27 publication(s) trouvée(s)
Article scientifique
Ethical design as a prerequisite for translational microbiome science
Human microbiome research is expanding globally, yet remains dominated by samples, institutions, and leadership from the Global North. This imbalance …
Article scientifique
Host clustering of Campylobacter species and enteric pathogens in a longitudinal cohort of infants, family members and livestock in rural Eastern Ethiopia
BACKGROUND: Livestock are recognized as major reservoirs for Campylobacter species and other enteric pathogens, posing infection risks to humans. High …
Article scientifique
Interplay between the gut microbiome and typhoid fever: insights from endemic countries and a controlled human infection model
BACKGROUND: Typhoid fever is a systemic infection caused by Salmonella enterica serovar Typhi (S. Typhi) invasion from the gut lumen. …
Article scientifique
Quantitative profiling of the vaginal microbiota improves resolution of the microbiota-immune axis
BACKGROUND: The composition of the vaginal microbiota is closely linked to adverse sexual and reproductive health outcomes, due in part …
Article scientifique
Substantial viral diversity in bats and rodents from East Africa: insights into evolution, recombination, and cocirculation
BACKGROUND: Zoonotic viruses cause substantial public health and socioeconomic problems worldwide. Understanding how viruses evolve and spread within and among …
Article scientifique
Differential effects of antiretroviral treatment on immunity and gut microbiome composition in people living with HIV in rural versus urban Zimbabwe
BACKGROUND: The widespread availability of antiretroviral therapy (ART) has dramatically reduced mortality and improved life expectancy for people living with …
Article scientifique
Succession and determinants of the early life nasopharyngeal microbiota in a South African birth cohort
BACKGROUND: Bacteria colonizing the nasopharynx play a key role as gatekeepers of respiratory health. Yet, dynamics of early life nasopharyngeal …
Article scientifique
Sputum bacterial load and bacterial composition correlate with lung function and are altered by long-term azithromycin treatment in children with HIV-associated chronic lung disease
BACKGROUND: Long-term azithromycin (AZM) treatment reduces the frequency of acute respiratory exacerbation in children and adolescents with HIV-associated chronic lung …
Article scientifique
Assessing the causes and consequences of gut mycobiome variation in a wild population of the Seychelles warbler
BACKGROUND: Considerable research has focussed on the importance of bacterial communities within the vertebrate gut microbiome (GM). However, studies investigating …
Article scientifique
Biogeographical survey of soil microbiomes across sub-Saharan Africa: structure, drivers, and predicted climate-driven changes
BACKGROUND: Top-soil microbiomes make a vital contribution to the Earth's ecology and harbor an extraordinarily high biodiversity. They are also …
Article scientifique
Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression
BACKGROUND: Women with a cervicovaginal microbiota dominated by Lactobacillus spp. are at reduced risk of acquiring sexually transmitted infections including …
Article scientifique
Correction to: Microbial function and genital inflammation in young South African women at high risk of HIV infection
Article scientifique
Immunogenetic variation shapes the gut microbiome in a natural vertebrate population
BACKGROUND: The gut microbiome (GM) can influence many biological processes in the host, impacting its health and survival, but the …
Article scientifique
Correction to: Human microbiota research in Africa: a systematic review reveals gaps and priorities for future research
An amendment to this paper has been published and can be accessed via the original article.
Article scientifique
Human microbiota research in Africa: a systematic review reveals gaps and priorities for future research
BACKGROUND: The role of the human microbiome in health and disease is an emerging and important area of research; however, …
Article scientifique
Shifts in microbial diversity, composition, and functionality in the gut and genital microbiome during a natural SIV infection in vervet monkeys
BACKGROUND: The microbiota plays an important role in HIV pathogenesis in humans. Microbiota can impact health through several pathways such …
Article scientifique
Microbial function and genital inflammation in young South African women at high risk of HIV infection
BACKGROUND: Female genital tract (FGT) inflammation is an important risk factor for HIV acquisition. The FGT microbiome is closely associated …
Article scientifique
Immunoglobulin recognition of fecal bacteria in stunted and non-stunted children: findings from the Afribiota study
BACKGROUND: Child undernutrition is a global health issue that is associated with poor sanitation and an altered intestinal microbiota. Immunoglobulin …
Article scientifique
Multi-proxy analyses of a mid-15th century Middle Iron Age Bantu-speaker palaeo-faecal specimen elucidates the configuration of the ‘ancestral’ sub-Saharan African intestinal microbiome
BACKGROUND: The archaeological incidence of ancient human faecal material provides a rare opportunity to explore the taxonomic composition and metabolic …
Article scientifique
Microbial communities of the house fly Musca domestica vary with geographical location and habitat
House flies (Musca domestica) are widespread, synanthropic filth flies commonly found on decaying matter, garbage, and feces as well as …
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