bacterium Parageobacillus thermoglucosidasius Pharon1 isolated from Sinai, Egypt
BACKGROUND: This study aimed to isolate potent thermophilic and amylolytic bacteria from a hot spring of Pharaoh's bath, Sinai, Egypt, …
Article scientifique
Patterns of genetic structure and evidence of Egyptian Citrus rootstock based on informative SSR, LTR-IRAP and LTR-REMAP molecular markers
BACKGROUND: Releasing the draft genome of sweet orange provides useful information on genetic structure and molecular marker association with heritable …