14 publication(s) trouvée(s)
Article scientifique
Pathogenic cytokines in thrombotic microangiopathies: molecular insights and therapeutic targets
Thrombotic microangiopathies (TMAs) are a heterogeneous group of disorders characterized by endothelial damage, microvascular thrombosis, thrombocytopenia, and microangiopathic hemolytic anemia. …
Article scientifique
Modulating autism spectrum disorder pathophysiology using a trace amine-focused approach: targeting the gut
Autism spectrum disorder (ASD) affects approximately 1% of the population directly, but also a much higher proportion (family and caregivers) …
Article scientifique
Impact of intermittent fasting versus vitamin D on high fat fructose-induced pancreatic steatosis: possible role of aquaporins
BACKGROUND: The molecular basis of pancreatic steatosis is not entirely known. Aquaporins (AQPs) are integral membrane proteins involved in a …
Article scientifique
Regulatory role of the lncRNAs MIAT and PVT1 in Behçet’s disease through targeting miR-93-5p and miR-124-3p
BACKGROUND: Noncoding RNAs play pivotal roles in the process of autoimmune diseases. However, the definite contributions of these molecules to …
Article scientifique
The pre-conception maternal exposure to Sofosbuvir affects the mitochondrial biogenesis in prenatal fetal tissues: Experimental study on rats
BACKGROUND: Hepatitis C virus (HCV) infection is a global public health problem and Egypt has the highest HCV prevalence worldwide. …
Article scientifique
Excitatory and inhibitory neuronal signaling in inflammatory and diabetic neuropathic pain
Abstract Pain, although unpleasant, is an essential warning mechanism against injury and damage of the organism. An intricate network of …
Article scientifique
Clinical application of RUBCN/SESN2 mediated inhibition of autophagy as biomarkers of diabetic kidney disease
BACKGROUND: Deregulated autophagy in diabetes has been a field of many experimental studies recently. Impaired autophagy in diabetic kidneys orchestrates …
Article scientifique
Chronotherapeutic neuroprotective effect of verapamil against lipopolysaccharide-induced neuroinflammation in mice through modulation of calcium-dependent genes
Abstract Background Neuroinflammation is a major mechanism in neurodegenerative diseases such as Alzheimer’s disease (AD), which is a major healthcare …
Article scientifique
Quercetin mitigates rheumatoid arthritis by inhibiting adenosine deaminase in rats
Abstract Rheumatoid arthritis (RA) is a chronic inflammatory joint disease characterized by synovial proliferation and bone destruction. Adenosine deaminase (ADA) …
Article scientifique
LRRC4 functions as a neuron-protective role in experimental autoimmune encephalomyelitis
Abstract Background Leucine rich repeat containing 4 (LRRC4), also known as netrin-G ligand-2 (NGL-2), belongs to the superfamily of LRR …
Article scientifique
Correction to: miRNA-23b as a biomarker of culture-positive neonatal sepsis
An amendment to this paper has been published and can be accessed via the original article.
Article scientifique
miRNA-23b as a biomarker of culture-positive neonatal sepsis
BACKGROUND: Neonatal sepsis remains an important cause of morbidity and mortality. The ability to quickly and accurately diagnose neonatal sepsis …
Article scientifique
Serum a proliferation-inducing ligand and MicroRNA-223 are associated with rheumatoid arthritis: diagnostic and prognostic implications
BACKGROUND: Current blood-based tests for rheumatoid arthritis (RA) have inherent limitations, necessitating the need for additional new biomarkers for its …
Article scientifique
Serologic features of cohorts with variable genetic risk for systemic lupus erythematosus
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease with genetic, hormonal, and environmental influences. In Western Europe and North …