397 publication(s) trouvée(s)
Article scientifique
Pasteurella sp. associated with fatal septicaemia in six African elephants
The sudden mortality of African elephants (Loxodonta africana) in Botswana and Zimbabwe in 2020 provoked considerable public interest and speculation. …
Article scientifique
Epidemiology of Plasmodium malariae and Plasmodium ovale spp. in Kinshasa Province, Democratic Republic of Congo
Reports suggest non-falciparum species are an underappreciated cause of malaria in sub-Saharan Africa but their epidemiology is ill-defined, particularly in …
Article scientifique
A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa
Invasive non-typhoidal Salmonella (iNTS) disease manifesting as bloodstream infection with high mortality is responsible for a huge public health burden …
Article scientifique
SARS-CoV-2 genomic surveillance in wastewater as a model for monitoring evolution of endemic viruses
As global SARS-CoV-2 burden and testing frequency have decreased, wastewater surveillance has emerged as a key tool to support clinical …
Article scientifique
Sugar-sweetened beverage intakes among adults between 1990 and 2018 in 185 countries
Sugar-sweetened beverages (SSBs) are associated with cardiometabolic diseases and social inequities. For most nations, recent estimates and trends of intake …
Article scientifique
Estimating the burden of severe malarial anaemia and access to hospital care in East Africa
Severe malarial anaemia can be fatal if not promptly treated. Hospital studies may under-represent the true burden because cases often …
Article scientifique
Metagenomic sequencing of post-mortem tissue samples for the identification of pathogens associated with neonatal deaths
Postmortem minimally invasive tissue sampling together with the detailed review of clinical records has been shown to be highly successful …
Article scientifique
Multi-trait discovery and fine-mapping of lipid loci in 125,000 individuals of African ancestry
Most genome-wide association studies (GWAS) for lipid traits focus on the separate analysis of lipid traits. Moreover, there are limited …
Article scientifique
The promise of data science for health research in Africa
Data science health research promises tremendous benefits for African populations, but its implementation is fraught with substantial ethical governance risks …
Article scientifique
Elevated binding and functional antibody responses to SARS-CoV-2 in infants versus mothers
Infant antibody responses to viral infection can differ from those in adults. However, data on the specificity and function of …
Article scientifique
Metagenomic surveillance uncovers diverse and novel viral taxa in febrile patients from Nigeria
Effective infectious disease surveillance in high-risk regions is critical for clinical care and pandemic preemption; however, few clinical diagnostics are …
Article scientifique
The cost of electrifying all households in 40 Sub-Saharan African countries by 2030
Electrifying sub-Saharan Africa (SSA) requires major investments and policy intervention. Existing analyses focus on the levelized cost of electricity at …
Article scientifique
Adoption of climate-resilient groundnut varieties increases agricultural production, consumption, and smallholder commercialization in West Africa
As part of the climate-smart agriculture approach, the adoption of climate-resilient crop varieties has the potential to build farmers' climate …
Article scientifique
Genome-wide association studies reveal novel loci associated with pyrethroid and organophosphate resistance in Anopheles gambiae and Anopheles coluzzii
Resistance to insecticides in Anopheles mosquitoes threatens the effectiveness of malaria control, but the genetics of resistance are only partially …
Article scientifique
Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: the METS-microbiome study
The relationship between microbiota, short chain fatty acids (SCFAs), and obesity remains enigmatic. We employ amplicon sequencing and targeted metabolomics …
Article scientifique
A small area model to assess temporal trends and sub-national disparities in healthcare quality
Monitoring subnational healthcare quality is important for identifying and addressing geographic inequities. Yet, health facility surveys are rarely powered to …
Article scientifique
Circulating trans fatty acids are associated with prostate cancer in Ghanaian and American men
The association between fatty acids and prostate cancer remains poorly explored in African-descent populations. Here, we analyze 24 circulating fatty …
Article scientifique
Detecting temporal and spatial malaria patterns from first antenatal care visits
Pregnant women attending first antenatal care (ANC) visits represent a promising malaria surveillance target in Sub-Saharan Africa. We assessed the …
Erratum
Author Correction: Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects
Author notes Melanie Bahlo Present address: Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, …
Article scientifique
Using mortuary and burial data to place COVID-19 in Lusaka, Zambia within a global context
Reported COVID-19 cases and associated mortality remain low in many sub-Saharan countries relative to global averages, but true impact is …